Traditional Chinese medicine composition for removing chloasma, and preparation method and application thereof

A technology for removing chloasma and a composition, which is applied in the field of traditional Chinese medicine compositions that can effectively remove chloasma, can solve the problems of significant side effects, obvious side effects, and high cost, and achieve the effect of significant freckle removal, simple preparation, and severe rebound

Inactive Publication Date: 2015-04-29
HUNAN YANDI BIOLOGICAL ENG
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the above-mentioned composition has a certain freckle-removing effect, its components are complicated, its side effects are obvious, and its cost is high. It needs to be used simultaneously with internal medicine and external medicine, and its generalizability is not strong.
[0006] In addition, other freckle-dispelling traditional Chinese medicine compositions currently disclosed have poor comprehensive treatment effects for freckle-removal, and have significant side effects.

Method used

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  • Traditional Chinese medicine composition for removing chloasma, and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] The preparation of embodiment 1 grape seed extract

[0037] Crush grape seeds into coarse powder, reflux extraction with 60% ethanol for 2 times, each time for 1 hour, solvent ratio 1:40, to obtain grape seed proanthocyanidin extract, and use spray drying to retain the activity of active ingredient proanthocyanidin.

Embodiment 2

[0039] 1. Composition of raw materials: 5g of Salvia miltiorrhiza, 3g of safflower, 4g of angelica, 3g of rose, 3g of Angelica dahurica, 0.2g of grape seed extract (prepared in Example 1), 7g of maltodextrin.

[0040] 2. Preparation steps:

[0041] (1) Take salvia miltiorrhiza, safflower, angelica, rose flower, and angelica dahurica according to the dosage, mix them after crushing, add 248ml of water, soak for 30 minutes, decoct for 120 minutes, filter under reduced pressure, filtrate for later use, and keep the medicinal residues;

[0042] (2) Add 186ml of water to the dregs obtained in step (1), decoct for 60min, filter under reduced pressure, and the filtrate is for subsequent use;

[0043] (3) Combine the filtrate obtained in step (1) and step (2), pass through a 200-mesh sieve and a 400-mesh sieve in turn, concentrate the filtrate to a relative density of 1.2, add grape seed extract, add maltodextrin, and spray dry to obtain a powder. The powdered traditional Chinese medic...

Embodiment 3

[0045] 1. Salvia 5g, safflower 3g, angelica 4g, rose 3g, angelica dahurica 3g, grape seed extract 0.2g, maltodextrin 7g.

[0046] 2. Preparation steps:

[0047] Compared with Example 1, the only difference is that the amount of water added in step (1) is 150ml, and the amount of water added in step (2) is 120ml.

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Abstract

The invention relates to a traditional Chinese medicine composition for removing chloasma. The composition is prepared from the following raw materials in parts by weight: 2 to 8 parts of radix salviae miltiorrhizae, 1 to 6 parts of safflowers, 2 to 7 parts of Chinese angelica, 1 to 6 parts of rose flowers, 1 to 6 parts of radix angelicae, 0.1 to 0.5 part of a grape seed extract, and 0-10 parts of maltodextrin. The traditional Chinese medicine composition provided by the invention plays an effect of promoting blood circulation to remove blood stasis and removing chloasma, and is mainly used for treating qi-blood disharmony and facial chloasma caused by face stasis.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and in particular relates to a traditional Chinese medicine composition capable of effectively removing chloasma, a preparation method and an application. Background technique [0002] Chloasma is commonly known as "butterfly spots", "liver spots" or "pregnancy spots". It mainly occurs on the face, mainly on the cheeks, cheeks, nose, forehead, and chin. It is brown or black patches with unclear boundaries, and most of them are symmetrical. The appearance of chloasma is mostly related to endocrine, especially related to estrogen level in women. Chloasma may appear in irregular menstruation, pregnancy, taking contraceptive pills, poor liver function and chronic kidney disease. In addition, sun exposure and mental factors will also aggravate the disease. [0003] Traditional Chinese medicine believes that the occurrence of chloasma is mostly due to insufficient kidney yin, the failure o...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/87A61P17/00
Inventor 王玉兰赵立彬黄凤飞董明王春芳郭建文盛继宗
Owner HUNAN YANDI BIOLOGICAL ENG
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