EWOD (electrowetting on dielectric) chip liquid drop driving method and EWOD chip liquid drop driving system

Abstract

The invention provides an EWOD (electrowetting on dielectric) chip liquid drop driving method and an EWOD chip liquid drop driving system. A first capacitor and a second capacitor are relevant to relative positions of liquid drops and driving electrodes, but are irrelevant to driving voltage signal frequency and compositions of the liquid drops, so that the calculated amount in an operation process is required to be reduced greatly. Moreover, by using the EWOD chip liquid drop driving method, whether movement of the liquid drops fails or not can be quickly detected, after the movement of the liquid drops fails, the current stay positions of the liquid drops can be known, namely, when the liquid drops stay on a first driving electrode, a second driving electrode is electrified, so that the liquid drops can overcome obstacles and reach target positions, and follow-up operation of technicians is facilitated.

Description

technical field [0001] The invention relates to the field of biochemical analysis, in particular to an EWOD chip droplet driving method and system. Background technique [0002] In the past two decades, microfluidic technology has made great breakthroughs along with the rapid development of microfabrication technology. new hotspot. The use of digital microfluidic technology to control droplets is to control the power on the drive electrodes of the EWOD chip, and the droplets will move in the direction of the power-on drive electrodes. The array drive electrodes are controlled to be powered on in time sequence, and the droplets will be driven. drive. [0003] Due to defects, dust and other obstacles on the surface of the EWOD chip, the obstacles will hinder the movement of the droplet. If the droplet is interrupted during the movement, the planned path cannot be completed. like figure 1 As shown, the droplets in the array electrode move from the No. 1 driving electrode to...

AI Technical Summary

Problems solved by technology

Since the driving voltage on the driving electrode is set by the peripheral control circuit before the droplet starts to move, the driving voltage is applied to the array electrodes sequentially from No. Move to the No. 4 driving electrode, but when the droplet moves to the No. 3 driving electrode, it stays on the No. 3 driving electrode due to the influence of dust. At this time, it will bring a series of difficulties to control the subsequent movement.

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