Magnetic resonance image based cerebral micro-bleeding computer auxiliary detection system

A magnetic resonance image, computer-aided technology, applied in the directions of diagnostic recording/measurement, medical science, diagnosis, etc., can solve the problem of not considering the prior distribution probability density position information of cerebral microbleeds, and the multi-dimensional image features of cerebral microbleeds need to be further explored. , The complementary relationship between different sequences of image information is not fully considered, so as to shorten the time spent, the detection results are credible, and the detection results are more effective.

Inactive Publication Date: 2015-03-18
PEKING UNIV
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Problems solved by technology

[0013] However, the currently known computer-aided detection methods for cerebral microbleeds do not fully consider the information complementarity between different sequence images, and the multi-dimensional image features of cerebral microbleeds need to be further explored.
In addition, all known computer-aided detection methods do not consider

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  • Magnetic resonance image based cerebral micro-bleeding computer auxiliary detection system
  • Magnetic resonance image based cerebral micro-bleeding computer auxiliary detection system
  • Magnetic resonance image based cerebral micro-bleeding computer auxiliary detection system

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Embodiment Construction

[0042] The present invention will be described in detail below in conjunction with the accompanying drawings and embodiments. The present invention comprises five main modules altogether, as figure 1 No, the specific introduction is as follows:

[0043] 1. Image import module: Import T1, T2 and GRE T2* brain magnetic resonance images from the same patient into the computer-aided detection system for cerebral microbleeds.

[0044] 2. Image preprocessing module:

[0045] 1) Scale the image uniformly to a size of 512×512 pixels;

[0046] 2) Image position registration;

[0047] 3) if figure 2 As shown, with the help of T1 and T2 images, the regions corresponding to the skull, ventricle, cerebrospinal fluid, and meninges that are unlikely to have cerebral microhemorrhages in the GRE T2* image were removed, including the following details:

[0048] ①Use the global threshold segmentation algorithm to remove the skull and obvious cerebrospinal fluid areas in the original T1 ima...

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Abstract

The invention provides a magnetic resonance image based cerebral micro-bleeding computer auxiliary detection system and belongs to the medical image computer auxiliary detection field. The magnetic resonance image based cerebral micro-bleeding computer auxiliary detection system comprises five portions of an image import module, an image preprocessing module, a characteristic extraction module, an automatic detection module and a cerebral micro-bleeding automatic detection report output module. According to the magnetic resonance image based cerebral micro-bleeding computer auxiliary detection system, the characteristics of T1, T2 and GRET2* images are comprehensively considered, the prior information of the cerebral micro-bleeding of different cerebral positions is obtained through a cerebral micro-bleeding focus prior distribution probability template, and a random forest classifier is combined to perform the automatic detection on the cerebral micro-bleeding focus; the system sensitivity is 0.890 and every case comprises 1.530 false positive focuses in average through a test; the magnetic resonance image based cerebral micro-bleeding computer auxiliary detection system is objective and high in repeatability in comparison with the traditional manual discriminant method and the magnetic resonance image based cerebral micro-bleeding computer auxiliary detection system is accurate and reliable in comparison with the existing computer auxiliary detection method; the operation is simple and convenient, the identification result of the cerebral micro-bleeding focus can be objectively provided, and meanwhile the abundant information is provided for the reference of doctors.

Description

technical field [0001] The invention belongs to the field of computer-aided detection of medical images, and specifically relates to a brain detection system based on texture features of regions of interest in magnetic resonance images (brain parenchyma regions in images), prior distribution probability templates of cerebral microbleeds, and random forest classifiers. Microbleed computer-aided detection system. Background technique [0002] Cerebral microhemorrhage is a kind of subclinical damage of brain parenchyma caused by microvascular disease in the brain and characterized by microhemorrhage. In recent years, the improved detection rate of cerebral microbleeds by new magnetic resonance imaging sequences has further deepened our understanding of cerebral microbleeds. Cerebral microbleeds are common in patients with ischemic stroke or intracranial hemorrhage, and are also common in the elderly. How their appearance affects the prognosis of the disease, and whether their...

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Application Information

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IPC IPC(8): A61B5/055
CPCA61B5/055
Inventor 李彦黄一宁张珏方竞
Owner PEKING UNIV
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