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32results about How to "Excellent pharmacodynamic activity" patented technology

Medicinal composition for treating rhinitis and application thereof

The invention provides a medicinal composition for treating rhinitis. The medicinal composition is prepared from the following raw materials in parts by weight: 5-15 parts of magnolia flower essential oil, 2-8 parts of centipeda minima essential oil, 1-5 parts of mint essential oil, 2-8 parts of agastache rugosa essential oil, 2-8 parts of wild chrysanthemum essential oil, and 1-5 parts of cassia twig essential oil. The invention further provides a preparation method and application of the composition. The study results show that the medicinal composition has a good therapeutic effect on chronic rhinitis and allergic rhinitis, is precise and appropriate in compatibility, and obviously superior to the medicinal composition with a different formula in pharmacological activity; meanwhile, the medicinal composition is not required to be orally taken or injected, so that the patient compliance is better and a novel choice is provided for clinical medication.
Owner:CHENGDU COMFAITH PHARMA

Low-temperature preparation method for American cockroach extract

The invention provides a low-temperature preparation method for an American cockroach extract. The method comprises the following steps: (1) taking American cockroaches or degreased American cockroaches, adding a solvent, extracting at low temperatures and combining an extraction liquid; and (2) recovering the solvent from the extraction liquid at a reduced pressure and concentrating to obtain the American cockroach extract. According to the novel process for extracting the American cockroach extract provided by the invention, the active ingredients of the American cockroaches are effectively retained, and the pharmacodynamics activity of the obtained extract is superior to the product which is prepared in the prior art, so that the method has a relatively good market application prospect.
Owner:SICHUAN GOODDOCTOR PANXI PHARMA

Food, health product or pharmaceutical composition with effect of protecting liver

ActiveCN104257811AGood liver protection and enzyme lowering effectCompatibilityDigestive systemNatural extract food ingredientsMedicineSemen
The invention provides a food, a health product or a pharmaceutical composition with an effect of protecting liver. The raw materials comprise the following components in parts by weight: 0.5-1.5 parts of cape jasmine fruit, 1-2 parts of dandelion, 0.5-1 part of hawthorn, 1 part of lotus leaf and 0.5-1 part of semen cassiae. The research proves that the composition can obviously improve various indexes of chemical liver injury, has good effects of protecting liver and lowering transaminase and is precise and appropriate in compatibility, a synergistic effect is achieved, and the pharmacodynamics activity is obviously superior to that of each single raw material.
Owner:SICHUAN ZHONGDING TRADITIONAL CHINESE MEDICINE DEV

Phellinus igniarius and ganoderma lucidum powder and preparation method thereof

The invention discloses phellinus igniarius and ganoderma lucidum powder. The phellinus igniarius and ganoderma lucidum powder is prepared from the following components in parts by weight: 8-12 parts of ganoderma lucidum powder of which the sporoderm-broken rate reaches 98%, 4-6 parts of a phellinus igniarius extract, 4-6 parts of a cordyceps flower extract and 4-6 parts of a hericium erinaceus extract. The effective active ingredients, such as active ingredients of polysaccharide and terpene in phellinus igniarius, cordyceps flowers and the hericium erinaceus are extracted through a unique extraction technology to the maximum extent; the medicinal effects or healthcare effects of the phellinus igniarius, the cordyceps flowers and the hericium erinaceus are developed to the maximum extent; the bioavailability is improved; and the dosage of native medicinal materials of the phellinus igniarius, the cordyceps flowers and the hericium erinaceus is correspondingly reduced. The composition has an excellent effect of enhancing the immunity and is precise and appropriate in compatibility, the synergistic effect is developed and the pharmacological activity is obviously superior to that of single medicines.
Owner:四川岚晟生物科技股份有限公司

