Preparation method of active polysaccharide peptide with protective effect on alcoholic liver injury and compound of active polysaccharide peptide

A technology of alcoholic liver injury and protective effect, applied in the preparation method and compounding field of active polysaccharide peptide

Inactive Publication Date: 2013-07-24
SHENYANG AGRI UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Combining the two extraction processes organically, and finding out a new polysaccharide-peptide compound drink process and its derivative new products, can produce a compensatory effect on corn peptide to promote alcohol metabolism, which has not yet been done at home and abroad research report

Method used

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Experimental program
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Embodiment Construction

[0018] Preparation of active polysaccharide peptide:

[0019] 1. Wash and remove the flesh of the fresh bitter gourd, slice and dry in a 50°C oven; crush the dried bitter gourd slices into dry powder (through a 100-mesh sieve). Weigh 100 grams of balsam pear dry powder, add cell wall degrading enzyme solution (containing 0.5% cellulase, 0.8% pectinase, surplus 0.05mol / L, pH4.5) according to the ratio of solid-liquid ratio of 1:40 Citric acid buffer) 4L was extracted in a water bath at 50°C for 3 hours, and the extract was centrifuged at 4500r / min for 10 minutes to obtain 3.5L of supernatant, which was concentrated under reduced pressure to 350ml, precipitated with 3 times the volume of absolute ethanol, and then placed in Centrifuge at 7000r / min for 10min, collect 100ml of precipitated redissolved polysaccharide solution, add 15g of activated carbon to it, decolorize for 10min, and then centrifuge at 10000r / min for 3min to clarify the polysaccharide solution.

[0020] 2. Weig...

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Abstract

The invention provides a preparation method of active polysaccharide peptide with protective effect to alcoholic liver injury and a compound of the active polysaccharide peptide. The method is characterized by comprising the following steps of: preparing polysaccharide peptide by processes of smashing, alcohol precipitation, degreasing, centrifugation, composite enzymatic hydrolysis, centrifugal separation and the like on fresh balsam pear and maize yellow powder, wherein the proportion of polysaccharide to maize peptide is 1:3; and then regulating flavor by malic acid and xylitol to obtain a polysaccharide peptide alcohol dispelling and liver protecting oral liquid. on the basis that alanine and leucine concentration in blood is improved to generate stable NAD+ so as to effectively reduce ethanol concentration in blood, the inhibition ratio of hydroxyl radicals reaches 100%, and liver cell mitochondria is prevented from being oxidized and injured. The process of the active polysaccharide peptide is simple and easy to operate; and the active polysaccharide peptide has high extraction content, high absorption rate, strong function and the like; therefore, great social and economic benefits are achieved.

Description

technical field [0001] The invention relates to a biological product, in particular to a preparation method and compounding of an active polysaccharide peptide which has a protective effect on alcoholic liver injury. Background technique [0002] Alcoholic liver disease (ALD) caused by alcoholic liver injury occurs frequently in Europe and the United States. With the development of my country's economy and changes in people's lifestyles, the incidence of ALD in my country is increasing year by year. In the food culture of our country, there must be drinking when there is a banquet, and drinking is often drunk. Excessive drinking can cause liver damage. Alcoholic liver disease is a common disease in developed countries, but it has also reached a level that cannot be ignored in my country in recent years. According to statistics, the incidence of alcoholic liver injury among alcoholics in my country is about 20%. Alcoholic liver disease has become the second role after viral ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L1/09
Inventor 陈红漫涂年影周锐丛咪阚国仕任大明
Owner SHENYANG AGRI UNIV
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