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Drug for controlling bacterial infections in intensive care unit

An intensive care unit and pharmaceutical technology, applied in the field of medicine, can solve problems such as bacterial infection, and achieve the effects of good safety, low pharmaceutical cost and obvious disinfection effect.

Inactive Publication Date: 2012-02-15
孙雪莲
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At the same time, for medical staff, the probability of being infected by germs is greatly increased when working in this working environment

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0010] Weigh 40g of honeysuckle, 10g of Fructus Cnidii, 2g of Sperancifolia, 50g of Panax notoginseng, 2g of Angelica dahurica, 40g of hibiscus bark, 70g of Pulsatilla chinensis, 40g of Radix chinensis and 1000ml of water, and place them in a sealed flask. Heating in a water bath at 30° C. for 5 hours, filtering, collecting the filtrate, concentrating to 500 milliliters, and putting it into a sprayer to make a spray.

experiment example 1

[0011] Experimental example 1: antibacterial test

[0012] Adopt classic filter paper method in this field to carry out bacteriostasis test, wherein:

[0013] 1. Materials

[0014] 1.1 Bacteria to be tested

[0015] Staphylococcus aureus (Staphylococcus aureus) ATCC 25923, Candida albicans (Candida albicans) ACTT 12228 were purchased from China Institute for the Control of Biological Products.

[0016] 1.2 Culture medium

[0017] Nutrient agar and nutrient broth were purchased from Beijing Zhongke Chenyu Experimental Equipment Co., Ltd.

[0018] 1.3 Test method

[0019] Inoculate Staphylococcus aureus and Candida albicans on the nutrient solution plane of the agar plate, and spread evenly and densely when inoculating. Take the aseptic circular filter paper sheet with tweezers, spray the spray prepared in Example 1 until completely wetted, and stick it on the nutrient solution plane of the agar plate inoculated with bacteria. Place the agar plate in a 37°C incubator and i...

experiment example 2

[0022] Experimental example 2: Antibacterial test in the ward

[0023] In the indoor area is equal to 30m 2 Spray 100 milliliters of the spray prepared in embodiment 1 evenly in the ward. 12 hours, 24 hours, and 48 hours after spraying, use the plate sedimentation method to sample, set 3 sampling points, and take 3 points on a diagonal line, that is, 1 point in the middle and 1 point at each end 1m away from the wall , and repeat 10 times. After sampling, culture the culture medium in a 35°C incubator for 48 hours, observe the number of bacterial colonies on the culture medium in a bright place, and calculate the number of bacteria according to the following formula. The amount of bacteria in the air (cfu / m 3 ) = average number of colonies per plate × 50 000 / plate exposure time × plate area. All bacteria were identified in accordance with the "National Clinical Testing Procedures". 12 hours, 24 hours, 48 ​​hours after spraying, the number of bacteria (cfu / m 3 ) were 94,...

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PUM

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Abstract

The invention relates to a drug for controlling bacterial infections in an intensive care unit (ICU), comprising the following ingredients: 3-5 weight portions of honeysuckle flower, 0.5-1.5 weight portions of common cnidium fruit, 0.1-0.3 weight portions of speranskia herb, 4-8 weight portions of pseudo-ginseng, 0.1-0.5 weight portions of dahurian angelica root, 3-7 weight portions of hibiscus syriacus, 5-11 weight portions of Chinese pulsatilla root, and 3-5 weight portions of sessile stemona root. The drug for controlling the bacterial infections in the ICU has the advantages of low cost, good safety, and obvious disinfection effect, and is suitable for large scale clinical use.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a medicament for preventing and treating bacterial infection in an intensive care unit. Background technique [0002] In recent years, the incidence of bacterial infection in the intensive care unit (ICU) has gradually increased, which has attracted more and more attention from clinicians. Different from general respiratory wards, the Intensive Care Unit (ICU) mainly treats various critically ill patients. Due to the critical condition, the patient has a serious internal environment disorder, immune dysfunction, and many chronic underlying diseases, which are prone to various complications. In addition, there are many invasive operations, and most patients have a history of using antibiotics before entering the ICU. The incidence of nosocomial infection in patients was significantly higher than that in general wards. At the same time, for medical staff, the probability of being infected...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A01N65/46A01N65/32A01N65/18A01N65/10A01N65/08A01P1/00
Inventor 董伟
Owner 孙雪莲