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Application of phellinus igniarius serving as drug in treatment of tumors

A tumor drug, the technology of Phellinus Phellinus, applied in the direction of anti-tumor drugs, drug combinations, medical raw materials derived from fungi, etc., to achieve important economic and social benefits

Active Publication Date: 2015-04-08
安徽省森湶谷药业股份有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although there are new anti-tumor drugs coming out every year in the world, human beings still do not have an effective method to defeat cancer. The need for anticancer drugs is particularly urgent

Method used

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  • Application of phellinus igniarius serving as drug in treatment of tumors
  • Application of phellinus igniarius serving as drug in treatment of tumors
  • Application of phellinus igniarius serving as drug in treatment of tumors

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0334] Embodiment 1: Phellinus granule preparation

[0335] Take Phellinus 2000g, prepare according to the following method:

[0336] (a) Add 15 times the amount of water for the first time, decoct for 2 hours, add 12 times the amount of water for the second time, decoct for 2 hours, combine the medicinal liquid, filter the medicinal liquid, take the filtrate, concentrate to a relative density of 1.10-1.15 (60 ℃), add 95% ethanol to make the alcohol content reach 80%, precipitate, let it stand for 24 hours, filter to obtain a precipitate, and recover the ethanol from the filtrate to obtain a water extract;

[0337] (b) the water extract is concentrated, dried, and pulverized to obtain a dry cream powder;

[0338] (c) the precipitate is dried and pulverized to obtain a precipitated powder;

[0339] (d) Fully mix the obtained dry paste powder and precipitated powder with an appropriate amount of dextrin, granulate with ethanol as a binder, and dry to make granules.

Embodiment 2

[0340] Embodiment 2: Phellinus granule preparation

[0341] Take Phellinus 3000g, prepare according to the following method:

[0342] (a) Add 15 times the amount of 95% ethanol to reflux and extract twice, the first time is 3 hours, and the second time is 2 hours. Combine the medicinal liquids, filter the medicinal liquids, recover ethanol, and obtain an alcohol extract;

[0343] (b) Add water to decoct the medicinal dregs after alcohol extraction twice, add 15 times the amount of water for the first time, decoct for 2 hours, add 12 times the amount of water for the second time, decoct for 2 hours, combine the medicinal liquid, and filter the medicinal liquid , take the filtrate, concentrate until the relative density is 1.10-1.15 (60°C), add 95% ethanol to make the alcohol content reach 80%, precipitate, let stand for 24 hours, absorb the supernatant, reclaim the ethanol, and obtain the water extract;

[0344] (c) the resulting alcohol extract and water extract are combined...

Embodiment 3

[0346] Embodiment 3: Phellinus Phellinus tablet preparation

[0347] Take Phellinus 25000g, prepare according to the following method:

[0348] (a) Add 15 times the amount of water for the first time, decoct for 2 hours, add 12 times the amount of water for the second time, decoct for 2 hours, combine the medicinal liquid, filter the medicinal liquid, take the filtrate, concentrate to a relative density of 1.10-1.15 (60 ℃), add 95% ethanol to make the alcohol content reach 70%, precipitate, let it stand for 24 hours, absorb the supernatant, reclaim the ethanol, and obtain the water extract;

[0349] (b) concentrating, drying, and pulverizing to obtain dry cream powder;

[0350] (c) the precipitate is dried and pulverized to obtain a precipitated powder;

[0351] (d) Fully mix the obtained dry cream powder and precipitated powder with an appropriate amount of sucrose, granulate with ethanol liquid as a binder, dry, add an appropriate amount of magnesium stearate, mix evenly, ...

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Abstract

The invention discloses an application of phellinus igniarius serving as a drug in treatment of tumors. The prepared drug has a good curative effect on such tumors as liver cancer, lung cancer, bladder cancer, colon cancer, cervical cancer, breast cancer, leukemia, lymphoma, osteosarcoma, prostate cancer and gastrointestinal stromal tumor, and not only provides theoretical foundation for the application of the phellinus igniarius in preparation of antitumor drugs and the clinical application thereof, but also has important significance on the comprehensive utilization and industrial development of phellinus igniarius resources, and has important economic benefits and social benefits.

Description

technical field [0001] The invention relates to the application of Phellinus Phellinus as a medicine for treating tumors, and belongs to the technical field of medicines. Background technique [0002] Tumor is a kind of common and frequently-occurring disease. It is a new organism formed by the abnormal growth and differentiation of clonal abnormal proliferation and differentiation due to gene mutation and loss of normal regulation of its growth and differentiation under the long-term action of various internal and external tumorigenic factors. or vegetation. Tumors are divided into benign tumors and malignant tumors, and malignant tumors are subdivided into three types: carcinoma derived from epithelial tissue, sarcoma derived from mesenchymal tissue, and carcinosarcoma. Usually people say "cancer" refers to all malignant tumors. [0003] Malignant tumor is one of the most important malignant diseases that threaten human health, and it is the first cause of death of the g...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/07A61P35/00A61P35/02
CPCA61K9/1652A61K9/2018A61K9/485A61K36/07
Inventor 李宁王开金余春富尹维龙陈刚
Owner 安徽省森湶谷药业股份有限公司
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