Reconstruction method of dynamic positron emission tomography (PET) images based on particle filter
An image reconstruction and particle filter technology, applied in the field of PET imaging, can solve the problems of low information utilization, inability to load prior physiological information, and low reconstruction accuracy
Active Publication Date: 2015-01-28
ZHEJIANG UNIV
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[0006] However, the above algorithms have some defects in the real-time dynamic reconstruction of PET. Some of them cannot adapt to the huge amount of data collected in dynamic PET imaging, resulting in low reconstruction accuracy or too long time-consuming. The experimental physiological information is loaded into the reconstruction, so that the information utilization rate of the reconstruction is low
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[0036]In order to describe the present invention more specifically, the PET image reconstruction method of the present invention will be described in detail below in conjunction with the accompanying drawings and specific embodiments.
[0037] Such as figure 1 As shown, a dynamic PET image reconstruction method based on particle filter includes the following steps:
[0038] (1) Collect coincidence counts and establish state space equations.
[0039] Use detectors (positron emission tomography scanners) to detect human tissues injected with radioactive substances, collect multiple sets of coincidence counts corresponding to different times, and each set of coincidence counts corresponds to a frame of PET images; The radioactive signal is processed by the coincidence and acquisition system to form the original projection line, which is stored in the computer in the form of a sinogram; after various corrections are made to the original collected sinogram data, the coincidence co...
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The invention discloses a reconstruction method of dynamic PET images based on particle filter. The reconstruction method includes collecting coincidence counting and constructing a state space equation, performing particle sampling on a voxel and evaluating a prior concentration value of the voxel, calculating a particle weight value, performing resampling calculation, evaluating a particle concentration true value and a particle weight true value through iteration, and evaluating a voxel value and traversing and reconstructing each frame of the PET images. According to the reconstruction method, data statistical characteristics and physiological properties of the PET are combined for reconstructing the PET dynamic images through the state space equation and the particle filter, filtration to noise is strengthened effectively, the reconstruction accuracy of the dynamic PET image is improved, the dynamic PET images can be better restored, so that reconstruction results have more use values in the medical field.
Description
technical field [0001] The invention belongs to the technical field of PET imaging, and in particular relates to a dynamic PET image reconstruction method based on particle filter. Background technique [0002] The full name of PET is Positron emission tomography, also known as positron emission tomography, which is a medical imaging technology based on nuclear physics and molecular biology. In particular, it provides an effective basis for the detection and prevention of tumors. PET essentially images the concentration distribution of drugs in the patient's body. The radioisotope-labeled drugs injected into the patient's body enter the circulatory system through the blood, and these substances will form a certain concentration distribution in various tissues and organs in the human body. Due to the short half-life of radioactive isotopes and their extreme instability, they will soon decay, and the positrons released during the decay will undergo an annihilation reaction wi...
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IPC IPC(8): G06T11/00
Inventor 刘华锋于行健胡正珲
Owner ZHEJIANG UNIV