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Three-input three-output DNA algorithm self-assembly hexagon structure model

A structural model and hexagonal technology, applied in computing, instruments, electrical digital data processing, etc., can solve problems such as large mismatch rate, and achieve the effect of improving reliability and improving mismatch rate

Inactive Publication Date: 2015-07-01
HUAZHONG UNIV OF SCI & TECH
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Problems solved by technology

[0004] The present invention proposes a three-input and three-output DNA algorithm self-assembly hexagonal structure model, which can effectively improve the problem of large mismatch rate of traditional algorithm self-assembly and improve the reliability of self-assembly

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Embodiment Construction

[0016] In order to better understand the present invention, the embodiments of the invention will be described in detail below in conjunction with the accompanying drawings.

[0017] Please refer to figure 1 , a schematic diagram of the DNA algorithm self-assembling hexagon in a preferred embodiment of the present invention. Since the hexagonal structure is simple and stable and has three directions, it can realize the function of three inputs and three outputs at most, for example, it can be used to build a full adder (three inputs and two outputs).

[0018] Please refer to figure 2 , based on the DNA algorithm self-assembled hexagonal model, two 0-strands and two 1-strands were designed, and the end of the 1-strand was connected with gold nanoparticles as a marker, and the DNA single-strand hexagonal model used different coding sequences to distinguish the input and output ends. Logical 0 or 1, so that they can not only expand in the plane, but also the adjacent hexagons ...

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Abstract

The invention provides a three-input three-output DNA algorithm self-assembly hexagon structure model. A three-input three-output hexagon structure subelement is composed of a DNA single chain, different coding sequences are used in six edges of the hexagon single chain, and a three-input three-output algorithm can be executed in three directions. Exclusive OR logic is executed through base complementary pairing based on the DNA hexagon model to form an exclusive-OR gate compound Sierpinski triangle for proving the reliability of self-assembly logic of the model. The model can effectively solve the problem that a tradition algorithm is high in self-assembly mispairing rate, and the self-assembly reliability is improved. Due to the fact that a hexagon structure has three input-output directions, the single hexagon structure model can achieve three-input three-output logic functions at most, and a plurality of cascaded hexagon structures can achieve more complex multi-input multi-output operation, which is a breakthrough in the field of DNA calculation.

Description

technical field [0001] The invention relates to the fields of DNA self-assembly and DNA calculation, in particular to a three-input and three-output DNA algorithm self-assembly hexagonal structure model. Background technique [0002] DNA, with its unique double helix structure and complementary base pairing characteristics, is very suitable for programmed self-assembly process. The research on DNA-based bottom-up self-assembly began 30 years ago and has attracted many laboratories around the world to carry out related research. The DNA algorithm self-assembly is based on the DNA tile structure, which is a cluster of DNA crossover molecules with a branched structure. Each molecule has a sticky end, which can be combined with other complementary DNA tiles to gradually form a DNA molecular network structure. This DNA algorithm self-assembly network structure has strong programmability, no human intervention is required in the formation process, and the calculation parallelism ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G06F19/12
Inventor 石晓龙陈智华张征潘林强刘倩宋弢王之煜武晓旭陈从周沈涛
Owner HUAZHONG UNIV OF SCI & TECH
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