Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Crystallizing method of aspartame

A technology of aspartame and aspartame, which is applied in the preparation method of peptides, chemical instruments and methods, organic chemistry, etc., can solve the problems of low product quality, blockage, poor crystal form, etc., and improve the product quality. Quality and yield, increased economics, avoidance of polymorphic effects

Active Publication Date: 2012-07-18
MENGZHOU CITY HUAXING BIOCHEM ENG
View PDF1 Cites 6 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the crystal form obtained by this crystallization method is poor, polymorphism is prone to occur, the product quality is low, and clogging will occur in the subsequent centrifugal filtration, which affects the filtration effect

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0009] A method for crystallizing aspartame, comprising cooling the aspartame mother liquor, reducing the temperature of the aspartame mother liquor to 40°C and maintaining the temperature for 0.5h, continuing to cool down to 20°C and maintaining the temperature for 20min, Continue to cool down to 10°C until the aspartame crystals reach the designed precipitation amount.

Embodiment 2

[0011] A method for crystallizing aspartame, comprising cooling the mother liquor of aspartame, reducing the temperature of the mother liquor of aspartame to 45°C and maintaining the temperature for 1.5 hours, continuing to cool down to 30°C and then maintaining the temperature for 30 minutes, Continue to cool down to 10°C until the aspartame crystals reach the designed precipitation amount.

Embodiment 3

[0013] A method for crystallizing aspartame, comprising cooling the aspartame mother liquor, reducing the temperature of the aspartame mother liquor to 42°C and maintaining the temperature for 1 hour, continuing to cool down to 25°C and maintaining the temperature for 25 minutes, continuing Lower the temperature to 10°C, and wait until the aspartame crystals reach the designed precipitation amount.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to a crystallizing method of aspartame. The crystallizing method comprises the following steps of: cooling an aspartame mother solution to lower the temperature of the aspartame mother solution to 40-45 DEG C, and preserving heat for 0.5-1.5 hours; continually lowering the temperature to 20-30 DEG C, and preserving heat for 20-30 minutes; and continually lowering the temperature to 10 DEG C till an aspartame crystal reaches a designed separation amount. According to a new process provided by the invention, the quality of an aspartame crystal form can be improved effectively, the phenomenon of multiple crystal forms is avoided, a subsequent centrifugal operating procedure is facilitated, the product quality is improved, the product yield is increased, and the economic benefit of a plant is further increased.

Description

technical field [0001] The invention relates to a crystallization method of aspartame. Background technique [0002] Aspartame, chemically known as aspartame, is a non-carbohydrate artificial sweetener. It is produced by condensation and amidation of L-phenylalanine with methanol first and then with L-aspartic acid. At room temperature, it is white crystalline powder. Because of its high sweetness and low calorie, aspartame is mainly added to drinks, vitamin lozenges or chewing gum instead of sugar. Many diabetics and dieters use aspartame as a sugar substitute. [0003] The crystallization process of aspartame is an important process in the production of aspartame, which has an important impact on the output and quality of aspartame and the economic benefits of the factory. The commonly used crystallization method of this production process is cooling crystallization, that is, the temperature of the aspartame mother liquor is lowered from about 65°C to 10°C, and the cry...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): C07K5/075C07K1/14
Inventor 周延红文铁军马秋红
Owner MENGZHOU CITY HUAXING BIOCHEM ENG
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com