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Traditional Chinese medicine for treating polymyalgia rheumatica and applications of traditional Chinese medicine

A technology of polymyalgia rheumatica and traditional Chinese medicine, applied in the field of traditional Chinese medicine, can solve problems such as large side effects, complicated treatment process, and pain of patients, and achieve quick results

Inactive Publication Date: 2015-04-29
崔合芳
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Most of the prior art uses western medicine for treatment, but the treatment process is complicated and the side effects are large, which brings pain and inconvenience to the patients

Method used

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  • Traditional Chinese medicine for treating polymyalgia rheumatica and applications of traditional Chinese medicine
  • Traditional Chinese medicine for treating polymyalgia rheumatica and applications of traditional Chinese medicine

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Embodiment 1, the preparation of Chinese medicine oral liquid of the present invention

[0027] In order to provide medicines for acute and chronic toxicity tests and clinical trials, and to verify the preparation process of the present invention, the traditional Chinese medicine oral liquid is produced according to the traditional Chinese medicine formula of the present invention. Ratio, B is the minimum range ratio of the formula, and C is the maximum range ratio of the formula. The quantities of Chinese herbal medicines in each proportion are shown in Table 1.

[0028] Table 1 Quantity table of Chinese herbal medicines in each proportion (unit: kg)

[0029]

[0030] The above-mentioned Chinese medicine prescription can be made into Chinese medicine oral liquid through the following steps:

[0031] (1) Accurately weigh according to the traditional Chinese medicine prescription of the present invention: Chuangui, Xiawu, Banfenghe, Jinshen, Huangmao Rong, Dianqiang...

Embodiment 2

[0034] Embodiment 2, the animal toxicity test of Chinese medicine oral liquid of the present invention

[0035] Preliminary experiments show that the oral liquid of the present invention has very little toxicity and cannot detect LD 50 , therefore, feed according to the maximum consumption.

[0036] 1. Animal acute toxicity test

[0037] Medicine: Chinese medicine oral liquid A, B, C obtained in Example 1 of the present invention.

[0038] Experimental animals: normal grade NIH mice, weighing 21g±2g, half male and half male, and all female rats are sterile.

[0039] Method and Results:

[0040] 1) The experimental mice were randomly divided into 4 groups of male and female, 3 groups were given three kinds of oral liquid of traditional Chinese medicine, the volume was 2ml / 10g body weight, and the remaining group was the control group, which was given the same volume of normal saline, closely Observe for 8 hours and make records, and continue to observe for 7 days;

[0041]...

Embodiment 3

[0050] Embodiment 3, clinical trial

[0051] (1) Subject information

[0052] From August 2011 to August 2014, 240 patients with polymyalgia rheumatica who were admitted for clinical trials were selected, including 152 females and 88 males, aged 51-69, who were selected as subjects Symptoms include varying degrees of symmetrical neck, shoulder girdle, or proximal pelvic girdle muscle pain, stiffness, discomfort, or unilateral or limited muscle group symptoms, and have been diagnosed with polymyalgia rheumatica by the hospital.

[0053] (2) Grouping

[0054] The subjects were divided into three groups on average, 80 cases in each group, the course of disease and average age were similar, and they were numbered as groups A, B and C respectively.

[0055] (3) Test drugs: A, B, and C traditional Chinese medicine oral liquids prepared in Example 1.

[0056] (4) Test method

[0057] A, B, and C three groups of patients were respectively orally administered the A, B, and C tradit...

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Abstract

The invention discloses a traditional Chinese medicine for treating polymyalgia rheumatica and application of the traditional Chinese medicine, belonging to the technical field of traditional Chinese medicines. The traditional Chinese medicine is prepared from the following traditional Chinese medicinal materials: cinnamomum wilsonii gamble, rhizoma corydalis decumbentis, semiliquidambar cathayensis, gentiana sarcorrhiza ling et ma, ficus fulva reinw., denseflower bulbophyllum herb, bulbophvl-lum calodictyon schltr, semen sinapis albae, and gaultheria pyroloides. According to the traditional Chinese medicine, the monarch and subjects of the formula are combined and are complementary with each other, and the traditional Chinese medicine has the efficacies of warming channels and expelling cold, activating meridians to stop pain, dispelling the wind and removing dampness, invigorating spleen and supplementing qi, and tonifying the kidney and moistening the lung, and has the significant effects of fast taking effect and treating the symptoms and the causes when used for treating polymyalgia rheumatica. Compared with the traditional Chinese medicine composition in the prior art, the traditional Chinese medicine has the marked technical advantages of fast taking effect, treating the symptoms and the causes and the like, and is convenient and easy, free from any toxic or side effects.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine for treating polymyalgia rheumatica. Background technique [0002] Polymyalgia rheumatica (PMR) is a clinical syndrome characterized by pain in the extremities and proximal trunk. It generally includes the following three main points: onset at the age of 50 or above; pain and morning stiffness in 2 of the 3 susceptible parts of the shoulder girdle, pelvic girdle, and neck, lasting for more than 30 minutes and lasting for more than 1 month; plus Evidence of systemic reactions such as elevated erythrocyte sedimentation rate over 40 mm / h or 50 mm / h. The onset of PMR is insidious, with systemic symptoms such as low fever, fatigue, fatigue, and weight loss. The typical clinical manifestations are symmetrical neck, shoulder girdle or proximal pelvic girdle muscle pain, stiffness and discomfort. It can also be unilateral or limited ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/898A61P29/00
CPCA61K9/0095A61K36/185A61K36/237A61K36/31A61K36/45A61K36/515A61K36/54A61K36/60A61K36/66A61K36/898A61K2236/331A61K2236/39A61K2236/51A61K2300/00
Inventor 崔合芳
Owner 崔合芳
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