Use of FAM135B inhibitor in treatment and/or prevention of esophageal squamous cancer

A FAM135B and inhibitor technology, applied in gene therapy, DNA/RNA fragments, recombinant DNA technology, etc., can solve problems such as no related reports
CN104873973AActive Publication Date: 2015-09-02CANCER INST & HOSPITAL CHINESE ACADEMY OF MEDICAL SCI
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
CANCER INST & HOSPITAL CHINESE ACADEMY OF MEDICAL SCI
Publication Date
2015-09-02

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Abstract

The invention relates to the use of an FAM135B inhibitor in treatment and / or prevention of the esophageal squamous cancer. Further the invention relates to the use of the FAM135B genome mutation in diagnosis and / or prognosis of the esophageal squamous cancer.
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Description

technical field

[0001] The present invention relates to the technical field of FAM135B inhibitor in the treatment and / or prevention of esophageal squamous cell carcinoma. On the other hand, the present invention relates to the technical field of FAM135B gene mutation in the diagnosis and / or prognosis of esophageal squamous cell carcinoma. Background technique

[0002] Esophageal cancer is a common digestive tract tumor. About 300,000 people die from esophageal cancer every year in the world, and it is the sixth leading cause of cancer death in the world. See Kamangar, F., G.M.Dores, et al. (2006). "Patterns of cancer incidence, mortality, and prevalence across five continents: defining priorities to reduce cancer disparities in different geographic regions of the world." J Clin Oncol 24(14):2137-2150. About 70% of esophageal cancer in the world occurs in China, and 90% of esophageal cancer in China is esophageal squamous cell carcinoma. So far, little is known about the me...

Claims

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