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Universal holder for large and mouse breathing masks

A technology of breathing mask and fixer, which is applied in veterinary equipment, medical science, etc., can solve the problems of low success rate of chronic myocardial ischemia model preparation, not well solved, and long experiment period, so as to achieve easy promotion and Ease of application, operation, and guaranteed stability

Inactive Publication Date: 2015-10-21
FOURTH MILITARY MEDICAL UNIVERSITY
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  • Abstract
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  • Claims
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Problems solved by technology

However, a large number of mechanism studies and drug studies are based on acute myocardial ischemia, but there are relatively few studies on chronic myocardial ischemia. One of the main reasons is that the success rate of chronic myocardial ischemia model preparation in mice is low, High mortality rate and long experimental period have become the bottleneck problems restricting the research of chronic myocardial ischemia, which have not been well solved for a long time

Method used

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  • Universal holder for large and mouse breathing masks
  • Universal holder for large and mouse breathing masks
  • Universal holder for large and mouse breathing masks

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Embodiment Construction

[0022] 1. Hemp anhydride: 3% pentobarbital sodium (40-50mg / kg) was used for intraperitoneal injection, and after the rat was anesthetized, it was fixed on the rat operating table in a supine position, and the limbs were connected to the heart conduction line for ECG. guardianship.

[0023] 2. How to install the mandibular fixator: put the opening of the mandibular fixer into the neck along the lower edge of the bilateral mandibular angle of the mouse, adjust the tightness and insert it into the entrance of the universal fixer base, and pass through the bilateral The locking device is fixed (see figure 2 ). The thoracic surgical area was clipped and disinfected.

[0024] 3. Installation and fixation of the breathing mask: insert the large and mouse breathing mask pole into the mask holder entrance on the upper part of the universal holder, and fix it through the lockers on both sides; press the slide groove unlock button, push the mask forward to fix it After the device is ...

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Abstract

Disclosed is a general fixing device for breathing masks of rats and mice. The breathing masks of the rats and the mice play an important role in preparation of a chronic myocardial ischemia model and solve the bottleneck problem of preparation of the model, by means of the breathing masks, the survival rate of the prepared model is increased from 40% to over 90%, and work efficiencies are improved by over 4 times; and the fixing device is specially designed and manufactured for fixing the breathing masks of the rats and the mice and is one of series experimental study results, and reports about fixing devices for the breathing masks are absent at home and abroad. The general fixing device for the breathing masks is composed of a base and a mask fixing portion (shown as diagram one), wherein the base is composed of a jaw fixing device inlet (1), a jaw fixing device locker (2), a sliding slot (3) and an operating table fixing hole (4); and the mask fixing portion is composed of a breathing mask rod inlet (5), a mask rod locker (6) and a sliding slot unlocking button (7). The fixing device has the advantages of being convenient to operate, popularize and apply, stable in performance and wide in market application prospect and the like.

Description

technical field [0001] This fixer is specially designed and manufactured for fixing the breathing masks of big and mouse. The development and application of breathing masks for rats and mice can well solve the bottleneck problem in the preparation of chronic myocardial ischemia models in mice and rats (the breathing mask for rats has been authorized for an invention patent, the patent number is: ZL 200810150927.8), suitable for In the field of medical cardiovascular medicine, basic research, applied research, research on the mechanism of drug action and evaluation of therapeutic effects based on the platform of acute and chronic myocardial ischemia in mice and mice. Background technique [0002] Myocardial ischemia, myocardial infarction and heart failure are one of the major killers of human diseases, which have already attracted great attention from the medical circles at home and abroad, and their research is also constantly deepening, and gratifying achievements have bee...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61D7/04
Inventor 裴建明王跃民迟素敏马恒郭海涛樊荣李娟张淑苗冯娜
Owner FOURTH MILITARY MEDICAL UNIVERSITY