Unlock instant, AI-driven research and patent intelligence for your innovation.

Chinese medicinal composition capable of clearing heat and freeing lung as well as ventilating lung and resolving phlegm and preparation method thereof

A technology for resolving phlegm, relieving cough, clearing heat and clearing lungs, which is applied in drug combination, drug delivery, and medical formula, and can solve the problems of long extraction process cycle, inconvenient taking and carrying, and susceptibility to microbial contamination, etc. Dispersion and dissolution speed, fast drug onset, effect of reducing process production cycle

Inactive Publication Date: 2013-12-18
BEIJING ASIA EAST BIO PHARMA CO LTD
View PDF4 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Chuanbei Pipa Syrup is an oral syrup-like pure Chinese medicine preparation for treating symptoms such as wind-heat invading the lung, internal stagnation of fire, yellow sputum or unpleasant spitting, sore throat, chest tightness and pain, cold cough and chronic bronchitis. After years of clinical verification, the quality is stable and the curative effect is definite. It is a commonly used pharmaceutical preparation for clinical and family use to treat the above diseases. However, the problem of Chuanbei loquat syrup as an oral liquid preparation is that it is easily contaminated by microorganisms during storage and has low drug content. The dosage is large, it is inconvenient to take and carry, etc., and the extraction process of Fritillaria fritillaria in the existing technology has a long cycle and cumbersome operation, which is not conducive to large-scale industrial production

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Chinese medicinal composition capable of clearing heat and freeing lung as well as ventilating lung and resolving phlegm and preparation method thereof
  • Chinese medicinal composition capable of clearing heat and freeing lung as well as ventilating lung and resolving phlegm and preparation method thereof
  • Chinese medicinal composition capable of clearing heat and freeing lung as well as ventilating lung and resolving phlegm and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0102] API:

[0103] Chuan Fritillaria 45g, Campanulaceae 45g, Loquat Leaf 300g, Menthol 0.34g.

[0104] Preparation Process:

[0105] Pulverize Fritillaria sichuanensis into coarse powder, soak in 6 times the amount of 75% ethanol for 6 hours, then use reverse reflux extraction method for reflux extraction for 8 hours, recover the ethanol from the extract, and prepare the medicinal liquid for later use; add bellflower and loquat leaves to decoct twice, 2.5 hours for the first time, 2 hours for the second time, combine the decoction, filter, add the above-mentioned Fritillaria chinensis ethanol extract and continue to concentrate to a thick paste with a relative density of 1.30-1.35 (50°C), and dry to obtain the composition extract .

[0106]The composition extract is pulverized into fine powder, and menthol is encapsulated with β-cyclodextrin, and the composition extract powder of 70g and the menthol β-cyclodextrin inclusion complex of 9g are mixed with the effervescent dis...

Embodiment 2

[0108] API:

[0109] Chuan Fritillaria 70g, Campanulaceae 30g, Loquat Leaf 450g, Menthol 0.2g.

[0110] Preparation Process:

[0111] Pulverize Fritillaria sichuanensis into coarse powder, add 8 times of 65% ethanol to soak for 6 hours, then use reverse reflux extraction method for reflux extraction for 6 hours, recover ethanol from the extract, and prepare the medicinal liquid for later use; add platycodon grandiflorum and loquat leaves to decoct 3 times, 2.5 hours for the first time, 2 hours for the second and third times, combine the decoction, filter, add the ethanol extract of Fritillaria sichuanensis and continue to concentrate to a thick paste with a relative density of 1.30-1.35 (50°C), dry it Obtain the composition extract.

[0112] The composition extract is pulverized into fine powder, and menthol is encapsulated with β-cyclodextrin, and the composition extract powder of 50g and the menthol β-cyclodextrin inclusion complex of 8g are mixed with the effervescent dis...

Embodiment 3

[0114] API:

[0115] Chuan Fritillaria 20g, Campanulaceae 80g, Loquat Leaf 250g, Menthol 0.75g.

[0116] Preparation Process:

[0117] Grind Fritillaria sichuanensis into coarse powder, add 4 times the amount of 80% ethanol to soak for 6 hours, then use reverse reflux extraction method for reflux extraction for 10 hours, recover ethanol from the extract, and prepare the medicinal liquid for later use; decoct platycodon grandiflorum and loquat leaves twice with water, 2.5 hours for the first time, 1.5 hours for the second time, combine the decoction, filter, add the above-mentioned Fritillaria chinensis ethanol extract and continue to concentrate to a thick paste with a relative density of 1.30-1.35 (50°C), and dry to obtain the composition extract .

[0118] The composition extract is pulverized into fine powder, and menthol is encapsulated with β-cyclodextrin, and the composition extract powder of 100g and the menthol β-cyclodextrin inclusion complex of 12g are mixed with t...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention provides a chuanbei pipa syrup effervescent tablet. The chuanbei pipa syrup effervescent tablet is quick to disintegrate, easy to take, fast in effect and high in bioavailability, can improve clinical curative effect and is especially applicable to children, the aged and a patient who has difficulty in swallowing a pill, a seasoned effervescent tablet is better in taste, a good medicine is not bitter any more, and a patient can accept with pleaser. The invention also provides a fritillaria cirrhosa extraction process, a production period is shortened, and industrialization production is facilitated.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for clearing away heat, promoting lung, resolving phlegm and relieving cough and a preparation method thereof, belonging to the field of preparations. Background technique [0002] The prior art discloses the composition and preparation process of Chuanbei loquat syrup [0003] Chuan Fritillaria Fluid Extract 45ml Bellflower 45g Loquat Leaf 300g Menthol 0.34g [0004] For the above four flavors, 45g of Fritillaria sichuanensis liquid extract is taken, crushed into a coarse powder, and soaked for 5 minutes according to the percolation method (Appendix Ⅰ O) under liquid extract and extract. Days later, slowly percolate, collect 38ml of the first decant liquid, store in another device, continue percolation, when the soluble components are completely decanted, the subsequent percolation liquid is concentrated to an appropriate amount, add the primary decant liquid, mix, continue to concen...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8966A61K9/46A61P11/14A61P11/10A61P11/00A61P11/04
Inventor 付立家付建家马筠赵敏姿
Owner BEIJING ASIA EAST BIO PHARMA CO LTD