Method for extracting panax notoginseng saponins by using continuous countercurrent ultrasonic extraction combined film technology

Abstract

The invention discloses a method for extracting panax notoginseng saponins by using a continuous countercurrent ultrasonic extraction combined film technology, belonging to the technical field of extraction and separation of plant effective components. The method mainly comprises the following steps of: adding 40-90 percent ethanol having 6-15 times by weight of the pseudo-ginseng crude powder and carrying out continuous countercurrent ultrasonic extraction for 20-120min at a temperature of 20-50 DEG C with the ultrasonic frequency of 20-80KHz; carrying out membrane concentration on filtering liquid by using 1,000-2,500 parts of ultrafiltration membrane or 100-800 parts of nanofiltration membrane at 20-50 DEG C under 0.4-4.1MPa; adding water into the liquid for diluting after the filtering liquid is subjected to pressure reduction and concentrating to be alcohol-free, or directly adding water for diluting; filtering macroporous adsorption resins and eluting with water, and eluting by using 50-90 percent ethanol; carrying out membrane concentration on peralkaline anion resins by using 100-800 parts of nanofiltration membrane under 0.4-4.1MPa; decoloring; carrying out pressure reduction and concentration; and spray-drying. With low-temperature extraction, high extraction ratio, continuous production and high purification ratio, the quality of the product is guaranteed and the method is simple.

Description

technical field [0001] The invention belongs to the technical field of extraction and separation of plant effective components, and in particular relates to a method for extracting total saponins of Panax notoginseng by continuous countercurrent ultrasonic extraction combined with membrane technology. Background technique [0002] Panax notoginseng is a plant of the genus Panax notoginseng of Araliaceae ( Panax notoginseng (Burk.) F. H. Chen) is a rare and precious Chinese medicinal material unique to China. Mainly produced in Wenshan, Yunnan, it is known as the "holy medicine for regulating blood", which can dispel blood stasis and stop bleeding, reduce swelling and relieve pain. For hemoptysis, hematemesis, epistaxis, hematochezia, metrorrhagia, traumatic bleeding, chest and abdomen stabbing pain, swelling and pain from falls. Panax notoginseng saponins are its main active ingredients. Modern pharmacological experiments have proved that panax notoginseng saponins can in...

AI Technical Summary

Problems solved by technology

[0006] The technical problem to be solved by the present invention is to overcome the attenuation of ultrasonic waves in the ultrasonic extraction process of Panax notoginseng saponins in the prior art, and the defects that ultrasonic waves are difficult to effectively conduct, resulting in difficulty in realizing industrialization and forming a large concentration difference, and the extraction efficiency is not high. And the high vacuum and low temperature concentration has high requirements on equipment, the total saponins of Panax notoginseng foams violently, and is easy to flush, which leads to repeated concentration and other shortcomings.

Images