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A kind of starch film-forming composition

A technology of composition and starch film, which is applied in the directions of non-active ingredient medical preparations, capsule delivery, pharmaceutical formulations, etc., can solve the problems of high cost and low profit margin of hydroxypropyl starch

Active Publication Date: 2017-04-26
HUNAN ER KANG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the cost of hydroxypropyl starch is relatively high, and the profit margin generated by industrialized mass production is relatively low

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Soluble starch made from cornstarch 40kg

[0022] Pregelatinized starch with a degree of pregelatinization of 40 4kg

[0023] Prepare glue with starch and water, and make the viscosity of the glue be 250-400 mPas at 30°C. When the temperature of the glue is at 70°C and the automatic film coating machine is preheated to 20°C, stick the glue, and finally use The thickness of the starch film is controlled at 0.3 mm, and then dried to obtain the starch film. The tensile strength of the film was determined to be 15MPa.

Embodiment 2

[0025] Soluble starch made from potato starch 50kg

[0026] Pregelatinized starch with a degree of pregelatinization of 53 10kg

[0027] Prepare glue with starch and water, and make the viscosity of the glue be 250-400 mPas at 30°C. When the temperature of the glue is 75°C and the viscose mold is preheated to 25°C, glue the glue and finally make the starch film The thickness of the starch is controlled at 0.2mm, and then dried to obtain a starch film. Measured by the same method as in Example 1, the tensile strength of the film is 30MPa.

Embodiment 3

[0029] Soluble starch made from sweet potato starch 45kg

[0030] Pregelatinized starch with a pregelatinization degree of 60 5kg

[0031] Prepare glue with starch and water, and make the viscosity of the glue be 250-400 mPas at 30°C. When the temperature of the glue is 75°C and the viscose mold is preheated to 25°C, glue the glue and finally make the starch film The thickness of the starch is controlled at 0.2mm, and then dried to obtain a starch film. Measured by the same method as in Example 1, the tensile strength of the film is 18MPa.

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Abstract

The invention discloses a starch film-forming composition. Through a large number of repeated studies, a starch film-forming composition was found out, and its raw materials were composed of soluble starch and pregelatinized starch. The starch composition has excellent mechanical properties and film-forming properties, and the prepared film-forming substance has good transparent surface gloss.

Description

technical field [0001] The invention relates to a starch film-forming composition, which can also be used to prepare capsules, and belongs to the field of starch or starch derivative processing and also belongs to the field of pharmaceutical processing. Background technique [0002] Starches and modified starches are often used in the food or pharmaceutical processing industries. Through the physical and chemical modification of native starch, it has the characteristics that native starch does not have, such as improving fluidity, water solubility, film-forming property, mechanical strength, etc. Both soluble starch and pregelatinized starch are modified starch. [0003] Soluble starch is white or off-white powder, non-toxic and harmless, good solubility in hot water, stable chemical properties, low reducibility, strong adsorption, good fluidity, and no moisture absorption. Soluble starch can be used as thickener, stabilizer, filler, sugar-free drug excipient, etc. Pregel...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C08L3/04A61K9/48A61K47/36
Inventor 帅放文王向峰章家伟
Owner HUNAN ER KANG PHARMA