Preparation method of alanyl-glutamine freeze-dried powder

Abstract

The invention discloses a preparation method of alanyl-glutamine freeze-dried powder. By improving and regulating the conventional preparation method, adjusting a component adding sequence, controlling temperature more precisely, increasing a refined filtration layer, and the like, finished product quality is more stable, and precision is improved. And moreover, the preparation method further can be adapted to different-scale production, and is wider in scope of application.

Description

technical field

[0001] The invention relates to the field of pharmacy, in particular to a preparation method of alanyl glutamine freeze-dried powder. Background technique

[0002] Alanyl glutamine, molecular formula C 8 h 15 N 3 o 4 , as white or off-white loose lumps. Alanyl glutamine is a component of parenteral nutrition, suitable for patients who need to supplement glutamine, including patients in catabolic and hypermetabolism conditions, alanyl glutamine is usually made into lyophilized powder for preservation At present, in the preparation of alanyl glutamine freeze-dried powder, due to the limitation of the process method, different preparation methods usually have different applicable production scales. Therefore, if the production scale is adjusted, it is often necessary to make certain adjustments to the process. At the same time, due to the inaccurate grasp of some details in the traditional preparation method, there are often errors in the accuracy of the pr...