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Sublingual cigarette and preparation method thereof

A technology of sublingual tobacco and nicotine, applied in the field of sublingual tobacco and its preparation, can solve the problems of dental caries side effects, oral ulcers, unsuitable for long-term use of diabetics, etc., achieve good hardness and disintegration, and high bioavailability , protective and healing effects

Active Publication Date: 2013-09-11
中国烟草总公司山东省公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

These inventions have increased the number of new types of tobacco products in my country and enriched the choices of consumers. However, due to the high proportion of sugar substances added in these inventions, such as sucrose, honey, fructose, glucose, etc., they are not suitable for long-term use by diabetics. At the same time, the existing products are all buccal products. This type of snus is in close contact with the oral cavity and teeth for a long time, which may cause oral ulcers and serious side effects of dental caries.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Ingredients: nicotine 0.3%, mung bean starch 65%, calcium sulfate 5%, sodium alginate 15%, xylitol 10%, stevioside 3%, licorice zinc 0.8%, vitamin C 0.3%, menthol 0.6% .

[0022] Preparation method: Add water three times its mass to sodium alginate, heat and stir to dissolve sodium alginate to form 25% sodium alginate glue; mix mung bean starch, calcium sulfate, xylitol, stevioside, licorice zinc and Mix vitamin C evenly, add 25% sodium alginate mucilage to make a soft material, extrude the granules with a 14-mesh sieve, dry at 70-80°C for 2 hours, and granulate with a 12-mesh sieve for later use. After dissolving nicotine and menthol with 70% ethanol, spray evenly on the prepared granules. Stir and mix well, and place it in an airtight place for 3 hours, so that the active ingredients can penetrate evenly, so as to prevent the phenomenon of splitting during tablet compression. Squeeze it into tablets with a punching machine. The weight of each sublingual cigarette i...

Embodiment 2

[0025] Raw material formula: nicotine 0.4%, mung bean starch 70%, calcium sulfate 4.8%, sodium alginate 10%, xylitol 12%, perillaldehyde 2%, licorice zinc 0.5%, vitamin B0.2%, vitamin C0. 1%.

[0026] Preparation method: Mix mung bean starch, calcium sulfate, sodium alginate, xylitol, perillaldehyde, licorice zinc, vitamin B, and vitamin C, spray with appropriate amount of water, start the stirring granulator to prepare granules, and dry the granules at 60°C 2h, through a 20-mesh sieve, so that the particles that can pass through the 20-mesh sieve account for 1 / 3 of the total, and there is no fine powder that passes through the 100-mesh sieve. After dissolving nicotine with 45% ethanol, spray evenly on the prepared granules. Stir and mix well, place in airtight place for 3 hours, make the active ingredients permeate evenly, and press into tablets with a punching machine, that is to say. The weight of each sublingual cigarette is 270 mg.

[0027] The sublingual cigarette is ...

Embodiment 3

[0029] Raw material formula: nicotine 0.2%, mung bean starch 75%, calcium sulfate 4.5%, sodium alginate 10%, mogroside 5%, trilobatin 3%, licorice zinc 0.7%, folic acid 0.6%, mint oil 1%.

[0030] Preparation method: add water three times its mass to sodium alginate, heat and stir to dissolve sodium alginate to form 25% sodium alginate glue; mix mung bean starch, calcium sulfate, mogroside, trilobatin, licorice zinc and Mix the folic acid evenly, add 25% sodium alginate mucilage to make a soft material, extrude the granules with a 14-mesh sieve, dry at 70-80°C for 2 hours, and granulate with a 12-mesh sieve for later use. After dissolving nicotine and peppermint oil with 70% ethanol, spray evenly on the prepared granules. Stir and mix well, and place it in an airtight place for 3 hours, so that the active ingredients can penetrate evenly. Squeeze it into tablets with a punching machine. The weight of each sublingual cigarette is 300mg.

[0031] The sublingual cigarette is whi...

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Abstract

The invention discloses a sublingual cigarette and a preparation method of the sublingual cigarette and belongs to the field of novel tobacco products. The sublingual cigarette comprises, by mass, 0.01%-6% of nicotine, 3%-15% of non-carbonhydrate sweet substances, 5%-35% of sodium alginate, 45%-80% of green bean starch, 3%-8% of calcium sulphate, 0.5%-3% of licorzince, 0.2%-0.8% of vitamin and 0%-0.6 of menthol (or peppermint oil). Compared with existing novel tobacco products, the sublingual cigarette has the advantages that rapid sublingual dissolution can be achieved, onset is fast and no residue exists; the sweetness of the sweet substances is high, the dosage is small, and the cost is saved; the physiological needs of a consumer can be met, and the functions of decayed tooth prevention and oral ulcer can be achieved; elevated blood glucose can not be caused, and the sublingual cigarette is applicable to long-term use of the diabetic population.

Description

technical field [0001] The invention relates to the field of novel tobacco products, in particular to sublingual tobacco and a preparation method thereof. Background technique [0002] New tobacco products have been widely recognized by tobacco consumers around the world because they overcome the shortcomings of traditional tobacco products (including cigarettes and cigars), produce no smoke when used, and provide a physical experience similar to smoking . [0003] The "Snus" produced by the American Reynolds Company, which is currently popular in the European and American markets, is a small bag containing ground moist tobacco, similar to a tea bag. Users place the pouch between their upper lip and gums for the same sensation as smoking. In India, Gutka, as a dry, easy-to-carry non-traditional chewing tobacco, is favored by consumers, and it meets the needs of modern people's fast-paced lifestyle. [0004] In recent years, many new tobacco product invention patents have ...

Claims

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Application Information

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IPC IPC(8): A24B15/16A24B15/18
Inventor 王永平纪立顺朱友别振英蔚亦沛任呼博陈玉松张福民陆伟刘敏
Owner 中国烟草总公司山东省公司
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