Acute renal failure treatment medicine

A technology for acute renal failure and drugs, applied in drug combinations, pharmaceutical formulations, plant raw materials, etc., can solve problems such as poor effect and loss of renal function, and achieve inhibiting inflammatory cell migration, reducing secretion, and inhibiting oxidative stress. Effect

Inactive Publication Date: 2014-12-03
GUANGZHOU NUOSHILIU BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] The main drugs for the treatment of acute renal failure are diuretics, anti-infective drugs and nutritional support drugs. Experimental studies have proved that the oxidative emergency damage that occurs in the process of acute renal failure, if not timely suppressed, can lead to the evolution of acute renal failure to chronic renal failure, and eventually lead to renal failure. Loss of function, currently marketed drugs to suppress inflammation and oxidative stress in acute renal failure are ineffective

Method used

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  • Acute renal failure treatment medicine
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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] A preparation method of a medicine for treating acute renal failure, comprising the following steps:

[0032] a) Preparation of astragalus and angelica mixture: take two traditional Chinese medicines of astragalus and angelica, then add astragalus and angelica with 6 to 8 times the total weight of water, soak for 40 to 100 minutes, heat to boiling for 30 to 40 minutes, and filter to obtain the medicinal solution 1 and medicinal dregs 1, medicinal liquid 1 for later use, add water of 4 to 6 times the total weight of medicinal dregs 1 to medicinal dregs 1, heat to boiling for 30 to 40 minutes, and filter medicinal liquid 2; mix medicinal liquid 1 and medicinal liquid 2. After mixing and concentrating under reduced pressure to powder, the astragalus angelica mixture is obtained;

[0033] b) Preparation of medicine for treating acute renal failure: firstly mix the microcrystalline cellulose, the calcium carbonate and croscarmellose sodium evenly, add the atorvastatin calciu...

Embodiment 2

[0040] Same as Example 1, the difference is:

[0041] In step a, the weight ratio of astragalus and angelica is 1.8:1 to prepare the mixture of astragalus and angelica.

Embodiment 3

[0043] Same as Example 1, the difference is:

[0044] In step a, the weight ratio of astragalus and angelica is 2:1 to prepare the mixture of astragalus and angelica.

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PUM

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Abstract

An acute renal failure treatment medicine comprises atorvastatin calcium, a Radix Astragali and Chinese angelica mixture, and auxiliary materials, and the auxiliary materials comprise microcrystalline cellulose, calcium carbonate, cross-linked sodium carboxymethyl cellulose and magnesium stearate. The acute renal failure treatment medicine provided by the invention can be used for acute renal failure inflammation prevention to inhibit oxidative stress response in order to terminate the development of the acute renal failure to chronic renal failure.

Description

technical field [0001] The invention relates to a medicament, in particular to a medicine for treating acute renal failure. Background technique [0002] The main drugs for the treatment of acute renal failure are diuretics, anti-infective drugs and nutritional support drugs. Experimental studies have proved that the oxidative emergency damage that occurs in the process of acute renal failure, if not timely suppressed, can lead to the evolution of acute renal failure to chronic renal failure, and eventually lead to renal failure. Loss of function, currently marketed drugs for suppressing inflammation and oxidative stress in acute renal failure are ineffective. Contents of the invention [0003] The invention overcomes the deficiencies of the prior art and provides a medicine for treating acute renal failure. The medicine for treating acute renal failure proposed by the invention can inhibit the development of the disease in time and has better effect. [0004] In order to...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/481A61P13/12A61K31/40
Inventor 雷文静
Owner GUANGZHOU NUOSHILIU BIOTECH
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