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Preparation method of traditional Chinese medical composition for spur pain elimination

The technology of a composition and a traditional Chinese medicine is applied in the field of bone spur pain-relieving traditional Chinese medicine compositions and the preparation field thereof, which can solve the problems of unsatisfactory curative effect, low cure rate, easy recurrence and the like, and achieve the effect of long-term medication safety and reliability.

Inactive Publication Date: 2013-11-06
NINGXIA BAUHINIA PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] "Guci Xiaotong Capsule" under the item of WS3-B-3944-98 in the 20th volume of "Chinese Medicine Prescriptions" issued by the Ministry of Standards is a pure Chinese medicine preparation. The medicine has been clinically used for many years. A certain curative effect has been achieved; but in the clinical application, we found that its curative effect is not ideal enough, and there are defects that cannot be ignored, such as low cure rate, easy recurrence, and easy moisture absorption and deterioration.

Method used

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  • Preparation method of traditional Chinese medical composition for spur pain elimination
  • Preparation method of traditional Chinese medical composition for spur pain elimination
  • Preparation method of traditional Chinese medical composition for spur pain elimination

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0107] The preparation method of capsule of the present invention:

[0108] Prescription:

[0109]

[0110] Preparation method: the above twelve flavors, Angelica dahurica, coix seed, and angelica are crushed into fine powder; add water to adjust the pH value to 3-4 with hydrochloric acid, boil for two times, and add 8 times for the first time Measure water to extract for 2 hours, add 6 times the amount of water to extract for 2 hours for the second time, combine the decoction, filter, and use the filtrate for later use; Xu Changqing adds 9 times the amount of water to soak for 2 hours, then distill and extract for 4 hours, and refrigerate the distillate until it precipitates White crystals, filter, dry the crystals naturally, set aside, filtrate and medicinal residues, and the rest of the safflower, licorice, Fenugreek, Chuanshanlong, Sunburn, a total of five flavors plus 50% ethanol for reflux extraction twice, the first time add 9 times the amount to extract 2 Add 7 tim...

Embodiment 2

[0112] The preparation method of tablet of the present invention:

[0113] Prescription:

[0114]

[0115]

[0116] Preparation method: the above twelve flavors, Angelica dahurica, coix seed, and angelica are crushed into fine powder; add water to adjust the pH value to 3-4 with hydrochloric acid, boil for two times, and add 8 times for the first time Measure water to extract for 2 hours, add 6 times the amount of water to extract for 2 hours for the second time, combine the decoction, filter, and use the filtrate for later use; Xu Changqing adds 9 times the amount of water to soak for 2 hours, then distill and extract for 4 hours, and refrigerate the distillate until it precipitates White crystals, filter, dry the crystals naturally, set aside, filtrate and medicinal residues, and the rest of the safflower, licorice, Fenugreek, Chuanshanlong, Sunburn, a total of five flavors plus 50% ethanol for reflux extraction twice, the first time add 9 times the amount to extract 2...

Embodiment 3

[0118] The preparation method of granule of the present invention:

[0119] Prescription:

[0120]

[0121] Preparation method: the above twelve flavors, Angelica dahurica, coix seed, and angelica are crushed into fine powder; add water to adjust the pH value to 3-4 with hydrochloric acid, boil for two times, and add 8 times for the first time Measure water to extract for 2 hours, add 6 times the amount of water to extract for 2 hours for the second time, combine the decoction, filter, and use the filtrate for later use; Xu Changqing adds 9 times the amount of water to soak for 2 hours, then distill and extract for 4 hours, and refrigerate the distillate until it precipitates White crystals, filter, dry the crystals naturally, set aside, filtrate and medicinal residues, and the rest of the safflower, licorice, Fenugreek, Chuanshanlong, Sunburn, a total of five flavors plus 50% ethanol for reflux extraction twice, the first time add 9 times the amount to extract 2 Add 7 tim...

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Abstract

The invention relates to a traditional Chinese medical composition for spur pain elimination and a preparation method thereof. The traditional Chinese medical composition is prepared via processing of radix aconiti preparata, radix aconiti kusnezoffi preparata, gentiana macrophylla, radix angelicae, licorice, rhizoma dioscoreae hypoglaucae, dioscorea nipponica makino, semen coicis, prepared rhizoma arisaematis, safflower, angelica, and radix cynanchi panicullati. The medicine has the effect of expelling the wind and eliminating pains and is mainly used for treatment of hyperosteogeny, rheumatoid arthritis and rheumatism. The process is advanced, the formulation is stable, the effects in clinical pharmacodynamic test are improved significantly, the bioavailability is high and no toxic or side effects can be caused.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for eliminating pain due to bone spurs and a preparation method thereof, belonging to the technical field of pharmacy. technical background [0002] "Guci Xiaotong Capsule" under the item of WS3-B-3944-98 in the 20th volume of "Chinese Medicine Prescriptions" issued by the Ministry of Standards is a pure Chinese medicine preparation. The medicine has been clinically used for many years. Obtained certain curative effect; But in the middle of the clinical application, we find that its curative effect is not ideal enough, there is low cure rate, easy to relapse, and easy to absorb moisture and deteriorate, etc. can not be ignored defects. In recent years, we have explored the rich resources of traditional Chinese medicine in the motherland, combined with a large number of traditional Chinese medicine prescription theory and clinical pharmacodynamics research, and applied modern pharmaceut...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8994A61K9/16A61K9/20A61K9/48A61P19/08A61P29/00
Inventor 白锋云张勇罗川
Owner NINGXIA BAUHINIA PHARMA