Supercharge Your Innovation With Domain-Expert AI Agents!

Tongmai oral liquid raw material extract

A technology for raw materials and oral liquids, applied in the field of Tongmai oral liquid raw material drug extracts, can solve problems such as neglect

Active Publication Date: 2013-08-14
SICHUAN GOODDOCTOR PHARMA GRP
View PDF1 Cites 4 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Therefore, the inventor draws a preliminary conclusion from the prior art: the current preparation process of Tongmai Oral Liquid has certain defects. It only emphasizes the water-soluble components of the three medicinal materials, while ignoring tanshinone ⅡA, ligustilide, etc. Fat-soluble active ingredients

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Tongmai oral liquid raw material extract
  • Tongmai oral liquid raw material extract
  • Tongmai oral liquid raw material extract

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0043] The preparation of embodiment 1 crude drug extract of the present invention

[0044] Take 10g of Salvia miltiorrhiza, Pueraria lobata and Chuanxiong each (1:1:1), mix well, add 300mL of 95% v / v ethanol, heat to reflux for 1h, filter the extract, recover ethanol from the filtrate and concentrate to an appropriate amount. Add 300 mL of 50% v / v ethanol to the dregs, heat and reflux for 1 hour, filter the extract, recover ethanol from the filtrate and concentrate to an appropriate amount. Add 300 mL of water to the dregs, decoct for 2 hours, filter the decoction, evaporate to dryness, and combine the three extracts to obtain the crude drug extract of the present invention.

Embodiment 2

[0045] The preparation of embodiment 2 crude drug extracts of the present invention

[0046] Take 10g of Salvia miltiorrhiza, Pueraria lobata and Chuanxiong each (1:1:1), mix well, add 400mL of 70% v / v ethanol, heat to reflux for 1h, filter the extract, recover ethanol from the filtrate and concentrate to an appropriate amount. Add 300 mL of 40% v / v ethanol to the dregs, heat and reflux for 1 hour, filter the extract, recover ethanol from the filtrate and concentrate to an appropriate amount. Add 300 mL of water to the dregs, decoct for 2 hours, filter the decoction, evaporate to dryness, and combine the three extracts to obtain the crude drug extract of the present invention.

Embodiment 3

[0047] The preparation of embodiment 3 crude drug extracts of the present invention

[0048] Take 10g of Salvia miltiorrhiza, Pueraria lobata and Chuanxiong each (1:1:1), mix well, add 200mL of 85% v / v ethanol, heat to reflux for 1h, filter the extract, recover ethanol from the filtrate and concentrate to an appropriate amount. Add 200 mL of 60% v / v ethanol to the dregs, heat and reflux for 1 hour, filter the extract, recover ethanol from the filtrate and concentrate to an appropriate amount. Add 200 mL of water to the dregs, decoct for 2 hours, filter the decoction, evaporate to dryness, and combine the three extracts to obtain the crude drug extract of the present invention.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention provides a Tongmai oral liquid raw material extract, which is characterized in that the ratio of Tongmai oral liquid raw materials is as follows: salvia miltiorrhiza: radix puerariae: ligusticum wallichii=1: 1: 1, and in the raw material extract, the weight ratio of the active ingredients is as follows: tanshinol: puerarin: ferulic acid: tanshinone IIA=(0.9-1.3): (1.0-1.3): (1.0-1.2): 1.0. According to the invention, alcohol and water are taken as solvents to extract the Tongmai oral liquid raw materials together; although the extraction efficiency for the active ingredients is not as good as extraction by using 60% alcohol, the raw material extract prepared by the method is obviously superior to the previous preparation process and the 60% alcohol extract with the highest active ingredient content in pharmacological activity; an unexpected technical effect is achieved; and the Tongmai oral liquid raw material extract is advantageous for the patients suffering cardiovascular and cerebrovascular diseases.

Description

technical field [0001] The invention relates to an extract of raw materials of Tongmai Oral Liquid and its preparation method and application. Background technique [0002] Tongmai Oral Liquid is composed of Danshen, Chuanxiong, and Pueraria lobata. The twentieth volume of the Ministry of Pharmaceutical Standards for Traditional Chinese Medicine Prescriptions. Tongmai Oral Liquid has classic prescriptions, refined medicinal taste, sufficient dosage, and definite curative effect. However, many reasons lead to its unsatisfactory market share, which hinders the pace of growing into a large variety of Chinese patent medicines. [0003] Tongmai Fang has the effect of promoting blood circulation and unblocking the veins, and it is mainly used clinically to treat ischemic cardiovascular and cerebrovascular diseases, arteriosclerosis, coronary heart disease, etc. According to literature reports, the active ingredients of Tongmai Oral Liquid are mainly water-soluble ingredients con...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61P25/00A61K36/537A61K9/08A61K31/58A61K31/192A61K31/352A61P9/10
Inventor 王达宾杨凤梅熊永爱邹俊波苏柘僮姜小东郭华
Owner SICHUAN GOODDOCTOR PHARMA GRP
Features
  • R&D
  • Intellectual Property
  • Life Sciences
  • Materials
  • Tech Scout
Why Patsnap Eureka
  • Unparalleled Data Quality
  • Higher Quality Content
  • 60% Fewer Hallucinations
Social media
Patsnap Eureka Blog
Learn More

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2025 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com