Composition for treating gout containing Angelica Korean angelica extract having xanthine oxidase inhibitory effect and inflammation-inducing enzyme inhibitory effect

A technology of xanthine oxidase and Korean angelica, which is applied in the direction of drug combinations, medical preparations containing active ingredients, anti-inflammatory agents, etc., to achieve the effect of inhibiting activity and reducing the amount of uric acid

Inactive Publication Date: 2011-11-30
KOREA BIO HEALTH
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Problems solved by technology

[0016] However, modern medicine has no cure for gout

Method used

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  • Composition for treating gout containing Angelica Korean angelica extract having xanthine oxidase inhibitory effect and inflammation-inducing enzyme inhibitory effect
  • Composition for treating gout containing Angelica Korean angelica extract having xanthine oxidase inhibitory effect and inflammation-inducing enzyme inhibitory effect
  • Composition for treating gout containing Angelica Korean angelica extract having xanthine oxidase inhibitory effect and inflammation-inducing enzyme inhibitory effect

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Embodiment Construction

[0024] The invention relates to an extract of Angelica sinensis that has a therapeutic effect on gout. The invention utilizes the xanthine oxidase inhibition (XOI) effect to reduce uric acid in blood or urine. In addition, the present invention also relates to an extract of Angelica sinensis that has an inhibitory effect on inflammation-inducing enzymes.

[0025] The Korean angelica extract of the present invention is manufactured according to the method of Korean Patent Application No. 10-2007-45441 previously filed by the present inventors.

[0026] 1. Manufacture of Korean Angelica Extract

[0027] The raw material, Korean angelica, is crushed into a size of 40 mesh or less, dried until the moisture content is less than 5%, and 2 to 4 times the amount of crushed Korean angelica is added to pharmacopoeia ethanol or ethanol, and it is fully extracted after 12 hours filtered and quantified. At this time, the content of the purple flower prostinol and the purple flower prosti...

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Abstract

The invention relates to a composition for treating gout. The composition contains Korean angelica extract which is curative for gout, can inhibit the production of xanthine oxidase (xanthine oxidase), and reduce uric acid in blood or urine, and the invention also relates to a composition for preventing gout inflammation . The composition contains an extract of Angelica sinensis which has an inhibitory effect on the inflammation-inducing enzyme Cox-2. The Korean angelica extract of the present invention is a liquid concentrate whose main components are more than 98% by weight of procurantin and angelica ester of purpurin. For the convenience of human consumption, only water and ethanol are used as solvents during the extraction process of the Korean angelica extract of the present invention. In addition, in order to improve the purity, a refining method using temperature and solubility difference is also adopted.

Description

technical field [0001] The invention relates to a composition for treating gout containing an extract of angelica sinensis which has the effect of treating gout. The present invention reduces uric acid in blood or urine by inhibiting xanthine oxidase. [0002] Furthermore, the present invention relates to a composition for preventing gout inflammation. The composition contains an extract of Angelica sinensis which has an inhibitory effect on the inflammation-inducing enzyme Cox-2. Background technique [0003] The origin of Korean angelica is South Korea, and it is mainly used as a blood tonic in Korean medicine. Recent research results have shown that Korean angelica's indicator substances, purple flower procurantin and purple flower prostinol angelica ester, have the effects of improving blood circulation and anti-helicobacter pylori. The inventors of the present invention have proved through animal experiments that the pure and refined procuredin can inhibit kidney tox...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/232A61P29/00A61K36/00A61K35/00
CPCA61K36/232A61P19/06A61P29/00
Inventor 姜在璿李真暎朴允贞朴宰联金刚民朴珉熙金益焕洪龙槿郑敏洙郑宇植玉善
Owner KOREA BIO HEALTH
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