Application of centipede and pseudo-ginseng extract in preparation of medicine for treating gout and medicine prepared from centipede pseudo-ginseng extract

Abstract

The invention discloses application of centipede and pseudo-ginseng extract in preparation of a medicine for treating gout and a pharmaceutical composition of the centipede pseudo-ginseng extract. The centipede pseudo-ginseng extract contains centipede and pseudo-ginseng total saponin and is prepared by adopting a water decocting method. Pharmacological testing and clinical test prove that the centipede and pseudo-ginseng extract has a good effect for treating gout and has the advantages of high efficiency and low toxicity. The centipede and pseudo-ginseng extract has the effect of reducing serum uric acid level in a rat suffering from hyperuricemia, and the treatment effect is played without adopting the means of inhibiting expression of xanthine oxidase. The centipede and pseudo-ginseng extract has the effect of reducing the serum uric acid level in a mouse suffering from hyperuricemia.

Description

technical field [0001] The present invention relates to the medical use of centipede notoginseng extract and its pharmaceutical composition. Background technique [0002] Gout has become a metabolic disease that seriously threatens human health. Recent studies have found that hyperuricemia is not only the most important biochemical basis of gout, but also closely related to metabolic disorder syndrome. Independent risk factors such as blood pressure and kidney disease have been listed by the United Nations as one of the top 20 chronic diseases in the 21st century. With the increasing incidence of gout worldwide, more and more attention has been paid to the pathogenesis and prevention of hyperuricemia and gout. [0003] Hyperuricemia is the main biochemical marker of gout, and gout is a group of heterogeneous diseases. It is a genetic or acquired tissue damage caused by increased blood uric acid (UA) caused by long-term purine metabolism disorders. metabolic disease. In cl...

AI Technical Summary

Problems solved by technology

Therefore, gout patients also need analgesia while taking long-term drugs that can lower blood uric acid, but there are currently few effective, economical, and safe drugs that can reduce UA and analgesia

my country has a long history of using Chinese herbal medicine to treat gout, but so far there are few Chinese medicine preparations that can effectively reduce blood uric acid clinically.

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