Tongmai oral liquid raw material extract

The invention provides a Tongmai oral liquid raw material extract, which is characterized in that the ratio of Tongmai oral liquid raw materials is as follows: salvia miltiorrhiza: radix puerariae: ligusticum wallichii=1: 1: 1, and in the raw material extract, the weight ratio of the active ingredients is as follows: tanshinol: puerarin: ferulic acid: tanshinone IIA=(0.9-1.3): (1.0-1.3): (1.0-1.2): 1.0. According to the invention, alcohol and water are taken as solvents to extract the Tongmai oral liquid raw materials together; although the extraction efficiency for the active ingredients is not as good as extraction by using 60% alcohol, the raw material extract prepared by the method is obviously superior to the previous preparation process and the 60% alcohol extract with the highest active ingredient content in pharmacological activity; an unexpected technical effect is achieved; and the Tongmai oral liquid raw material extract is advantageous for the patients suffering cardiovascular and cerebrovascular diseases.
Owner:SICHUAN GOODDOCTOR PHARMA GRP

Solid drink with stomach nourishing and spleen tonifying effects and preparation method of solid drink

InactiveCN107616398AIncrease market useEnhance the original effectDigestive systemPlant ingredientsMaltodextrinStomach
The invention discloses a solid drink with stomach nourishing and spleen tonifying effects and a preparation method of the solid drink. The solid drink is prepared from 20-40 parts of morchella, 20-40parts of hericium erinaceus, 10-30 parts of flos lablab album, 10-20 parts of semen raphani and 5 parts of maltodextrin. The preparation method of the solid drink comprises the steps as follows: themorchella, the hericium erinaceus, the flos lablab album and the semen raphani are subjected to extraction and concentration respectively, extracts are mixed and uniformly mixed with the maltodextrin,wet granulation, low-temperature drying and packaging are conducted, and the solid drink with stomach nourishing and spleen tonifying effects is obtained. The prepared solid drink has the excellent stomach nourishing and spleen tonifying effects, has high effective ingredient content and is easy to absorb and utilize after being orally taken, components of the solid drink are properly matched andplay a synergistic effect, and the pharmaceutical activity is obviously superior to that of each raw material.
Owner:四川岚晟生物科技股份有限公司

Traditional Chinese medicine composition for treating cerebrovascular disease and application thereof

The invention provides a traditional Chinese medicine composition for treating cerebrovascular disease and preparation and application thereof, belonging to the field of medicine. The traditional Chinese medicine composition provided by the invention comprises 23-43% of angelica sinensis, 23-43% of cinnamon and balance of ginseng in percentage by weight. The invention also provides the preparation and pharmaceutical application of the traditional Chinese medicine composition. The traditional Chinese medicine composition provided by the invention can be used for treating cerebrovascular disease, in particular ishemic stroke, has small dose, good effect and no side effect, and is a safe and effective traditional Chinese medicine preparation.
Owner:HEHUANG PHARMA SHANGHAI

Pharmaceutical composition for treating diabetes, and preparation method and application thereof

A provided pharmaceutical composition for treating diabetes is a preparation prepared from the following bulk drugs in parts by weight: 10-60 parts of coptis, 10-60 parts of radix asparagi, 10-60 parts of rehmannia glutinosa, 10-60 parts of dark plum, 5-20 parts of ginseng and 2-12 parts of cinnamomum cassia. The invention also provides a preparation method and application of the pharmaceutical composition. Tests show that: the pharmaceutical composition is precise and appropriate in compatability, is capable of effectively reducing blood sugar, is substantially more excellent in drug effect activity than classic prescription Lianmeitang and Jiaotai pill, and helps to provide a new choice for clinical medication for treating diabetes.
Owner:TEACHING HOSPITAL OF CHENGDU UNIV OF T C M

Solid beverage having effects of quieting heart and soothing nerves and making method of solid beverage

The invention discloses a solid beverage having effects of quieting the heart and soothing nerves and a making method of the solid beverage. The solid beverage is prepared from the following raw materials in parts by weight: 20-40 parts of armillaria mellea, 20-30 parts of poria cocos, 20-30 parts of parched wild jujube seeds, 15-20 parts of rhizoma polygonati odorati, and 1-3 parts of maltodextrin. The making method of the solid beverage comprises the following steps of performing extraction and concentration on the armillaria mellea, the poria cocos, the parched wild jujube seeds and the rhizoma polygonati odorati, merging extracts, uniformly mixing the merged extracts with the maltodextrin, performing wet granulation, performing low temperature drying and performing packing so as to obtain the solid beverage having effects of quieting the heart and soothing nerves. The prepared solid beverage has excellent efficacy of quieting the heart and soothing the nerves, and is high in content of effective components and easy to absorb and utilize after being taken orally. The composition is precise and appropriate in compatibility, the synergistic effect is elaborated and the drug effectactivity of the solid beverage is higher than that of single-taste raw materials.
Owner:四川岚晟生物科技股份有限公司

