Method for filtering medicinal fluid impurities

A fluid and impurity technology, applied in the field of filtering impurities in medicinal fluids, can solve problems such as loss of functional groups

Inactive Publication Date: 2015-01-28
华文蔚
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The combination of heat and fluids can lead to degradation of alkaline membranes and loss of functional groups due to subsequent leakage of contaminants from the membrane

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] A method of filtering impurities in a pharmaceutical fluid comprising passing the drug through a porous membrane comprising a plurality of exchange resins, the exchange resin being a porous ion exchange resin capable of removing materials of different sign charges from the fluid prior to administering the drug , the size of the resin particles after pulverization is 12 microns, and the median particle size is about 40 microns. The film provides a fluid containing less than 500 ppb of charged impurities at a temperature of 90 ° C, at a flow rate of 7000-9000 cm3min-1 In the water, the amount of anion or cationic impurities in the treated fluid is less than 5ppbv / v. The polymeric material of the porous membrane includes a mixture of polypropylene and polyethylene, and the structure is melt-casting into a cast membrane.

Embodiment 2

[0021] A method of filtering impurities in a pharmaceutical fluid comprising passing the drug through a porous membrane comprising a plurality of exchange resins, the exchange resin being a porous ion exchange resin capable of removing materials of different sign charges from the fluid prior to administering the drug , the size of the resin particles after pulverization is 50 microns, and the median particle size is about 40 microns. The film provides a fluid containing less than 500 ppb of charged impurities at a temperature of 90 ° C, at a flow rate of 7000-9000 cm3min-1 In the water, the amount of anion or cationic impurities in the treated fluid is less than 5ppbv / v. The polymeric material of the porous membrane includes a mixture of polypropylene and polyethylene, and the structure is melt-casting into a cast membrane.

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Abstract

The invention discloses a method for filtering medicinal fluid impurities. The method comprises the following steps: enabling the medicine to pass through a porous membrane comprising various exchange resins before medicine is used, wherein the exchange resins are porous ion exchange resins capable of removing materials with charges of different signs in a fluid, and the sizes of resin particles after being smashed is 12-50 microns, and the median particle diameters of the resin particles are about 40 microns; when the membrane is at the temperature of 90 DEG C, the fluid with charged impurities of smaller than 500 ppb is provided, in water with a flow rate of 7000-9000 cm<3> / min, the amount of anionic or cationic impurities of the treated fluid is smaller than 5 ppbv / v, the polymeric material of the porous membrane comprises the mixture of polypropylene and polyethylene, and the porous membrane is a fusion casting forming membrane structurally. The method is good in filter effect and high in speed.

Description

technical field [0001] The invention relates to a method for filtering impurities in medicinal fluid. Background technique [0002] In the process of sewage purification, filtration and decomposition of biological organic matter are carried out, sometimes harmful gas is discharged from sewage or gas is injected into liquid, and in addition, sewage sludge is dehydrated (dried). The filtering structure of the present invention can be effectively applied to the above-mentioned technological process. In some cases, a liquid containing solids is passed through a filter structure to filter out the solids; in other cases, gas is injected into the liquid through the structure in the form of microscopic bubbles during dispersion. [0003] Various methods are known for filtration (of sewage) and sludge dewatering, such as sand filtration, fixed plate filtration, glued pebble filtration, fabric or wire mesh filtration and mechanical filtration (centrifugal and vacuum filtration, sludg...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C02F9/04
CPCC02F1/42C02F1/44
Inventor 华文蔚
Owner 华文蔚
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