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Root-securing and panting-calming granule and preparation process thereof

A granule and anti-asthmatic technology, applied in the field of Guben Pingchuan granules and its preparation technology, can solve the problems of insufficient drug effect research, single dosage form, etc.

Inactive Publication Date: 2012-08-22
辽宁省中医药研究院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Aiming at the problems of single dosage form and insufficient efficacy research in traditional Chinese medicine used in the treatment of asthma, Guben Pingchuan Granules were made on the basis of the in-house preparations used in our hospital for many years. After pharmacological and clinical studies, its efficacy was verified. Effectiveness and Safety

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] Drug composition: Sunburned ephedra 6g, psoralen 6g, almond 6g, heterophylla 10g, perilla 10g, loquat leaf 10g, Sichuan lily 10g, fairy spleen 10g.

[0040] Preparation process: Take the above 8 flavors, add 6 times the amount of water to extract twice, extract for 1.0 hours each time, filter, combine the filtrate, concentrate to a thick paste with a relative density of 1.31 (60°C), add 1.3 times the amount of dextrin, and stir well , add 80ml of 95% ethanol, granulate, dry, granulate, subpackage, vested. Out of 30g finished product.

[0041]

Embodiment 2

[0043] Drug composition: Sunburned ephedra 3g, psoralen 5g, almond 5g, heterophylla 10g, perilla 8g, loquat leaf 5g, Sichuan lily 15g, fairy spleen 10g.

[0044] Preparation process: Take the above 8 flavors, add 7 times the amount of water to extract twice, extract for 1.5 hours each time, filter, combine the filtrate, concentrate to a thick paste with a relative density of 1.30 (60°C), add 1.2 times the amount of dextrin, and stir well , add 50ml of 95% ethanol, granulate, dry, granulate, subpackage, vested.

[0045]

Embodiment 3

[0047] Drug composition: Sunburned ephedra 9g, psoralen 15g, almond 8g, heterophylla 10g, perilla 5g, loquat leaf 10g, Sichuan lily 5g, fairy spleen 15g.

[0048] Preparation process: Take the above 8 flavors, add 6 times the amount of water to extract twice, extract for 1.0 hours each time, filter, combine the filtrate, concentrate to a thick paste with a relative density of 1.32 (60°C), add 1.5 times the amount of dextrin, and stir well , add 100ml of 95% ethanol, granulate, dry, granulate, subpackage, vested. Out of 30g finished product.

[0049]

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PUM

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Abstract

The purpose of the invention is to provide a Chinese patent medicine of a root-securing and panting-calming granule for treating deficiency-type wheezing during bronchial asthma attack phases. Aiming at the problems of single dosage form and insufficient drug effect research for current applications of traditional Chinese medicines in asthma treatment, the root-securing and panting-calming granule is prepared based on a hospital preparation used in our hospital for years, and the effectiveness and safety of the granule are verified through pharmacological research and clinical research.

Description

technical field [0001] The invention relates to a Chinese patent medicine for treating deficiency syndrome in the attack stage of bronchial asthma. Background technique [0002] Bronchial asthma (hereinafter referred to as asthma) is an allergic inflammatory disease characterized by airway hyperresponsiveness (AHR) involving a variety of cells, cytokines and inflammatory mediators. Due to the intricate pathogenesis of asthma, it is still not fully understood. At present, western medicine studies on the pathogenesis of asthma mainly focus on the theory of airway inflammation, the theory of immunity and allergy, the mechanism of airway nerve regulation, and the genetic mechanism. Asthma can occur at any age, has an obvious family history, has the characteristics of recurrent attacks, and has a long course of disease. If it is not controlled in time, it may cause serious complications and even cause death. Moreover, its morbidity and mortality are increasing day by day. It i...

Claims

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Application Information

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IPC IPC(8): A61K36/8966A61K9/16A61P11/06
Inventor 郭振武乔世举于雪峰甘雨马进王祺李显华姚明陈贺徐月英张宏石绍顺付东升李丁蕾关玉娟于国强李明飞宋达夫周淑梅
Owner 辽宁省中医药研究院
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