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Lotus plumule chloroform extract and preparation method and use thereof

An extract, lotus seed heart technology, applied in the field of lotus seed heart chloroform extract, to achieve the effect of relieving airway obstruction and effective tracheal smooth muscle relaxation

Inactive Publication Date: 2015-01-28
SOUTH CENTRAL UNIVERSITY FOR NATIONALITIES
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

At present, there are no relevant reports at home and abroad on the use of lotus seed heart chloroform extract to relax airway smooth muscle in the treatment of asthma.

Method used

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  • Lotus plumule chloroform extract and preparation method and use thereof
  • Lotus plumule chloroform extract and preparation method and use thereof

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Embodiment Construction

[0022] The present invention will be described in detail below in conjunction with the examples, but the protection scope of the present invention is not limited to the following examples.

[0023] 1, the preparation of lotus seed heart chloroform extract:

[0024] The lotus seed heart comes from Honghu, Hubei. The dried lotus seed heart is selected as a raw material and ground into powder; the ethanol with a volume concentration of 95% is heated and refluxed three times to collect the extract; the extract is centrifuged to collect the upper layer, and then the upper layer is evaporated to dryness with a rotary evaporator, Collect the residue; dissolve the residue in hydrochloric acid solution with a mass concentration of 2%, extract 3 times with petroleum ether, remove grease, and collect the filtrate; adjust the pH value of the filtrate to 10 with ammonia water, and then use chloroform to Extraction, collecting the extract and evaporating to dryness to obtain the extract, t...

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Abstract

The invention provides a lotus plumule chloroform extract. The lotus plumule chloroform extract is prepared by adopting the following steps: selecting dry lotus plumule as a raw material, and grinding into powder; adopting methyl alcohol or ethyl alcohol to carry out heating reflux extraction two to four times, and collecting an extract; carrying out centrifugal treatment on the extract, collecting supernatant, then evaporating the supernatant to dryness by using a rotary evaporator, and collecting residues; dissolving the residues to a hydrochloric acid solution, extracting two to four times by using petroleum ether, removing oils and fats, and collecting a filtrate; adjusting the pH value of the filtrate to be 9-11, then extracting by using chloroform, collecting an extract liquor and evaporating to obtain an extract, namely the lotus plumule chloroform extract. Experiments show that the extract can relax airway smooth muscle, and can be used for relieving the airway obstruction of an asthma patient, so that the lotus plumule chloroform extract can be applied to the preparation of medicine for treating bronchial asthma.

Description

technical field [0001] The invention provides a lotus seed heart chloroform extract, which is used for preparing medicines for preventing or treating bronchial asthma, and belongs to the technical field of traditional Chinese medicine. Background technique [0002] Bronchial asthma (hereinafter referred to as "asthma") is a common multiple chronic respiratory disease, and its pathogenesis is not yet fully understood. At present, there are at least 300 million people in the world, and there are nearly 30 million asthma patients in my country. Asthma has become the second leading cause of death and disability in the world after cancer. According to the latest survey released at the press conference of "my country's Asthma Disease Incidence, Treatment Progress and Asthma Management Ten-Year Progress News Bulletin", from 1990 to 2000, the incidence of asthma in mainland China increased from 0.91% to 1.97%. (more than doubled). The survey data of the three cities of Beijing, Cho...

Claims

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Application Information

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IPC IPC(8): A61K36/62A61P11/06
CPCA61K36/62A61K2236/333A61K2236/39A61K2236/51
Inventor 刘庆华陈微微谈丽
Owner SOUTH CENTRAL UNIVERSITY FOR NATIONALITIES
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