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Medicinal composition for treating piglet diarrhea and preparation method thereof

A technology of piglet diarrhea and composition, which is applied in the field of pharmaceutical composition for treating piglet diarrhea, and can solve problems such as dehydration, inconvenient treatment, untimely control of diarrhea symptoms, etc.

Active Publication Date: 2015-07-01
CHENGDU QIANKUN VETERINARY PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Its difficulty, on the one hand, is that the pathogen is complex and there are no effective preventive measures; on the other hand, it is difficult to treat the disease after it occurs.
At present, the prevention and control of piglet diarrhea usually adopts symptomatic treatment, which not only prevents secondary infection and replenishes electrolytes and water through injection of antibacterial drugs; The characteristics of rapidity, the sick piglets are often dehydrated due to untimely control of diarrhea, severe diarrhea, and eventually collapsed and died
The reason for this phenomenon, on the one hand, is that the symptoms of diarrhea are not controlled in time or the intensity of diarrhea is not controlled enough; Not unrelated
For diseases that occur in the gastrointestinal tract, it is more direct and effective to treat by oral administration; however, newborn piglets will not eat solid feed, or even swallow solid feed with too large particles; existing common solutions, pastes Although medicines, powders, and powders can be given by force-feeding, this method of administration is not only difficult, but also requires a lot of work, and it also causes a lot of stress to the newborn piglets.

Method used

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  • Medicinal composition for treating piglet diarrhea and preparation method thereof
  • Medicinal composition for treating piglet diarrhea and preparation method thereof
  • Medicinal composition for treating piglet diarrhea and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Embodiment 1 Preparation of peptide tanned orally disintegrating superfine powder tablet of the present invention

[0028] Get licorice 6kg, pulverize, pass through a 325 mesh sieve, and be licorice superfine powder; get bacitracin zinc 3kg, tannic acid protein 23kg, mix, pulverize, pass 325 mesh sieve, be peptide tanning superfine powder; Get potassium chloride 0.1kg, grain Dissolve 0.05kg of sodium phosphate (MSG) in 4kg of water; add 6kg of sucrose, heat to make a paste, add peptide tanning superfine powder, mix well, add licorice superfine powder 2kg, mix well, and make soft material; make 60 mesh Fine granules; add 0.3kg of magnesium stearate, mix well, and spheronize on a spheronizer to prepare round granules; dry; add mannitol 60kg, licorice superfine powder 4kg, low-substituted hydroxypropyl cellulose (L-HPC) 1.5kg , 0.01kg of sodium 12 alkyl sulfonate (SDS), 0.02kg of sodium glycyrrhizinate and 0.01kg of fresh milk essence, mix well, and press into 100,000 tabl...

Embodiment 2

[0029] Embodiment 2 Preparation of peptide tanned orally disintegrating superfine powder tablet of the present invention

[0030] Take 15kg of licorice, crush it, pass through a 325 mesh sieve, and get licorice superfine powder; take 6kg of bacitracin zinc, 12kg of protein tannin, mix, crush, pass through a 325 mesh sieve, and get peptide tanning superfine powder; take 1kg of potassium chloride, MSG 0.3 kg is dissolved in 2kg of water; add 20kg of sucrose, heat to make a paste, add peptide tanning superfine powder, mix well, add licorice superfine powder 5kg, mix well, and make soft material; make 60 mesh fine particles; add stearic acid Magnesium 1.1kg, mixed evenly, prepared into round granules by spheronizing on a spheronizer; drying; adding mannitol 41kg, licorice superfine powder 10kg, L-HPC 3kg, SDS 0.2kg, sodium glycyrrhizinate 0.2kg and fresh milk essence 0.2kg, Mix well and press into 100,000 tablets.

Embodiment 3

[0031] Embodiment 3 Preparation of Peptide Tanning Orally Disintegrating Superfine Powder Tablets of the Present Invention

[0032] Take 26kg of licorice, crush it, pass through a 325 mesh sieve, and get licorice superfine powder; take 9kg of bacitracin zinc, 6kg of protein tannin, mix, crush, pass through a 325 mesh sieve, and get peptide tanning superfine powder; take 3kg of potassium chloride, MSG 0.7 kg dissolved in 5kg of water; add 30kg of sucrose, heat to make a paste, add peptide tanned superfine powder, mix well, add licorice superfine powder 15kg, mix well, make soft material; make 60 mesh fine particles; add stearic acid Magnesium 2.3kg, mixed evenly, spheronized on the upper spheronizer to prepare round particles; dried; added mannitol 16kg, licorice superfine powder 11kg, L-HPC 5kg, SDS 1kg, sodium glycyrrhizinate 0.5kg and fresh milk flavor 0.5kg, mixed Evenly, pressed into 100,000 pieces.

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PUM

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Abstract

The invention provides a medicinal composition for treating piglet diarrhea. The medicinal composition is prepared from the following raw materials in parts by weight: 1-11 parts of bacitracin zinc, and 4-26 parts of tannalbin. The invention further provides a preparation method and application of the medicinal composition. The invention provides a taste-modifying super-micronized fast disintegrating oral tablet. The tablet integrates the function of resisting infection, relieving diarrhea, detoxifying, supplementing electrolyte and promoting growth, and can be disintegrated by means of a little saliva in the oral cavity of a piglet to form paste, and the paste can be easily swallowed to the gastrointestinal tract, so that the purpose of effectively preventing and treating piglet diarrhea is fulfilled.

Description

technical field [0001] The invention relates to a pharmaceutical composition for treating piglet diarrhea. Background technique [0002] Piglet diarrhea has been a technical problem that has plagued pig farming for a long time. Especially in recent years, both the incidence and the mortality rate of piglet diarrhea have been increasing year by year. Its difficulty, on the one hand, is that the pathogen is complex and there are no effective preventive measures; on the other hand, it is difficult to treat the disease after it occurs. At present, the prevention and control of piglet diarrhea usually adopts symptomatic treatment, which not only prevents secondary infection and replenishes electrolytes and water through injection of antibacterial drugs; Rapid characteristics, the diseased piglets are often due to untimely control of diarrhea, strong diarrhea leads to dehydration, and eventually collapse and die. The reason for this phenomenon, on the one hand, is that the sympt...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/12A61K9/20A61P1/12A61P3/12A61P31/04A61K33/14A61K31/704A61K38/00
Inventor 丁晓刚杨森房春林
Owner CHENGDU QIANKUN VETERINARY PHARMA
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