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Chitosan antibacterial lotion for gynecology and preparation method thereof

A chitosan, gynecological technology, applied in antibacterial, antifungal, topical antibacterial, etc., can solve the problems of unsafe, low efficiency, easy to produce drug resistance, etc., achieve high antibacterial activity, kill High rate, reducing the effect of tissue exudate

Inactive Publication Date: 2014-05-07
HUNAN HUAYAN BIOTECH DEV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Most of the drugs used for gynecological inflammation on the market today use chemical treatment mechanisms, which often lead to ineffective, unsafe, and drug-resistant consequences. How to find an efficient, safe, and non-resistant substance to prevent, Alleviating and treating gynecological inflammation is an urgent matter

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] A chitosan gynecological antibacterial lotion is a solution prepared by dissolving chitosan in purified water and adjusting the pH to 4.0, and the weight percentage of chitosan in the solution is 0.4%.

[0031] The preparation method comprises the following steps:

[0032] (1) Take 0.4g of chitosan, dissolve in 400g of solvent purified water, start stirring for 30 minutes until the solution is evenly mixed;

[0033] (2) Add 600g of purified water to the stirred solution to make it constant, and adjust the pH to 4.0;

[0034] (3) Use a plate and frame filter to filter the solution after constant volume, and the filter material has a pore size of 0.40um to obtain a semi-finished solution;

[0035] (4) Fill and seal the semi-finished liquid: during the filling process, check the operation of the oral liquid filling machine, start the machine, rinse the pipeline with fresh purified water for more than 10 minutes before use, inhale the semi-finished solution until the pipel...

Embodiment 2

[0040] A chitosan gynecological antibacterial lotion is a solution prepared by dissolving chitosan in purified water and adjusting the pH to 5.2, and the weight percentage of chitosan in the solution is 0.5%.

[0041] The preparation method comprises the following steps:

[0042] (1) Take 0.5g of chitosan, dissolve in 500g of solvent purified water, start stirring for 30 minutes until the solution is evenly mixed;

[0043] (2) Add 500g of purified water to the stirred solution to make it constant, and adjust the pH to 5.2;

[0044] (3) Use a plate and frame filter to filter the solution after constant volume, and the filter material has a pore size of 0.45um to obtain a semi-finished solution;

[0045] (4) Fill and seal the semi-finished liquid: during the filling process, check the operation of the oral liquid filling machine, start the machine, rinse the pipeline with fresh purified water for more than 10 minutes before use, inhale the semi-finished solution until the pipelin...

Embodiment 3

[0050] A chitosan gynecological antibacterial lotion is a solution prepared by dissolving chitosan in purified water and adjusting the pH to 6.5, and the weight percentage of chitosan in the solution is 0.6%.

[0051] The preparation method comprises the following steps:

[0052] (1) Take 0.6g of chitosan, dissolve in 600g of solvent purified water, start stirring for 30 minutes until the solution is evenly mixed;

[0053] (2) Add 400g of purified water to the stirred solution to make it constant, and adjust the pH to 6.5;

[0054] (3) Use a plate and frame filter to filter the solution after constant volume, and the filter material has a pore size of 0.50um to obtain a semi-finished solution;

[0055] (4) Fill and seal the semi-finished liquid: during the filling process, check the operation of the oral liquid filling machine, start the machine, rinse the pipeline with fresh purified water for more than 10 minutes before use, inhale the semi-finished solution until the pipel...

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PUM

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Abstract

The invention discloses a chitosan antibacterial lotion for gynecology, which is a solution prepared through the steps as follows: dissolving chitosan in purified water, and adjusting the pH value to 4.0-6.5, wherein the weight percentage of chitosan in the solution is 0.4-0.6%; the invention further provides a preparation method of the chitosan antibacterial lotion for gynecology. The chitosan antibacterial lotion for gynecology, provided by the invention, is used for treating candida albicans vaginitis, bacterial vaginosis, cervical erosion and other gynecological diseases according to the principles of bacterium resistance and inhibition, and has the effects of inhibiting bacteria, diminishing inflammation, stopping bleeding, relieving pain, ensuring moist wound, reducing percolate of tissues, and promoting healing of the wound.

Description

technical field [0001] The invention relates to a medicine preparation method, in particular to a chitosan gynecological antibacterial lotion and a preparation method thereof. Background technique [0002] At present, gynecological diseases seriously threaten the health of women in our country, showing a trend of younger development. The incidence of gynecological diseases of childbearing age is over 70%; almost 100% of women have suffered from varying degrees of vaginitis, and more than 5% of them have seriously affected their normal work and life due to their illness. More than 400 million women in my country are involved in gynecological medicines. The prevalence rate of gynecological diseases among married women in my country is 46.10%, 48.85% among rural women, and 41.26% among urban women. High prevalence and high recurrence rate are the main features of gynecological inflammatory diseases. Its prevention, mitigation, and treatment are mainly based on drugs, which ha...

Claims

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Application Information

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IPC IPC(8): A61K31/722A61P15/00A61P31/04A61P15/02A61P31/02A61P31/10A61P33/02
Inventor 官建华
Owner HUNAN HUAYAN BIOTECH DEV
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