A kind of preparation method of policosanol

Abstract

The invention discloses a preparation method of policosanol. The preparation method comprises the steps of collecting leaves of ripe wheat plant; extracting the leaves through an organic solvent to obtain extract; filtering the extract to remove impurities; then condensing and distilling the extract to obtain crude extract of policosanol; implementing column chromatography on the crude extract of the policosanol; carrying out gas chromatography on policosanol extract subjected to the column chromatography; and carrying out silica gel chromatographic purification to obtain high-purity policosanol. The preparation method, adopting wheat plant which grows in the north in a large area, breaks through geographical limitation of raw material and realizes production and preparation of the policosanol in cold regions in the north, the material is low in cost, easily available and high in content, and content of crude extract can reach 80% at most; meanwhile, the organic solvent in preparing and extracting process can realize regeneration and recycling, which reduces cost and is beneficial to environmental protection and efficient production of policosanol; and the preparation method has strong popularization and application values.

Description

technical field [0001] The invention belongs to the technical field of pharmaceutical preparation, in particular to a preparation method of policosanol. Background technique [0002] Policosanol, also known as sugarcane fatty alcohol, is a lipid-lowering drug for the treatment of hyperlipidemia, which can effectively reduce the cholesterol content in the human body. [0003] At present, policosanol is generally extracted from sugarcane. Since sugarcane mainly grows in the south, it is difficult to extract and prepare it in the cold regions of the north. SUMMARY OF THE INVENTION [0004] The invention provides a preparation method of policosanol, aiming at solving the problem that currently policosanol is generally extracted from sugar cane. Since sugar cane mainly grows in the south, the extraction and preparation of policosanol is difficult to produce in the cold regions of the north. Subject to geographical restrictions. [0005] The object of the present invention is ...

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Problems solved by technology

[0004] The present invention provides a method for preparing policosanol, which aims to solve the problem that policosanol is generally extracted from sugarcane. Since sugarcane mainly grows in the south, the extraction and preparation of policosanol is difficult to produce in cold northern regions. Issues that are geographically restricted

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