Compound Chinese medicinal preparation for treating ulcerative colitis and preparation method thereof

A technology for ulcerative colitis and preparations, which is applied in the directions of pharmaceutical formulations, medical preparations containing active ingredients, and drug combinations, can solve the problems of many adverse reactions, insignificant curative effects, and single administration methods, and achieves significant curative effects, less adverse effects

Inactive Publication Date: 2012-03-14
INST OF BASIC RES & CLINICAL MEDICINE CHINA ACAD OF CHINESE MEDICAL SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, most of the drugs used to treat ulcerative colitis are immunosuppressants or drugs related to immune function, but they have the disadvantages of many adverse reactions, single administration method, and insignificant curative effect.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0011] A compound traditional Chinese medicine preparation for treating ulcerative colitis, comprising the following traditional Chinese medicine raw materials in the following weight ratio: Codonopsis 8, Radix Astragali 16, Poria cocos 13, Atractylodes macrocephala 8, Woody Fragrant 8, Radix Paeoniae Alba 8, Coptidis 5, Pulsatilla 13, Licorice 5 .

[0012] The preparation method is to wash the above nine medicinal materials, mix them in proportion, add 5 times the total weight of the medicinal materials and decoct them for 3 times, each time for 1 hour, combine the decoctions for 3 times, filter, and concentrate to obtain 60°C It is a liquid extract with a specific gravity of 1.17.

Embodiment 2

[0014] A compound traditional Chinese medicine preparation for treating ulcerative colitis, comprising the following traditional Chinese medicine raw materials in the following weight ratio: Codonopsis 10, Radix Astragali 20, Poria 15, Atractylodes macrocephala 10, Muxiang 10, Radix Paeoniae Alba 10, Coptidis 6, Pulsatilla 15, Licorice 6 .

[0015] All the other are with embodiment 1.

Embodiment 3

[0017] A compound traditional Chinese medicine preparation for treating ulcerative colitis, comprising the following traditional Chinese medicine raw materials in the following weight ratio: Codonopsis 12, Radix Astragali 24, Poria cocos 17, Atractylodes macrocephala 12, Muxiang 12, Radix Paeoniae Alba 12, Coptidis 7, Pulsatilla 17, Licorice 7 .

[0018] The preparation method is to wash the above-mentioned 9 medicinal materials, mix them in proportion, add 5 times the total weight of the medicinal materials and decoct 70% ethanol for 3 times, each time for 1 hour, combine the decoction liquid for 3 times, filter, and Concentrate to obtain a liquid extract with a specific gravity of 1.17 at 60°C.

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Abstract

The invention relates to a compound Chinese medicinal preparation for treating ulcerative colitis. The compound Chinese medicinal preparation comprises the following Chinese medicinal raw materials in weight by percentage: 8-12 percent of codonopsis pilosula, 16-24 percent of astragalus root, 13-17 percent of tuckahoe, 8-12 percent of bighead atractylodes rhizome, 8-12 percent of costus root, 8-12 percent of white paeony root, 5-7 percent of coptis root, 13-17 percent of Chinese pulsatilla root and 5-7 percent of liquoric root. A preparation method of the compound Chinese medicinal preparation comprises the following steps of: cleaning the 9 medicinal materials; mixing in proportion; adding water in an amount which is 5-7 times the total weight of the medicinal materials or ethanol in an amount which is 70 percent of the volume ratio to decoct for 3 times, 1 hour each time; combining decoction for 3 times; filtering; and concentrating to obtain liquid extract with specific gravity of 1.17 at the temperature of 60 DEG C. By adopting the conventional reparation process, the preparation can be prepared into any one pharmaceutically said formulation, such as tablets, capsules, granules, dripping pills, oral liquid, pills, syrup, dispersible tablets and effervescent tablets. The compound Chinese medicinal preparation for treating the depression prepared by the invention has the advantages of obvious curative effect and no adverse effect, and can be applied to treatment of the ulcerative colitis in a large range.

Description

technical field [0001] The invention relates to a traditional Chinese medicine compound preparation for treating ulcerative colitis and a preparation method thereof, belonging to the field of traditional Chinese medicine preparations. Background technique [0002] Ulcerative colitis (Ulcerative Colitis, UC) is a chronic nonspecific inflammatory disease of the colon with unknown etiology. Mainly limited to the large intestine mucosa and submucosa, with abdominal pain, diarrhea, mucus, pus and blood in the stool, tenesmus, etc. as the main symptoms. With the continuous improvement of living standards and changes in diet structure and living habits, the incidence rate is on the rise year by year. It is difficult to cure and easy to relapse after recovery, and even has a certain relationship with the incidence of colon cancer. This disease belongs to the categories of "diarrhea", "long-term dysentery", "rest dysentery" and "intestinal wind" in traditional Chinese medicine. [...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/718A61K36/481A61P1/04
Inventor 吕爱平郑光吕诚姜淼张弛
Owner INST OF BASIC RES & CLINICAL MEDICINE CHINA ACAD OF CHINESE MEDICAL SCI
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