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Apparatus, systems and methods for achieving intravascular, thermally-induced renal neuromodulation

A device and vascular technology, applied to devices, systems and fields for intravascular heat-induced renal neuromodulation, capable of solving problems such as unsatisfactory blood pressure control rate and therapeutic effect

Active Publication Date: 2012-05-02
MEDTRONIC ARDIAN LUXEMBOURG SARL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Despite this diversity of treatment options, rates of blood pressure control and treatment outcomes to prevent worsening of heart failure and chronic kidney disease and their sequelae remain unsatisfactory

Method used

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  • Apparatus, systems and methods for achieving intravascular, thermally-induced renal neuromodulation
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  • Apparatus, systems and methods for achieving intravascular, thermally-induced renal neuromodulation

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Embodiment Construction

[0051] While the disclosure is described in detail and precisely to enable those skilled in the art to practice the disclosed technology, the actual embodiments disclosed are merely exemplary of various aspects of the invention which may embody the same. in other specific structures. While preferred embodiments have been described, details may be changed without departing from the invention as defined in the claims.

[0052] I. Related Anatomy and Physiology

[0053] A) sympathetic nervous system

[0054] The sympathetic nervous system (SNS) is a branch of the autonomic nervous system along with the enteric nervous system and the parasympathetic nervous system. It is always active at a basal level (called sympathetic tone) and becomes more active during stress. Like the rest of the nervous system, the sympathetic nervous system works through a series of interconnected neurons. Sympathetic neurons are often considered part of the peripheral nervous system (PNS), although ...

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Abstract

Apparatus, systems, and methods for achieving thermally-induced renal neuromodulation by intravascular access are disclosed herein. One aspect of the present application, for example, is directed to apparatuses, systems, and methods that incorporate a treatment device comprising an elongated shaft. The elongated shaft is sized and configured to deliver a thermal element to a renal artery via an intravascular path. Thermally-induced renal neuromodulation may be achieved via direct and / or via indirect application of thermal energy to heat or cool neural fibers that contribute to renal function, or of vascular structures that feed or perfuse the neural fibers.

Description

[0001] References to related applications [0002] This application claims the benefit of the following pending applications: [0003] (a) U.S. Provisional Patent Application 61 / 142,128, filed December 31, 2008; [0004] (b) U.S. Patent Application 12 / 495,691, filed June 30, 2009; [0005] (c) U.S. Patent Application 12 / 545,648, filed August 21, 2009; [0006] (d) European Patent Application 09167937.3 filed on 14 August 2009; [0007] (e) European Patent Application 09168202.1 filed on 19 August 2009; and [0008] (f) European patent application 09168204.7 filed on 19.08.2009. technical field [0009] The technology disclosed in this application relates generally to devices, systems and methods for intravascular neuromodulation. More specifically, the technology disclosed herein relates to devices, systems, and methods for intravascular renal neuromodulation via thermogenesis. Background technique [0010] Hypertension, heart failure, and chronic kidney disease are s...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M25/00
CPCA61B2017/00212A61B2018/00404A61N2007/003A61B2018/00434A61B2018/00702A61B2018/00875A61B18/1492A61B2018/00511A61B2018/00797A61B2018/00821A61B90/39A61B18/02A61B18/1206A61B18/18A61B18/24A61B2017/003A61B2018/00172A61B2018/00577A61B2018/00648A61B2018/00791A61M25/0141
Inventor A·吴B·J·克拉克D·扎林司E·赛伊
Owner MEDTRONIC ARDIAN LUXEMBOURG SARL
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