Portable breath volatile organic compounds analyzer and corresponding unit

A technology of organic compounds and analyzers, applied in the field of detection and quantification of VOC in exhaled breath, which can solve the problems of not realizing the exhaled VOC analyzer

Inactive Publication Date: 2015-10-21
OXFORD MEDICAL DIAGNOSTICS LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Thus, despite a recognized need for a compact breath VOC analyzer, none of the currently proposed technologies have achieved one.

Method used

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  • Portable breath volatile organic compounds analyzer and corresponding unit
  • Portable breath volatile organic compounds analyzer and corresponding unit
  • Portable breath volatile organic compounds analyzer and corresponding unit

Examples

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Embodiment Construction

[0036] Such as figure 1 As shown, a handheld breath VOC analyzer 100 according to one embodiment of the present invention includes a sample inlet 10 to which a mouthpiece or mask can be attached to allow a subject to exhale into the device. The analyzer 100 includes a gas handling system for transporting samples as well as ambient air through the analyzer, the gas handling system comprising several valves 12 , gas lines 13 , pump 6 and flow sensor 3 . The various major components of the analyzer 100 and the valve 12 are controlled by the control system 200 .

[0037] In the illustrated embodiment, the gas treatment system includes a differential pressure sensor as flow sensor 3 to measure the volume of exhaled breath. This amount is later used for standardization purposes and for selecting the fraction of exhaled breath to be delivered to the preconcentrator 2 . The preconcentrator 2 contains a hydrophobic adsorbent material such as Porapak Q (eg 0.6 grams) held in a metal (...

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Abstract

A compact, portable or handheld device for measurement of breath VOCs such as acetone is described, which incorporates a flow measurement sensor, a mini preconcentrator unit and an spectroscopy unit, such as a cavity-enhanced absorption spectrometer. The preconcentrator includes a chemically selective material to trap VOCs, which is supported on a metal foam. The apparatus is suitable for measuring sub ppm levels of breath VOCs such as acetone and for tracking blood ketone levels.

Description

technical field [0001] The present invention relates to a portable (more preferably hand-held) analyzer device for detecting and quantifying volatile organic compounds (VOCs) in breath, and to a method of detecting and quantifying VOCs in breath using such a device . Specifically, it is able to detect and quantify ketones such as acetone in breath. Background technique [0002] It has long been believed that the level of acetone in exhaled breath, a marker of blood ketones, could be used as a possible marker of changes in blood glucose levels in type 1 diabetes. Exhaled acetone levels are also sensitive to diet and exercise, and thus monitoring them can be helpful in assessing the status of diet and exercise. [0003] Type 1 diabetics must continuously measure their blood sugar levels by checking several times a day. It is also recommended that diabetics who are feeling unwell or at the onset of diabetes also measure their blood ketones to prevent diabetic ketoacidosis (D...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/497G01N1/40A61B5/08
CPCA61B5/082A61B5/0075A61B5/14532G01N1/22G01N33/497G01N2001/2244G01N2001/2276
Inventor 罗伯特·派维罗尔格雷厄姆·汉考克格朗特·安德鲁·戴德曼·里奇
Owner OXFORD MEDICAL DIAGNOSTICS LTD
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