Amidoxime compound and application thereof to preparation of medicines for inhibiting cancer cell proliferation

The invention discloses an amidoxime compound and application thereof to preparation of medicines for inhibiting cancer cell proliferation, and relates to the field of medicinal chemistry. The amidoxime compound provided by the invention has capacity of inhibiting the cancer cell proliferation, so that an aim of treating cancers is achieved. The amidoxime compound particularly has excellent activity of inhibiting the cancer cell proliferation of human cutaneous melanoma cells (A375), human lung cancer cells (A549), human gastric carcinoma cells (MGC80-3), and human hepatoma cells (HepG2). The structure of the amidoxime compound is as shown in the specification. In the formula, n is 1-6, and R refers to alkyl or substituted alkyl.
Owner:BEIJING UNIV OF CHEM TECH

Traditional Chinese medicine composition for treating diabetes

The invention provides a traditional Chinese medicine composition for curing diabetes. The composition is obviously superior to the extract of each single medical herb, is safe and has no obvious toxic and side effects. The composition is prepared by the following raw materials according to the parts by weight: 51-746 parts of astragalus root extract and 285-2700 parts of loquat leaf extract, wherein, the astragalus root extract is prepared via astragalus root through water extraction or alcohol extraction, the content of the polysaccharide (active component) is higher than 80 percent (weight percentage), the loquat leaf extract is prepared via loquat leaves through water extraction or alcohol extraction, and the active component thereof, i.e. the total triterpenic acid from the loquat leaves comprises the following components 20-40 parts of maloic acid, 2-6 parts of oleanolic acid, 20-40 parts of corosolic acid and 8-20 parts of cralaegolic acid, wherein, the content of the total triterpenic acid from the loquat leaves is higher than 85 percent (weight percentage).
Owner:CHENGDU UNIV

Application of berberine dimer analog derivatives in the preparation of drugs for preventing and treating Parkinson's disease

The invention discloses the application of berberine dimer analog derivatives in the preparation of medicines for preventing and treating Parkinson's disease. The structural formula of the berberine dimer analog derivative is shown in formula I. In the present invention, it is found that berberine dimer analogue derivatives or pharmaceutically acceptable salts thereof show better pharmacodynamic activity than the parent compound berberine on the in vitro cell model of Parkinson's disease, and it can obviously Improve the behavior of Parkinson's disease model mice, increase the number of dopaminergic neurons in the substantia nigra compacta, and increase the levels of dopamine and 3,4-dihydroxyphenylacetic acid in the striatum. Therefore, berberine dimer analog derivatives or pharmaceutically acceptable salts thereof can be made into related medicines for preventing and treating Parkinson's disease.
Owner:JINAN UNIVERSITY

Preparation of dithiocarbamate compound and application of dithiocarbamate compound in drug for inhibiting cancer cell proliferation and/or treating cancer

The invention discloses preparation of dithiocarbamate compounds and application of the dithiocarbamate compound in a drug for inhibiting cancer cell proliferation and / or treating cancer, relating tothe field of pharmaceutical chemistry. The dithiocarbamate compounds have structures as shown in a general formula (I) or (II) in the description, wherein R is alkyl, acylamino alkyl, acyl alkyl, keto-alkyl, an ester group-alkyl, carboxyl alkyl, dicarboxyl alkyl, aryl, alkyl-substituted aryl and the like. The dithiocarbamate compounds (sulforaphene derivative and sulforaphane derivative) providedby the invention have the capacity of inhibiting cancer cell proliferation, and particularly has excellent cancer cell proliferation inhibiting activity in the aspects of inhibiting malignant melanomacell strains 375 of human skin, human hepatocellular carcinoma cells SMMC-7721, human lung cancer A549, human colon cancer cells HCT116 and human cervical carcinoma cells Hela.
Owner:BEIJING UNIV OF CHEM TECH

Quinazoline derivatives and their preparation methods and applications in medicine

