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A compound preparation for treating hypertension and its preparation method

A compound preparation and high blood pressure technology, applied in the field of medicine, can solve the problems of increased side effects, inaccurate clinical drug dosage, influence on drug efficacy, etc., and achieve the effects of less adverse reactions, improved antihypertensive efficacy, and good antihypertensive effect.

Inactive Publication Date: 2011-11-30
JIANGSU JIBEIER PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0015] The product of the present invention overcomes that when propranolol and hydrochlorothiazide are used clinically now, the drug dose is increased to ensure the curative effect when a single drug is used alone, resulting in a significant increase in side effects; Inaccurate use of clinical drug dosage, defects affecting the efficacy of drugs

Method used

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  • A compound preparation for treating hypertension and its preparation method
  • A compound preparation for treating hypertension and its preparation method

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Embodiment 1

[0032] A compound preparation containing the following components:

[0033] Hydrochlorothiazide 25mg

[0034] Propranolol 5mg

[0035] Starch 30mg

[0036] Calcium Sulfate 3mg

[0037] Talc powder 0.5mg

[0038] This embodiment can be made into compound propranolol-hydrochlorothiazide tablets, and the preparation method can adopt the preparation method of common pharmaceutical preparations.

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Abstract

A compound preparation for treating hypertension and a preparation method thereof. The product of the present invention overcomes the obvious increase in side effects caused by increasing the dose of the drug when propranolol and hydrochlorothiazide are used clinically to ensure the curative effect when the drug is used alone; At the same time, because there is no pharmaceutical preparation that meets the combined dosage, the clinical dosage is not accurate, which affects the efficacy of the drug. The combined use of propranolol and hydrochlorothiazide has synergistic and complementary effects in curative effect; the dosage is reduced, the adverse reactions are alleviated, and it is convenient to take and the price is low.

Description

technical field [0001] The invention relates to the technical field of medicine, and discloses a new compound antihypertensive preparation and a preparation method thereof. Background technique [0002] Hypertension is the most common cardiovascular disease and a major public health problem worldwide. my country currently has about 100 million hypertensive patients. According to the epidemiological survey in 1991, the awareness rate of hypertension in my country's urban and rural areas was 36% and 13%, and the treatment rate was 17% and 5%, respectively. The form of hypertension prevention and treatment is quite severe. According to the forecast of WTO, by 2020, non-communicable diseases will account for 79% of the causes of death in my country, among which cardiovascular diseases will take the first place. [0003] Hydrochlorothiazide (Hydrochlorothiazide), the chemical name is 6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide-1,1-dioxide, and the molecular for...

Claims

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Application Information

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IPC IPC(8): A61K31/549A61K31/138A61P9/12
Inventor 吴修艮陈进高瑞银魏福荣朱月华
Owner JIANGSU JIBEIER PHARMA
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