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Pharmaceutical composition for treating infantile hernia and preparation method of pharmaceutical composition

A technology of children's hernia and composition, which is applied in the direction of drug combination, pharmaceutical formula, medical preparations containing active ingredients, etc., can solve problems such as many side effects, irritability, easy recurrence, etc., achieve short treatment period, promote healing, curative effect

Inactive Publication Date: 2015-07-22
郭延举
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

3. Once the hernia mass is incarcerated (the hernia mass cannot be retracted), there will be abdominal pain, nausea, vomiting, fever, anorexia or crying, irritability
3. Sometimes there is intestinal obstruction; the probability of suffering from hernia and incarceration in children is high
2. Although more boys suffer from hernias, girls also suffer from hernias
[0009] At present, because western medicine cannot effectively treat hernia in children, and it is easy to relapse, and has many side effects, therefore, there is a great demand for drugs that can effectively treat hernia in children

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0074] When the dosage form of described medicine is honey refining pill, its preparation method may further comprise the steps:

[0075] The first step is to distill and crystallize pinellia, magnolia bark, sword bean, white mustard seed, Cyperus cyperi, curcuma, mimosa, and Geshanxiang into powder;

[0076] The second step is to mix the remaining raw materials in proportion, add 3-5 times the amount of 70-95% ethanol to the mixture, soak for 0.5-1.5 hours, heat and extract 1-2 times, each time for 0.5-1.0 hours, and filter to obtain The extract and dregs are ready for use, the extract is combined, and then ultrafiltered through an ultrafiltration column with a cut-off molecular weight of 38,000-84,000, the ultrafiltration removes ethanol under reduced pressure, and is concentrated into an extract with a relative density of 1.03 at 85-92°C to form a composition points 1;

[0077] The third step is to soak the medicinal dregs obtained above with 2-3 times the amount of water ...

Embodiment 1

[0088] Embodiment 1 honey refining pill

[0089] The preparation process of the honey refining pill of the present invention is: get 240g of Huoxuelian, 150g of Akebia, 320g of Achyranthes bidentata, 200g of Daxueteng, 170g of triangular, 350g of iron-coated gold, 230g of Chuanxiong, 200g of Baichangxiong, 280g of pumice, 20g of dried peach , Huang Yaozi 220g, Natural Copper 340g, Stone Flower 210g, Pinellia 20g, Magnolia officinalis 380g, Sword Bean 400g, White Mustard Seed 330g, Cyperus Cyperi 210g, Curcuma 180g, Mimosa 30g, Geshanxiang 220g, Fengfengsan 300g, Wuyepao 200g , Gansong 330g, ivy 250g, radish 310g and betel nut 240g;

[0090] The first step is to distill and crystallize pinellia, magnolia bark, sword bean, white mustard seed, Cyperus cyperi, curcuma, mimosa, and Geshanxiang into powder;

[0091] The second step is to mix the remaining raw medicinal materials in proportion, add 85% ethanol which is 4 times the amount of the mixture, soak for 1 hour, heat and ext...

Embodiment 2

[0094] Example 2 Capsules

[0095] The manufacture process of capsule of the present invention is: get Huoxuelian 330g, Akebia 200g, Achyranthes bidentata 240g, Daxueteng 350g, triangular 240g, iron-coated gold 250g, Rhizoma Chuanxiong 300g, Baichang 170g, pumice 320g, dried peach 20g, Huang Yaozi 140g, Natural Copper 260g, Stone Flower 180g, Pinellia 30g, Magnolia officinalis 260g, Sword Bean 350g, White Mustard Seed 250g, Cyperus Cyperi 180g, Curcuma 300g, Mimosa 30g, Geshanxiang 120g, Fengfengsan 360g, Wuyepao 250g, Nardin 110g, ivy 200g, radish 310g and betel nut 160g;

[0096] The first step is to mix the raw materials of the traditional Chinese medicine in proportion, add ethanol with an alcohol concentration of 90% which is three times the mass of the mixture, heat and reflux for an hour, extract, and filter to obtain the first extract; Add ethanol with an alcohol concentration of 85% that is twice the mass of the medicinal residues, heat and reflux for 2 hours, extrac...

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Abstract

The invention discloses a pharmaceutical composition for treating infantile hernia and a preparation method of the pharmaceutical composition. The pharmaceutical composition is prepared from the following raw herbal materials: sheathed monkshood root, akebiaquinata, achyranthes aspera, sargentgloryvine stem, rhizoma sparganii, berchemia lineate, ligusticum wallichii, calamus, pumice, fructus persicae immaturus, air potato, natural copper, parmelia tinctourium, pinellia ternate, mangnolia officinalis, sword bean, semen brassicae, rhizoma cyperi, curcuma zedoary, sensitive plant, angelica citriodora hance, oblongleaf kadsura stem root, root or leaf of cochinchina raspberry, rhizoma nardostachyos, ivy, semen raphani, betel nut, procumbent speedwell, campsis grandiflora, brucea javanica, dutchmanspipe root and indian kalimeris herb. The pharmaceutical composition has the beneficial effects of promoting blood circulation to remove blood stasis, eliminating goiter and removing stasis, promoting qi circulation to relieve pain, opening depression, and guiding qi downward, is mainly used for promoting infantile hernia to heal, and has the advantages of quick effect-taking, high effective rate, exact curative effect, short course of treatment, no toxic or side effect, low price, and the like.

Description

technical field [0001] The invention relates to the technical field of pharmaceutical preparations, in particular to a pharmaceutical composition for treating hernia in children and a preparation method thereof. Background technique [0002] Infantile inguinal hernia, commonly known as inguinal hernia, is the most common disease in pediatric general surgery. During the embryonic period, there is a "peritoneal sheath" in the groin, which can help the testis to descend into the scrotum or fix the round ligament of the uterus. After the child is born, the sheath-like process does not close completely, causing the small intestine, omentum, ovary, and fallopian tubes in the abdominal cavity to enter the sheath-like process, which becomes a hernia. If only peritoneal fluid enters the scrotum, it is scrotal edema. The general incidence of hernia is 1-4%, boys are 10 times that of girls, and it is higher in premature babies, and it may occur on both sides. [0003] Inguinal herni...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61P43/00A61K33/26
Inventor 秦永春朱甲峰匡立山郭延举肖龙明程绪鹏
Owner 郭延举
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