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Traditional Chinese medicine composition for treating cerebrovascular disease and application thereof

A technology of cerebrovascular disease and composition, applied in the field of traditional Chinese medicine and natural medicine, can solve the problems of poor effect and side effects, and achieve the effect of good effect, no side effects, and less dosage

Active Publication Date: 2011-05-11
HEHUANG PHARMA SHANGHAI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0015] The object of the present invention is to provide a kind of traditional Chinese medicine composition for treating cerebrovascular disease and its preparation method and application, described this medicine composition for the treatment of cerebrovascular disease and its preparation method will solve the problems in the prior art The technical problems that the drugs for treating cerebrovascular diseases are not effective and have side effects

Method used

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  • Traditional Chinese medicine composition for treating cerebrovascular disease and application thereof
  • Traditional Chinese medicine composition for treating cerebrovascular disease and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] Extraction of Angelica Oil and Ferulic Acid

[0042] Preparation of the active ingredients of the main drug

[0043] 1. Take angelica, cinnamon and ginseng according to the formula in table 1

[0044] 2. Extraction of Angelica Oil and Ferulic Acid

[0045] Angelica supercritical extraction: take 20-mesh Angelica herb, extract at 28MPa, extract at 40°C, CO 2 Flow 20L·h -1 , extraction time 1.5h, supercritical extraction to obtain angelica oil.

[0046] Extraction process of angelica ferulic acid: angelica medicinal material (crushed into 20-50 mesh, residue after volatile oil extraction treatment), weigh the appropriate amount of the above raw materials, add ethanol equivalent to 8 times the weight of the medicinal material, the ethanol concentration is 70%, shake well , refluxed in a water bath for 40 minutes, and the temperature of the water bath was 60-80° C., extracted three times, and filtered separately to obtain an extract. Combine the extracts, recover the s...

Embodiment 2

[0054] Embodiment 2 tablet preparation

[0055] Element

[0056] Main medicinal ingredients raw materials (drying and obtaining of formula 1 of embodiment 1)

[0057] According to the usual tablet preparation method, after the pharmaceutical composition is uniformly mixed with other auxiliary materials, it is wet-granulated, dried, granulated, and magnesium stearate is added to mix uniformly, compressed, coated, and made into 1000 tablets.

Embodiment 3

[0058] Embodiment 3 capsule preparation

[0059] According to formula 1 of embodiment 1, prepare 250g product, according to the operation of common capsule, medicine is filled into suitable capsule, sealing makes 1000 capsules.

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Abstract

The invention provides a traditional Chinese medicine composition for treating cerebrovascular disease and preparation and application thereof, belonging to the field of medicine. The traditional Chinese medicine composition provided by the invention comprises 23-43% of angelica sinensis, 23-43% of cinnamon and balance of ginseng in percentage by weight. The invention also provides the preparation and pharmaceutical application of the traditional Chinese medicine composition. The traditional Chinese medicine composition provided by the invention can be used for treating cerebrovascular disease, in particular ishemic stroke, has small dose, good effect and no side effect, and is a safe and effective traditional Chinese medicine preparation.

Description

Technical field: [0001] The invention belongs to the technical field of traditional Chinese medicine and natural medicine, and in particular relates to a traditional Chinese medicine composition for treating cerebrovascular diseases and an application thereof. Background technique: [0002] In recent years, the incidence of cerebrovascular disease has been increasing year by year, and it has become one of the three diseases with the highest fatality rate along with myocardial infarction and malignant tumors. [0003] Cerebrovascular disease, also known as stroke, is a neurological disease that causes brain or carotid artery disease that dominates the brain, causing local blood circulation disorders and acute brain damage. It is known as "stroke" because of its rapid onset like the wind blowing; it is also called "stroke" because of its dangerous condition and high mortality rate. [0004] Cerebrovascular diseases can be divided into two categories: hemorrhagic or ischemic. ...

Claims

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Application Information

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IPC IPC(8): A61K36/54A61P9/00A61P9/10C07C59/64C11B1/10
Inventor 郭安詹常森周文娟陈忠樑
Owner HEHUANG PHARMA SHANGHAI
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