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A traditional Chinese medicine composition for removing chloasma and its application and preparation method

A composition and technology of chloasma, applied in the direction of drug combination, medical preparations containing active ingredients, pharmaceutical formulas, etc., can solve problems such as inability to treat chloasma and aggravation of chloasma

Active Publication Date: 2018-03-23
JIANGSU KANION PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Unreasonable formula not only cannot achieve the effect of treating chloasma, but may lead to the aggravation of chloasma

Method used

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  • A traditional Chinese medicine composition for removing chloasma and its application and preparation method
  • A traditional Chinese medicine composition for removing chloasma and its application and preparation method
  • A traditional Chinese medicine composition for removing chloasma and its application and preparation method

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0071] The preparation of embodiment 1 Chinese medicine composition

[0072] Wash 60g of Angelica sinensis, 30g of Eclipta chinensis, 30g of Ligustrum lucidum, and 40g of roses, add 1280g of drinking water, heat to 80°C, decoct in water three times, each decocting for 120 minutes, to obtain the filtrate; concentrate the filtrate, concentrate The temperature is 60°C, concentrated to a specific gravity of 1.1g / ml; the concentrated solution is spray-dried at a spray-drying temperature of 150-200°C to obtain fine powder A. The fine powder A is mixed with 2g of grape seed extract to obtain a traditional Chinese medicine composition.

Embodiment 2

[0073] The preparation of embodiment 2 Chinese medicine composition

[0074] Wash 80g of Angelica sinensis, 40g of Eclipta chinensis, 40g of Ligustrum lucidum, and 50g of roses, add 2100g of drinking water, heat to 90°C, decoct in water for 3 times, and decoct for 90 minutes each time to obtain the filtrate; concentrate the filtrate, The concentration temperature is 60°C, concentrated to a specific gravity of 1.1g / ml; the concentrated solution is spray-dried at a spray-drying temperature of 150-200°C to obtain fine powder A. Mix the fine powder A with 4g of grape seed extract to obtain a traditional Chinese medicine composition.

Embodiment 3

[0075] The preparation of embodiment 3 Chinese medicine composition

[0076] Wash 40g of Angelica sinensis, 20g of Eclipta chinensis, 20g of Ligustrum lucidum, and 30g of roses, add 1100g of drinking water, heat to 120°C, and decoct in water for 3 times, each decocting for 60 minutes, to obtain the filtrate; concentrate the filtrate, The concentration temperature is 60°C, concentrated to a specific gravity of 1.1g / ml; the concentrated solution is spray-dried at a spray-drying temperature of 150-200°C to obtain fine powder A. The fine powder A is mixed with 2g of grape seed extract to obtain a traditional Chinese medicine composition.

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Abstract

The invention relates to the field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition and its application and preparation method. The traditional Chinese medicine composition is prepared from the following raw materials: extracts of angelica, eclipta, privet lucidum, rose and grape seed. In the present invention, by comparing the results of different dismantling groups, it is found that the extracts of Angelica sinensis, Eclipta chinensis, Ligustrum lucidum, roses, and grape seeds are effective in inhibiting mouse B‑16 melanoma cell activity, tyrosinase activity, and melanin production The effect of was weakened in turn, and the addition of Angelica, Eclipta, and Ligustrum lucidum had a significant impact on the results. It shows that the Chinese medicine composition provided by the invention has a reasonable formula, wherein each component is indispensable.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition and its application and preparation method. Background technique [0002] Chloasma, commonly known as "butterfly spots", "liver spots" or "pregnancy spots", is an acquired pigmentation skin disease, manifested as symmetrical pigmentation, mainly occurs on the face, especially on the cheeks, cheeks, nose, and forehead. Mainly the chin and chin, the light ones are light yellow or light brown; the severe ones are dark brown or light black. Occurring mostly in young and middle-aged women, it is one of the clinically common and difficult-to-cure skin diseases. Epidemiology shows that chloasma occurs mostly in women, and it gets worse with age. And most patients are accompanied by different degrees of menstrual disorders, insomnia, upset and irritability and other endocrine and autonomic dysfunction, which bring many troubles and ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/87A23L33/105A61P17/00
Inventor 萧伟刘崇万徐振秋柏伟荣毕宇安王跃生邓辰辰刘世娟董兴叶
Owner JIANGSU KANION PHARMA CO LTD