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Traditional Chinese medicinal composition preparation for preventing and treating senile dementia and preparation method thereof

A technology for senile dementia and traditional Chinese medicine, which is applied in the directions of drug combinations, pharmaceutical formulations, and medical preparations with non-active ingredients, etc., can solve the problems of insignificant curative effect, large side effects, high price, etc. cheap effect

Inactive Publication Date: 2014-04-09
JILIN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, the above drugs are mostly effective at the beginning, and the curative effect is not obvious after long-term use, and the side effects are relatively large, and the price is expensive.

Method used

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  • Traditional Chinese medicinal composition preparation for preventing and treating senile dementia and preparation method thereof
  • Traditional Chinese medicinal composition preparation for preventing and treating senile dementia and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0063] The present invention weighs the medicinal components according to the following weight proportions: 6 ginseng, 10 angelica, 10 polygala, 12 poria, 6 calamus, 6 turmeric and 10 chuanxiong.

[0064] Its preparation process is as follows: (1) add 8 times the amount of water to the decoction pieces of Shichangpu, Angelica, and Chuanxiong medicinal materials and keep it slightly boiled for 8 hours, extract the volatile oil by steam distillation, and use the volatile oil, medicinal residues, Shichangpu, and Angelica aqueous solution for later use; and medicinal dregs in a multi-functional tank, add water and decoct 3 times, the three decoction times are 2, 2 and 1 h respectively, combine the three extracts and the aqueous solutions of Shichangpu, Angelica and Chuanxiong, filter with ultrafiltration membrane, and depressurize the filtrate Concentrate to a clear paste with a relative density of 1.25 (80°C), dry under reduced pressure, and pulverize to obtain extract powder I; (...

Embodiment 2

[0066] The present invention weighs the medicinal components according to the following weight proportions: 10 parts of ginseng, 12 parts of angelica, 15 parts of Polygala, 15 parts of Poria cocos, 10 parts of Shichangpu, 8 parts of curcuma and 10 parts of Chuanxiong.

[0067] The preparation process is as follows: (1) adding 8 times the amount of water to the crude powder of Acorus shichangpu, angelica and chuanxiong, keeping it slightly boiled for 5 hours, extracting the volatile oil by steam distillation, and preparing the volatile oil, dregs and aqueous solutions of shichangpu, angelica and chuanxiong for standby; Put the remaining medicinal materials and medicinal residues in a multifunctional tank, add water and decoct 3 times, the decoction time of the three times is 2, 2, and 1 hour respectively, combine the three extracts and the aqueous solutions of Acorus calamus, Angelica, and Rhizoma Chuanxiong, and filter them with an ultrafiltration membrane. The filtrate is conc...

Embodiment 3

[0069] The present invention weighs the medicinal components according to the following weight ratio: 12 ginseng, 12 angelica, 15 polygala, 14 poria, 8 calamus, 8 turmeric and 10 chuanxiong.

[0070] The preparation process is as follows: (1) adding 8 times the amount of water to the fine powder of Shichangpu and Angelica medicinal materials and keeping it slightly boiled for 8 hours, extracting the volatile oil by steam distillation, and using the volatile oil, medicinal residues, Shichangpu and Angelica aqueous solution for later use; Put the dregs in a multifunctional tank, add water and decoct 3 times, the three decoction times are 2, 2 and 1 h respectively, separate the extracts, combine them, and filter; the filtrate is combined with the above aqueous solution, and concentrated under reduced pressure to a relative density 1.10 (50°C) clear paste, let it cool; take the above concentrate, add ethanol until the alcohol content reaches 60%, let it stand, and filter; the filtr...

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Abstract

The invention discloses a traditional Chinese medicinal composition preparation for preventing and treating senile dementia and a preparation method thereof, and belongs to the technical field of traditional Chinese medicines. The preparation is prepared from ginseng, Chinese angelica, polygala tenuifolia, rhizoma acori graminei, radix curcumae, poria, ligusticum wallichii and other traditional Chinese herbal medicines in a certain ratio, can be mixed with pharmaceutically suitable vectors to prepare various preparations according to a specific process. The invention also provides a preparation of the industrially applicable preparation. The preparation has functions of nourishing yin and tonifying kidney, strengthening spleen and qi, activating blood circulation to remove stasis, and can be used in treatment of senile dementia and syndrome of yin deficiency of spleen and kidney.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and relates to a traditional Chinese medicine combination preparation for preventing and treating senile dementia and a preparation method thereof. Background technique [0002] Senile dementia has a high disability and mortality rate, which seriously affects people's physical and mental health and quality of life. Traditional Chinese medicine does not have the disease name "senile dementia", and senile dementia is scattered in the categories of "vertigo" and "forgetfulness" in traditional Chinese medicine. The name of dementia was first seen in "Jingyue Quanshu", such as "Jingyue Quanshu Volume Thirty-Four Days Collection of Miscellaneous Syndrome Mo Madness and Dementia Treatment" "Dementia syndrome, usually without phlegm, and either stagnation, or failure, or Worrying, doubt, or fear gradually lead to dementia, speech reversal, erratic behavior, or profuse sweating or m...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61K47/48A61P25/28
Inventor 尹建元孟勤杨玉霞于秀华刘继华刘竞研耿聪孙丹丹陈凡波
Owner JILIN UNIV
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