The present invention relates to a quinazoline derivative and its preparation method and application in medicine, specifically the present invention relates to a quinazoline derivative or its stereoisomer, hydrate, metabolite, solvate, pharmaceutical The acceptable salts, co-crystals or prodrugs relate to their preparation methods, their pharmaceutical compositions and their use in medicine, especially as EGFR / HER2 dual-target inhibitors.
Owner:HAISCO PHARMA GRP INC

Smilax scobomocaulis polysaccharide extractive and preparation method therof

The invention provides a Smilax scobomocaulis polysaccharide extractive with polysaccharide content greater than 20% w / w. The invention also provides a preparation method and application of the extractive. The invention also provides a composition based on the extractive and for the treatment of pelvic inflammation The research of the invention discovers that the Smilax scobomocaulis polysaccharide has good effects of resisting inflammation, promoting blood circulation to remove blood stasis and enhancing immune function, and has a good therapeutic effect on pelvic inflammatory diseases.
Owner:SICHUAN GOODDOCTOR PHARMA GRP

Traditional Chinese medicine compound type antibiotic-free immunity-enhancing feed additive and preparation method thereof

The invention provides a traditional Chinese medicine compound type antibiotic-free immunity-enhancing feed additive and a preparation method thereof. The traditional Chinese medicine compound type antibiotic-free immunity-enhancing feed additive is prepared from the following raw material components: 10 to 20 parts of fructus ligustri lucidi crude extract, 10 to 20 parts of folium artemisiae argyi crude extract, 5 to 10 parts of rhizoma belamcandae crude extract, 5 to 10 parts of algal polysaccharide soluble powder, 5 to 10 parts of tourmaline powder and 50 to 80 parts of auxiliary materials; the preparation method comprises the following steps: weighing the raw materials and mixing to prepare powder; preparing a granular preparation by adopting dry-process granulation and arranging a dry-process granulator. The traditional Chinese medicine compound type antibiotic-free immunity-enhancing feed additive provided by the invention has the beneficial effects that a plurality of components with an immunity-enhancing effect are compounded according to a certain ratio, wherein the fructus ligustri lucidi crude extract, the folium artemisiae argyi crude extract, the rhizoma belamcandae crude extract and the algal polysaccharide soluble powder are extracted and prepared according to a special technology; after the powder in the formula is uniformly mixed, the powder is prepared into granules by adopting a dry-process granulation technology; an experiment result shows that various immunity indexes of pig bodies are improved through the compound formula and the pharmacological activity is obviously better than that of each single raw material; the effect of the dry-process granulation is stronger than that of a common granulation method.
Owner:HENAN HUITONG TIANXIA BIO ENG

Paulownia flower-containing animal immunity enhancing medicinal composition

The invention discloses a paulownia flower-containing animal immunity enhancing medicinal composition. The composition is a preparation prepared from Radix Astragali and paulownia flowers. The invention also discloses a preparation method of the medicinal composition, and a use of the medicinal composition. The medicinal composition combining Radix Astragali with the paulownia flowers has a good immunity enhancing effect, has better medicine effect activity than single Radix Astragali and paulownia flowers, and also has the advantages of small medicine variety number, low cost and excellent clinic application prospect. The medicinal composition can be combined with antibiotics to effectively treat porcine reproductive and respiratory syndrome, so a new choice is provided for clinic medicine use.
Owner:CHENGDU QIANKUN VETERINARY PHARMA

Loquat-leaf-containing veterinary drug combination for treating livestock and poultry respiratory disease syndrome

The invention provides an veterinary drug combination for treating livestock and poultry respiratory disease syndrome. The veterinary drug combination is a preparation prepared by the following medical raw materials by weight: 8-27 parts of echinacea, 24-35 parts of loquat leaf, 9-28 parts of herba andrographitis and 3-9 parts of cubeba. The invention further provides a preparation method and a purpose of the veterinary drug combination. The livestock and poultry respiratory disease syndrome, such as porcine pneumonia and gallinaceous viral influenza can be effectively treated by the drug combination. The curative rate is high, and the pharmacological activity is obviously superior to that of a commercial available drug. A new choice is provided for clinic drugs.
Owner:CHENGDU QIANKUN VETERINARY PHARMA +1
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