Preparation, quality control method and application of composition of active ingredients of bitter herb

A quality control method and active ingredient technology, which can be applied to medical preparations containing active ingredients, drug combinations, plant/algae/fungus/moss components, etc. It can solve problems that affect the separation effect, are difficult to separate out, and have a large production load.
CN102362883AActive Publication Date: 2012-02-29沈阳双鼎制药有限公司
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
沈阳双鼎制药有限公司
Publication Date
2012-02-29

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Abstract

The invention discloses a preparation method, a quality control method and an application of composition of active ingredients ob bitter herb. The composition of the active ingredients of the bitter herb disclosed by the invention mainly comprises cichoric acid and luteolin-7-O-beta-D-glucuronide, and content of the cichoric acid and the luteolin-7-O-beta-D-glucuronide is not less than 80%. An extraction method of the composition comprises that pretreatment is carried out by adopting an enzymatic method, then a supercritical fluid extraction method is adopted, and the obtained extract is respectively subjected to separating, purifying, concentrating and drying by virtue of an AB-8 resin column and a polyamide resin column so as to obtain the composition. Besides, the invention also relates to an application of the composition in preparation of modern bitter herb injection and treatment on coronary heart disease, angor pectoris, myocardial infarction and cerebral infarction and an application of the composition in content determination of the composition of the active ingredients of the bitter herb and quality control of bitter herb medicinal material.
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Description

technical field

[0001] The invention provides a Kudiezi active ingredient composition, and also relates to a preparation method of the composition and an application of the composition, which belong to the technical field of traditional Chinese medicine. Background technique

[0002] Ixeris sonchifolia (Bge) Hance, commonly known as Kudiezi, Gypsophila, etc., is the biennial dry aboveground part of Ixeris sonchifolia (Bge) Hance in the family Asteraceae. It is mainly produced in Northeast my country, North China, etc. land. "Ministry of Health Drug Standards Inner Mongolia Sub-volume" records that the bitter, pungent, cool in nature, has appetizing, detoxifying, bone-setting, and removing swelling effects. Folks are mainly used to treat appendicitis, tonsillitis, and unknown swelling and pain. The research on Kudiezi medicinal materials and preparations has made great progress in recent years. According to literature reports, Kudiezi contains flavonoids, adenosine, lactone ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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