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Pilos antler extraction method and pilos antler extract obtained by same

An extraction method and extraction technology, applied in the field of medicine, can solve the problems of no detailed reports on the activity of velvet antler products, loss of water-soluble components, low extraction rate, etc., to improve the activity of superoxide dismutase, anti-aging prevention and treatment Diseases, effects of high IGF-1 content

Inactive Publication Date: 2012-05-23
INNER MONGOLIA ZHONGLU SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0013] In the traditional processing of velvet antler, velvet antler has to go through steps such as boiling, frying, and drying. Due to the long-term high-temperature cooking, on the one hand, many water-soluble components are lost; on the other hand, the activity of heat-sensitive components such as proteins and peptides completely destroyed
[0014] The water extraction method cannot extract the non-water-soluble components, the selectivity is poor, and the extraction rate is low
Although the alcohol extraction method has high extraction rate and good selectivity, the cost of ethanol is high, which not only pollutes the environment, but also is flammable and explosive, and there are potential safety hazards in production
It is prepared by extraction with organic solvents such as ethanol and ether, which not only greatly destroys the active ingredients of deer antler, but also has low purity and some organic solvents such as ethanol and ether remain.
[0015] Therefore, the traditional processing technology cannot make full use of the active ingredients in velvet, which greatly reduces the application value of velvet and causes waste of resources
[0016] Some patent applications have introduced the research of extracting growth factors from velvet (for example, Chinese patent application publication number CN1603344A), but these methods ignore the utilization of active ingredients other than proteins when extracting velvet polypeptides
[0017] In addition, in the current patent and non-patent literature, there is no detailed report on the activity of the corresponding deer antler products, and there is a lack of experimental data
Moreover, most of the literature does not provide specific data on the yield of velvet antler extract, so it is impossible to judge the quality of its extraction method

Method used

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  • Pilos antler extraction method and pilos antler extract obtained by same
  • Pilos antler extraction method and pilos antler extract obtained by same
  • Pilos antler extraction method and pilos antler extract obtained by same

Examples

Experimental program
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Effect test

Embodiment 125

[0059] Example 125g of fresh velvet antler was washed and cut into pieces, then added 500ml of water, extracted at 200Mpa ultra-high pressure, kept under pressure for 5 minutes, filtered the extract to remove residue, collected transparent and clear liquid, and dried it on a freeze dryer at -45°C to obtain velvet antler Extract lyophilized powder RX1.

Embodiment 225

[0060] Example 225g of fresh velvet antler is washed and cut into pieces, then added with 500ml of water, extracted under 300Mpa ultra-high pressure, kept under pressure for 5 minutes, the extract is filtered to remove the residue, and the transparent and clear liquid is collected and dried on a freeze dryer at -45°C to obtain velvet antler Extract lyophilized powder RX2.

Embodiment 325

[0061] Example 325g of fresh velvet antler was washed and cut into pieces, then added with 500ml of water, extracted under 400Mpa ultra-high pressure, kept under pressure for 5 minutes, the extract was filtered to remove the residue, and the transparent and clear liquid was collected and dried on a freeze dryer at -45°C to obtain velvet antler Extract lyophilized powder RX3.

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Abstract

The invention relates to a pilos antler extraction method and a pilos antler extract obtained by the same. The pilos antler extraction method comprises the following step of: processing pilos antler under superhigh pressure. A pilos antler extraction technology in the invention has the advantages of short extraction time, low energy consumption, high effective component extraction yield, capability of avoiding effective component structure change caused by a thermal effect, and the like. The invention also relates to a composition containing the pilos antler extract obtained by the method and applications of the extract and the composition in preparing medicaments or health foods.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a method for extracting antler and antler extract obtained by the method. Background technique [0002] Antler is the unossified young horn of sika deer or red deer, which grows, ossifies and falls off periodically every year. Deer antler is a traditional Chinese medicine, and its therapeutic effect has been recorded in ancient herbal medicines. Modern medicinal chemical analysis shows that deer antler contains a variety of physiologically active ingredients, which have various effects such as anti-aging, anti-oxidation, improving immunity, and promoting wound healing. The protein and polypeptide substances in the velvet antler tissue account for more than 50% of the total weight. In recent years, a variety of growth factors that have important functions for body growth, development and regulation have been isolated from velvet antler, such as insulin-like growth factor IGF-1 ...

Claims

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Application Information

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IPC IPC(8): A61K35/32A23L1/29A61P17/02A61P37/04A61P39/06A23L33/00
Inventor 刘敬阁董栗曹进国罗春兰朱永亮钱向平
Owner INNER MONGOLIA ZHONGLU SCI & TECH
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