Preparation method and application of pseudo-ginseng injury tablets
A technology of notoginseng wounds and pills, which is applied in medical formulas, medical preparations containing active ingredients, antineoplastic drugs, etc. It can solve the problems of large dosage, backwardness, and many impurities for patients, and achieve the effect of reducing dosage
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[0015] Example 1
[0016] Take 52.5g of Panax notoginseng, 52.5g of grass black (steamed), 23g of Artemisia serrata, 1.05g of borneol, 492.2g of Drynaria fortunei, 157.5g of safflower, 787.5g of elderberry, and 87.5g of red peony, and add to CO2 supercritical extraction In the vessel, ethanol is used as the entrainer, the entrainer accounts for 4% of the total extraction solvent, the extraction pressure is 15MPa, the temperature is 30°C, and CO 2 The flow rate is 1m1 / g crude drug·min, the extraction time is 150min, and the supercritical extract is obtained. Starch and 70% ethanol are added to make granules, dried and compressed into 500 tablets, each weighing 0.5g.
Example Embodiment
[0017] Example 2
[0018] Take 52.5g of Panax notoginseng, 52.5g of grass black (steamed), 23g of Artemisia serrata, 1.05g of borneol, 492.2g of Drynaria fortunei, 157.5g of safflower, 787.5g of elderberry, 87.5g of red peony, and add to CO 2 In the supercritical extractor, ethanol is used as the entrainer, and the volume percentage of the entrainer in the total extraction solvent is 6%, the extraction pressure is 30MPa, the temperature is 50°C, and CO 2 The flow rate is 3m1 / g crude drug·min, the extraction time is 180min, and the supercritical extract is obtained. Starch and 70% ethanol are added to make granules, dried and compressed into 500 tablets, each weighing 0.5g.
Example Embodiment
[0019] Example 3
[0020] Take 52.5g of Panax notoginseng, 52.5g of grass black (steamed), 23g of Artemisia serrata, 1.05g of borneol, 492.2g of Drynaria fortunei, 157.5g of safflower, 787.5g of elderberry, 87.5g of red peony, and add to CO 2 In the supercritical extractor, ethanol is used as the entrainer. The entrainer accounts for 5% of the total extraction solvent. The extraction pressure is 20MPa, the temperature is 40°C, and CO 2 The flow rate is 2m1 / g crude drug·min, the extraction time is 160min, and the supercritical extract is obtained. Starch and 70% ethanol are added to make granules, dried and pressed into 500 tablets, each weighing 0.5g.
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