Alcohol-relieving medicine composition and preparation method thereof

A composition and anti-alcoholic technology, which is applied in the direction of drug combination, anti-drug, pharmaceutical formula, etc., can solve the problems of lack of products, accelerated ethanol metabolism, and single effect, so as to protect the liver, promote alcohol metabolism and excretion, and prevent drunkenness Effect

Active Publication Date: 2015-07-01
陕西中药研究所
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The current commercially available anti-alcoholic agents have the following deficiencies: the effect is relatively single, mostly acting on the liver metabolic enzyme system, accelerating the metabolism of ethanol to redu

Method used

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  • Alcohol-relieving medicine composition and preparation method thereof
  • Alcohol-relieving medicine composition and preparation method thereof
  • Alcohol-relieving medicine composition and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0047] Specific Example 1 Preparation of extract dry powder

[0048] Pueraria lobata, Hovenia dulcis, Hawthorn, Poria bark, Reed root, Tangerine peel, Schisandra, Safflower, remove the sundries from the raw materials for use. Take 4~8g Pueraria lobata, 4~8g Hovenia dulcis, 3~5g Hawthorn, 1~2.5g Poria peel, 1~5g Reed root, 2~4g tangerine peel, 3~5g Schisandra and 0.1~0.25g safflower for frying cook. For the first decoction, the medicinal materials are soaked for 0.5 to 1.5 hours, the amount of water added is 8 to 12 times, and the extraction time is 1.0 to 2.0 hours. For the second decocting, add 6 to 10 times the amount of water, and the extraction time is 0.5 to 1.5 hours. Collect and combine the extracts of the second decoction, and the specific gravity of the extracts is 1-2. Perform spray drying. Drying inlet air temperature is 180℃~210℃, outlet temperature is 80℃~110℃, atomizer rotation speed is 10000~15000r / min, peristaltic pump rotation speed is 5~20ml / min. Collect th...

Example Embodiment

[0049] Specific Example 2 Preparation of granules

[0050] The dry powder obtained by spray drying the extract of Example 1 was granulated with an appropriate amount of absolute ethanol, passed through a 10-20 mesh sieve, and dried in a constant temperature drying oven at 40-60°C for 3 to 4 hours, and then dried with 10-20 mesh The granules are obtained by sieving and sizing, and the total flavonoids in the granules are not less than 1.5%.

Example Embodiment

[0051] Specific Example 3 Preparation of buccal tablets

[0052] The dry powder obtained by spray-drying the extract of Example 1 was added with magnesium stearate at 2% of the mass of the dry powder, mixed evenly, and pressed into tablets at a pressure of 5-12KN to prepare a lozenge, the tablet weight was 0.5g, the lozenge The total flavonoids contained are not less than 0.5%.

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Abstract

The invention discloses an lcohol-relieving medicine composition and a preparation method thereof. The composition is prepared from the following components in parts by weight: 3-12 parts of flos puerariae, 3-12 parts of hovenia dulcis thunb, 3-12 parts of hawthorn, 1-9 parts of poria bark, 2-9 parts of schisandra chinensis, 2-9 parts of rhizoma phragmitis, 2-12 parts of pericarpium citri reticulatae and 0.1-3 parts of safflower carthamus. The preparation method comprises the following steps: 1, removing impurities in the raw materials; 2, decocting for the first time to obtain primary extract; 3, decocting for the second time to obtain secondary extract; 4, mixing the primary extract and the secondary extract, and performing spray drying to obtain extract dried powder; and 5, molding, and manufacturing granules, tablets or effervescent tablets. According to the mechanism and approach of alcohol absorption, metabolism and excretion, natural medicinal and edible traditional Chinese medicinal materials are adopted as raw materials and are subjected to modern extraction technology and preparation technology to prepare granules, buccal tablets and effervescent tablets having excellent comprehensive alcohol relieving effect, safety and no toxic or side effect after being taken for a long time.

Description

technical field [0001] The invention belongs to the technical field of health care and relates to a hangover composition, in particular to a hangover composition and a preparation method thereof. Background technique [0002] According to reports, there are more than 500 million drinkers in China, who cannot avoid drinking in social communication, work entertainment, etc. Among them, 60% of the drinkers drink unhealthily and drink too much; 50% of the drinkers are in sub-health and poor health. below its level. Therefore, drunkenness often occurs, and the problem of hangover also arises from it. [0003] Excessive drinking can damage the gastrointestinal tract, liver, nerves, cardiovascular and cerebrovascular organs, and can lead to mental disorders, gastric ulcers, fatty liver, alcoholic hepatitis, and cirrhosis of the liver. [0004] China is the country with the highest incidence of liver cancer in the world. According to statistics, the incidence of liver cancer in my...

Claims

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Application Information

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IPC IPC(8): A61K36/899A61P39/00
Inventor 朱爱华张亚利杨钧李存张艺芳任雷何爱武
Owner 陕西中药研究所
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