Blood coagulation quality control product and preparing method thereof

A coagulation quality control and coagulation technology, which is applied in the field of quality control of clinical coagulation test items, can solve the problems of high price, and achieve the effect of low raw material cost, stable coagulation factors, and easy access
CN103163307BActive Publication Date: 2015-06-03SHANGHAI SUNBIO TECH
8 Cites 0 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
SHANGHAI SUNBIO TECH
Publication Date
2015-06-03

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

The invention relates to the field of quality control of a clinical blood coagulation inspection item, and in particular provides to a method for preparing a quality control product which can be used for simultaneously carrying out PT (Prothrombin Time), APTT (activated partial thromboplastin time) and FIB (fibrinogen) blood coagulation inspection items through animal blood plasma. The method comprises the steps of mixing the animal blood plasma according to an appropriate rate, adding or removing the FIB, adding proper amount of blood plasma buffer solution contacting a stabilizing agent so as to enable detecting results of mixed blood plasma PT, APTT and FIB to be in the range of a blood coagulation indicator of a normal person, drying and cooling, thus obtaining the product. The blood coagulation quality control product prepared by the method provided by the invention has good sensibility to variation of a detection reagent, has high stability and meets the quality control requirement of the clinical blood coagulation inspection item.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The invention relates to the field of quality control of clinical blood coagulation test items, in particular to a method for preparing a quality control product that can be used for PT, APTT and FIB blood coagulation test at the same time by using animal plasma and the prepared blood coagulation quality control product. Background technique

[0002] Mammalian blood coagulation is a complex physiological and biochemical metabolic process. Its essence is to convert liquid fibrinogen in plasma into solid cross-linked fibrin through a series of enzymatic reactions, referred to as blood coagulation. The multiple materials that participate in each chain reaction are called blood coagulation factors, and their chemical essence, except calcium ion, the great majority is protein. The coagulation process can be divided into three basic steps: the formation of prothrombin activator, the activation of prothrombin and the generation of fibrin. According to the di...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More