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Capsule for treating urinary system diseases and preparation method thereof

A technique for urinary system diseases and traditional Chinese medicine capsules is applied in the field of capsules for the treatment of urinary system diseases and the field of preparation thereof, which can solve the problems of unreduced incidence rate, recurrence rate and reinfection rate of urinary system infection, unsatisfactory clinical treatment efficiency, and toxic and side effects. And other issues

Active Publication Date: 2013-01-02
贵州弘泽制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the main measure of Western medicine to treat urinary tract infections is the use of antimicrobial drugs. The long-term use of antibiotics for recurrent chronic urinary tract infections is not effective. In fact, it does not reduce the incidence, recurrence and reinfection rates of urinary tract infections. , and often cause toxic side effects and drug resistance
Through research, it is found that the traditional Chinese medicine capsule (hereinafter referred to as the comparative traditional Chinese medicine capsule) made of Sijihong as the main material, Tween-80, propylene glycol and polyethylene glycol 400 as auxiliary materials in a certain proportion is effective in the treatment of urinary system diseases. The curative effect is good, but the effective rate of clinical treatment is still not ideal

Method used

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  • Capsule for treating urinary system diseases and preparation method thereof
  • Capsule for treating urinary system diseases and preparation method thereof
  • Capsule for treating urinary system diseases and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Weigh 3000g of Sijihong, 2000g of bristle grass and 1000g of Phellodendron cortex, cut into sections, add water to decoct 3 times, each time add 8 times the water of the quality of Sijihong, decoct for 60 minutes for the first time, and decoct for 80 minutes for the second time , followed by merging the liquid medicines, standing overnight, filtering through ceramic membranes, depressurizing the filtrate under the conditions of a vacuum of 0.06Mpa and a temperature of 80°C, and then concentrating to a relative density of 1.20g / cm3 at 60°C 3 The thick paste of the above-mentioned drug raw material extract is subjected to microwave drying, pulverization, and crossing 100 mesh sieves to obtain about 400g of the drug raw material extract; for subsequent use; add 4g of Tween-80, 24g of propylene glycol, and 372g of polyethylene glycol to the above-mentioned drug raw material extract. Alcohol-400, mixed, colloid milled evenly, made into soft capsules with the standard of 0.8g ...

Embodiment 2

[0026] Weigh 3500g of Sijihong, 2500g of bristle grass and 1200g of Phellodendron cortex, cut into sections, add water to decoct 3 times, each time add 10 times the quality of Sijihong, decoct for 60 minutes for the first time, and decoct for 80 minutes for the second time , followed by combining the liquid medicines, standing overnight, filtering with ceramic membranes, depressurizing the filtrate under the conditions of vacuum degree 0.07Mpa and temperature 80°C, and then concentrating to 60°C when the relative density is 1.25g / cm 3 The thick paste, then carry out microwave drying, pulverization, cross 110 mesh sieves, obtain about 500g medicinal raw material extract, standby; Add the propylene glycol of 8g of Tween-80, 28g, the polyethylene glycol of 364g- 400, mixing, colloid mill grinding evenly, making soft capsules with the standard of 0.8g per grain, to get final product.

Embodiment 3

[0028] Take by weighing Sijihong 3700g, bristle grass 2700g and 1300g Phellodendron cortex, cut into sections, add water and decoct 3 times, add 10 times of the water of the described Sijihong quality each time, decoct for 80 minutes each time, then pass successively through merging medicinal liquid, static Place overnight, filter with ceramic membrane, depressurize the filtrate according to the conditions of vacuum degree 0.07Mpa and temperature 80°C, and then concentrate to 60°C when the relative density is 1.28g / cm 3 The thick paste is then microwave-dried, pulverized, and passed through a 150-mesh sieve to obtain about 600g of the drug raw material extract, which is set aside; add 15g of Tween-80, 60g of propylene glycol, and 425g of polyethylene glycol- 400, mixing, colloid mill grinding evenly, making soft capsules with the standard of 0.8g per grain, to get final product.

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Abstract

The invention relates to a capsule for treating urinary system diseases and a preparation method thereof. The capsule is a traditional Chinese medicine capsule for treating urinary system infection and inflammations. The preparation method comprises that 30 to 50 parts by mass of Polygonum capitatum D.Don, 20 to 40 parts by mass of all-grass of maidenhair, 10 to 20 parts by mass of amur corktree bark and 4 to 6 parts by mass of auxiliary materials are orderly subjected to extraction, drying, crushing, blending and filling. The capsule for treating urinary system diseases has the effects of clearing away heat and purging pathogenic fire, alleviating water retention and treating stranguria, diminishing inflammation and swelling, and eliminating dampness and inducing diuresis, has good treatment effects on urinary system infection and inflammations caused by stagnation of dampness-heat, is safe and effective, has controllable quality, avoids repeated attack, has no obvious toxic and side effects, does not cause drug resistance, and has a low cost and a high clinical popularization value.

Description

technical field [0001] The invention relates to a capsule for treating urinary system diseases and a preparation method thereof, in particular to a traditional Chinese medicine capsule for treating urinary system infection and inflammation and a preparation method thereof. Background technique [0002] Urinary system infection and inflammation are common clinical diseases, including symptoms such as frequent urination, urgency, urethral burning, yellow and red urine, lower abdomen distension, pelvic inflammatory disease, urethritis, cystitis, pyelonephritis, vaginitis, urinary tract stones, prostatitis , Prostatic hyperplasia and other diseases. With the change of people's lifestyle and the acceleration of the pace of life, the incidence of urinary system diseases is increasing year by year, and this disease is not only difficult to treat, but also may cause repeated attacks due to untimely treatment or improper treatment methods. Low immunity, long-term suffering from infl...

Claims

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Application Information

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IPC IPC(8): A61K36/756A61K9/48A61P13/00
Inventor 罗泽华周月波
Owner 贵州弘泽制药有限公司
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