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A traditional Chinese medicine capsule for treating diabetic retinopathy and its application

A technology for diabetic retina and traditional Chinese medicine capsules is applied in the directions of capsule delivery, medical preparations with inactive ingredients, medical preparations containing active ingredients, etc. The effect of oral dose, guaranteed effective dose, and simple operation process

Active Publication Date: 2016-09-21
BEIJING HANDIAN PHARMA CO LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The above method is only a simple preparation method of traditional Chinese medicine decoction, and does not consider how to fully extract the active ingredients in the medicine, which causes a serious waste of medicinal material resources, but the medicinal effect is not significant; Poor, inconvenient to carry, not suitable for long-term storage

Method used

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  • A traditional Chinese medicine capsule for treating diabetic retinopathy and its application
  • A traditional Chinese medicine capsule for treating diabetic retinopathy and its application
  • A traditional Chinese medicine capsule for treating diabetic retinopathy and its application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0059] Example 1 A kind of traditional Chinese medicine capsule

[0060] API prescription:

[0061] Astragalus 6kg, Ligustrum lucidum 3kg, Motherwort 3kg, Black plum 1.8kg, Coptis 1.2kg, Cinnamon 0.2kg, Budisma 1.2kg

[0062] The concrete steps of described preparation method are as follows:

[0063] (1) Prepare various medicinal materials according to the prescription.

[0064] (2) Add water 10 times the weight of medicinal materials to cinnamon, extract the volatile oil by steam distillation, collect the distilled aqueous solution in another device, and use the dregs for later use; add 2 times the volume of absolute ethanol to dissolve the volatile oil; take 10 times the volume of the volatile oil β-cyclodextrin, an aqueous solution of β-cyclodextrin made by adding water 25 times the weight of β-cyclodextrin; at a speed of 150 rpm, slowly add volatile oil ethanol to the aqueous solution of β-cyclodextrin, After the addition, continue to stir for 1.5 hours, refrigerate f...

Embodiment 2

[0069] Example 2 A kind of traditional Chinese medicine capsule

[0070] API prescription:

[0071] Astragalus 6kg, Ligustrum lucidum 3kg, Motherwort 3kg, Black plum 1.8kg, Coptis 1.2kg, Cinnamon 0.2kg, Budisma 1.2kg

[0072] The concrete steps of described preparation method are as follows:

[0073] (1) Prepare various medicinal materials according to the prescription.

[0074] (2) Take cinnamon, add water 8 times the weight of the medicinal material, extract the volatile oil by steam distillation, collect the distilled aqueous solution in another device, and use the dregs for later use; add 1 volume of absolute ethanol to dissolve the volatile oil, and take 6 times the volume of the volatile oil β-cyclodextrin, β-cyclodextrin aqueous solution made by adding water 15 times the weight of β-cyclodextrin; at a speed of 150 rpm, slowly add volatile oil ethanol solution to the β-cyclodextrin aqueous solution After the addition, continue to stir for 1.5 hours, refrigerate for ...

Embodiment 3

[0079] Example 3 A kind of traditional Chinese medicine capsule

[0080] API prescription:

[0081] Astragalus 6kg, Ligustrum lucidum 3kg, Motherwort 3kg, Black plum 1.8kg, Coptis 1.2kg, Cinnamon 0.2kg, Budisma 1.2kg

[0082] The concrete steps of described preparation method are as follows:

[0083] (1) Prepare various medicinal materials according to the prescription.

[0084] (2) Take cinnamon, add water 12 times the weight of the medicinal material, extract the volatile oil by steam distillation, collect the distilled aqueous solution in another device, and use the dregs for later use; add 3 times the volume of absolute ethanol to dissolve the volatile oil, and take 20 times the volume of the volatile oil β-cyclodextrin, β-cyclodextrin aqueous solution made by adding water 40 times the weight of β-cyclodextrin; at a speed of 150 rpm, slowly add volatile oil ethanol solution to the β-cyclodextrin aqueous solution After the addition, continue to stir for 1.5 hours, refrig...

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Abstract

The invention provides a traditional Chinese medicine capsule for treating diabetic retinopathy and an application of the traditional Chinese medicine capsule for treating diabetic retinopathy. The traditional Chinese medicine comprises the following raw materials in parts by weight: 30 to 60 parts of astragalus membranaceus, 9 to 15 parts of glossy privet fruit, 9 to 30 parts of leonurus, 3 to 10 parts of smoked plum, 2 to 9 parts of coptis chinensis, 1 to 5 parts of cortex cinnamomi and 3 to 9 parts of butterflybush flower. The preparation method of the capsule comprises the following steps: extracting a volatile oil from the cortex cinnamomi and enveloping the volatile oil with Beta-cyclodextrin; extracting medicinal residues of the cortex cinnamomi and the rest of medicinal materials by virtue of an ethanol solution with the volume percentage concentration of 30% to 80%; refining an extract with macroporous adsorption resin and drying so as to obtain dry extract powder; adding a volatile oil clathrate into the dry extract powder, evenly mixing, adding pharmaceutically acceptable auxiliary materials and filling into a capsule so as to obtain the traditional Chinese medicine capsule. Compared with the prior art, the content of active substances in the traditional Chinese medicine capsule provided by the invention is obviously improved, so that the obvious pharmacologic action of the traditional Chinese medicine capsule provided by the invention is achieved.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and in particular relates to a traditional Chinese medicine capsule for diabetic retinopathy and its application. Background technique [0002] Diabetic Retinopathy (DR) is one of the serious and common eye complications of diabetes. With the prolongation of the duration of diabetes, the incidence of DR also increased. The incidence of diabetic retinopathy is about 50% in those with a course of more than 8 years. The early symptoms of the disease are not obvious and are easy to be ignored. In the late stage, there is no effective control method, and the disease is lingering and intractable. If the disease is not treated, the consequences are serious, and it is the main cause of adult blindness, with a blinding rate of 8-12%, which has a serious adverse effect on the quality of life of the affected population. Therefore, the prevention and treatment of DR has become a major research ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/736A61K9/48A61K47/48A61P3/10A61P9/10
Inventor 林德良
Owner BEIJING HANDIAN PHARMA CO LTD
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