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A liquid nitrogen level control and display device for hyperpolarized xenon collection

A display device, liquid level control technology, applied in applications, medical science, sensors, etc., to achieve the effect of speeding up depolarization and preventing waste

Active Publication Date: 2017-12-19
WUHAN INST OF PHYSICS & MATHEMATICS CHINESE ACADEMY OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The invention aims at the problem of controlling and displaying the position of the liquid nitrogen liquid level without introducing an external magnetic field in the process of collecting hyperpolarized xenon, and proposes a liquid nitrogen level control for collecting hyperpolarized xenon and display device

Method used

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  • A liquid nitrogen level control and display device for hyperpolarized xenon collection
  • A liquid nitrogen level control and display device for hyperpolarized xenon collection
  • A liquid nitrogen level control and display device for hyperpolarized xenon collection

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Embodiment 1

[0031] Such as Figure 1-3 As shown, the hyperpolarized xenon-nitrogen mixed gas will pass into the cold trap 7 from the first air inlet or the second air inlet of the cold trap. If the position of liquid nitrogen liquid level is controlled reasonably, because the solidification temperature of xenon is higher than liquid nitrogen temperature, so xenon gas can become solid, stays in cold trap 7 bottoms. Nitrogen remains in gaseous state and is discharged from the first gas outlet or the second gas outlet, thereby realizing the purification and collection of hyperpolarized xenon. figure 1 1 in is the liquid nitrogen injector, and the filling speed can be controlled through the filling valve on the injector. figure 1 2 in the liquid nitrogen tank, when adjusting the filling speed of the liquid nitrogen injector to be greater than the volatilization speed of liquid nitrogen in the liquid nitrogen tank 2, the liquid nitrogen liquid level in the liquid nitrogen tank 2 will rise to ...

Embodiment 2

[0034] Under the following experimental conditions: the diameter of the cold trap 7 is 3 cm, the diameter of the liquid nitrogen tank 2 is 6 cm, the magnet 8 provides a static magnetic field of 2000G, the flow rate of the liquid nitrogen injector 1 is 0.05 L / min, and the liquid nitrogen level is controlled at the inlet pipe of the cold trap. Within the height of 2mm above and below the bottom, the ratio of xenon-nitrogen mixed gas is xenon 2% nitrogen 98%, and the ventilation time is 30 minutes. The purity of the purified xenon is 99%, and the retention rate of xenon is 99.2%.

[0035] Under other conditions being the same, when the liquid nitrogen liquid level control is not carried out, when the initial liquid nitrogen liquid level is filled to 3cm above the bottom of the cold trap inlet pipe, when the device works for 15 minutes, the inlet pipe is blocked and cannot continue normal work. The purity of the purified xenon is 82%, and the retention rate of xenon is 99.3%.

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Abstract

The invention discloses a liquid nitrogen level control and display device for collecting hyperpolarized xenon. The liquid nitrogen level control and display device mainly comprises a liquid nitrogen injector, a liquid nitrogen tank, a liquid level indicator marker rod, a Dewar flask, a liquid nitrogen recovery connector and the like. The liquid nitrogen level control and display device has the advantages that the liquid nitrogen level is automatically controlled and displayed in the process of collecting the hyperpolarized xenon, and hyperpolarized xenon waste, hyperpolarized xenon purity decline and air circuit blockage caused by instability of the liquid nitrogen level during the process of collecting the hyperpolarized xenon can be effectively avoided.

Description

technical field [0001] The invention relates to the technical field of lung magnetic resonance imaging (Magnetic Resonance Imaging, MRI), in particular to a liquid nitrogen level control and display device for collecting hyperpolarized xenon. Background technique [0002] Magnetic Resonance Imaging (MRI) technology is non-invasive and non-radioactive, and can be used to obtain images of most tissues and organs of the human body. It has been widely used in in vivo imaging and clinical disease diagnosis. But traditionally based on protons ( 1 H) The MRI technique is not suitable for the lungs. The lungs can be imaged using hyperpolarized xenon as a contrast agent. [0003] The signal-to-noise ratio of the signal obtained during imaging is proportional to the degree of polarization of the hyperpolarized xenon. In the prior art, the production rate in the process of preparing hyperpolarized xenon is low, and it is difficult to meet the needs of production and use. At the sam...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61B5/055
CPCA61B5/055
Inventor 周欣阮伟伟吕植成孙献平刘买利叶朝辉
Owner WUHAN INST OF PHYSICS & MATHEMATICS CHINESE ACADEMY OF SCI