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Drug for treating end-stage liver diseases caused by chronic hepatitis B and preparation method of drug

A technology for chronic hepatitis B and liver disease, applied in the field of medicine, can solve the problems of low cure rate and poor effect, and achieve remarkable curative effect

Inactive Publication Date: 2015-03-04
THE SECOND HOSPITAL OF NANJING
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, conventional medical comprehensive treatment is given for chronic hepatitis B end-stage liver disease, including general supportive treatment, conventional liver protection preparations, transfusion of human albumin and plasma, etc. Glycoside analogues are antiviral; these treatments are less effective and have a lower cure rate

Method used

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  • Drug for treating end-stage liver diseases caused by chronic hepatitis B and preparation method of drug

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0045] A medicine for treating chronic hepatitis B end-stage liver disease, which is composed of the following raw materials proportioned by weight: 30 parts of astragalus, 20 parts of heterophylla, 20 parts of fried Atractylodes macrocephala, 10 parts of tangerine peel, 10 parts of angelica, 10 parts of poria cocos, Zhigancao 3 parts, Scutellaria baicalensis 10 parts, Chuanxiong 10 parts.

[0046] The amount of the above-mentioned raw materials used can be increased or decreased within the above-mentioned range according to the specific conditions of the patients.

[0047] For heavy wet:

[0048] It also includes the following raw materials in proportion by weight: 30 parts of capillary, 5 parts of cooked rhubarb, and 10 parts of knotweed.

[0049] For the heat-heavy:

[0050] It also includes the following raw material composition according to the weight ratio: 20 parts of Desmodium, 20 parts of Radix Paeoniae Rubra, and 10 parts of Gardenia.

[0051] For those with heavy...

Embodiment 2

[0055]A medicine for treating chronic hepatitis B end-stage liver disease, which is composed of the following raw materials proportioned by weight: 60 parts of astragalus, 30 parts of heterophylla, 30 parts of fried Atractylodes macrocephala, 15 parts of tangerine peel, 20 parts of angelica, 15 parts of poria cocos, 6 parts of roasted licorice, 20 parts of skullcap, and 20 parts of Chuanxiong.

[0056] The amount of the above-mentioned raw materials used can be increased or decreased within the above-mentioned range according to the specific conditions of the patients.

[0057] For heavy wet:

[0058] It also includes the following raw materials in proportion by weight: 60 parts of capillary, 20 parts of cooked rhubarb, and 20 parts of knotweed.

[0059] For the heat-heavy:

[0060] It also includes the following raw material composition according to the weight ratio: 30 parts of Desmodium, 30 parts of Radix Paeoniae Rubra, and 20 parts of Gardenia.

[0061] For those with ...

Embodiment 3

[0064] Embodiment three: (preferred embodiment)

[0065] A medicine for treating chronic hepatitis B end-stage liver disease, which is composed of the following raw materials proportioned by weight: 40 parts of astragalus, 25 parts of heterophylla, 25 parts of fried Atractylodes macrocephala, 12 parts of tangerine peel, 15 parts of angelica, 12 parts of poria cocos, Zhigancao 4 parts, Scutellaria baicalensis 15 parts, Chuanxiong 15 parts.

[0066] The amount of the above-mentioned raw materials used can be increased or decreased within the above-mentioned range according to the specific conditions of the patients.

[0067] For heavy wet:

[0068] It also includes the following raw materials in proportion by weight: 40 parts of capillary, 10 parts of cooked rhubarb, and 15 parts of knotweed.

[0069] For the heat-heavy:

[0070] It also includes the following raw material composition according to the weight ratio: 25 parts of Desmodium, 25 parts of Radix Paeoniae Rubra, an...

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Abstract

The invention discloses a drug for treating end-stage liver diseases caused by chronic hepatitis B. The drug is prepared from the following raw materials in parts by weight: 30-60 parts of astragalus, 20-30 parts of radix pseudostellariae, 20-30 parts of fried rhizoma atractylodis macrocephalae, 10-15 parts of tangerine peel, 10-20 parts of angelica sinensis, 10-15 parts of tuckahoe, 3-6 parts of honey-fried licorice roots, 10-20 parts of scutellaria baicalensis and 10-20 parts of ligusticum wallichii. The traditional Chinese medicine composition is prepared by using a conventional traditional Chinese medicine preparation method and comprises the dosage forms such as a decoction, a capsule or powder. The drug for effectively treating end-stage liver diseases including chronic and acute liver failure, chronic liver failure and decompensated cirrhosis caused by chronic hepatitis B is created on the basis of multi-year clinical experience and is remarkable in curative effect.

Description

technical field [0001] The invention belongs to the field of medicine, in particular to a medicine for treating chronic hepatitis B end-stage liver disease. Background technique [0002] "Ming Zhi Zhi Zhang" says "the disease of jaundice mostly arises from diet and fatigue". "Three Causes, Extremes and One Disease Syndrome Prescriptions" says that "if it occurs in the kidney, it is black jaundice. If we look at the cause, it is wind, cold, heat and dampness on the outside, joy, anger and shock on the inside, and fatigue from drinking, eating and drinking". Professor Qian Ying believes that the etiology and pathogenesis of chronic liver failure are very complex, mainly as "exuberance of heat and toxin in the liver and gallbladder, or accumulation of dampness and toxin, stagnation of toxin and blood stasis, damage to both liver and liver, spleen and kidney qi and yin or yin and yang damage". Hu Jianhua et al. prospectively investigated the symptoms and signs of 260 patients w...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/752A61P1/16
CPCA61K36/481A61K36/076A61K36/185A61K36/232A61K36/236A61K36/28A61K36/284A61K36/36A61K36/484A61K36/53A61K36/539A61K36/65A61K36/704A61K36/708A61K36/71A61K36/744A61K36/752A61K2236/15A61K2236/331A61K2300/00
Inventor 谭善忠肖倩沈建军孙薇薇蒋淑莲梁重锋俞曦汪增秀
Owner THE SECOND HOSPITAL OF NANJING
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