A transfer chamber with hydrogen peroxide biodecontamination function

Abstract

The invention discloses a transferring cabin with a peroxide biological decontamination function, which consists of a transferring cabin body, a ventilation system, a sterilization circular air returning system, a positive temperature coefficient (PTC) auxiliary heating system, a filtering system, a pneumatic control system, an electric appliance control system, a peroxide generator, and the like, wherein the adequate sterilization of materials to be transferred in different clean areas can be guaranteed, and the problems of the bacteria cross infection caused by the halfway sterilization of materials during the transferring process among different clean areas can be fundamentally solved. In real application, the transferring cabin is particularly suitable for the product with the surface requiring low-temperature and high-temperature sterilization, and has the beneficial effects of no residue after the sterilization and no pollution.

Description

technical field [0001] The invention relates to a transfer cabin, in particular to a transfer cabin with hydrogen peroxide biological decontamination function. Background technique [0002] During the production of sterile pharmaceuticals, reducing or avoiding microbial contamination, and safely sending materials (such as products, packaging materials, containers, etc.) into A / B-level aseptic production areas is one of the most challenging operations. If the outer surface of the material entering the aseptic production area is not sterile, the complex and strict personnel entry procedures and the environmental control requirements of the core area of ​​aseptic production will become meaningless. The technologies currently used mainly include wiping, UV radiation and clean air blowing (air shower) to carry out biological decontamination on the surface of materials, but similar methods are very difficult to meet the requirements of microbial decontamination control in A / B clea...

AI Technical Summary

Problems solved by technology

The 2010 version of GMP adopts new grading standards for the pharmaceutical production environment (clean area), which makes it easy to destroy the A / B-level clean environment by using the traditional material transfer cabin to feed materials, thus bringing potential risks to aseptic production. risk

However, the transfer of materials and biological decontamination using similar methods also have certain defects: on the one hand, some materials with packaging may be damaged after being vacuumized because the packaging bag is not resistant to negative pressure, or Make hydrogen peroxide penetrate the packaging and pollute the material; on the other hand, the cost of the whole system is high, the equipment installation is complicated, and it is difficult to maintain

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