Medicine composition for promoting wound healing.
A wound healing and composition technology, applied in the field of medicine, can solve the problems of slow healing, unfavorable clinical use, etc.
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Embodiment 1
[0035] Example 1 Preparation of egg yolk oil
[0036] (1) After breaking the eggs, use an egg white separator to separate the egg yolks, ripen at 100-105 °C, pulverize, continue drying at 70-80 °C until moisture ≤ 5%, pulverize, and pass through a No. 1 sieve to obtain egg yolk powder.
[0037] (2) Take 1000 g of egg yolk powder, measure its water content ≤ 5%, extract egg yolk oil by supercritical carbon dioxide extraction, the extraction temperature is 50 ° C, the extraction pressure is 35 Mpa, CO 2 The flow rate was 50L / h, and the extraction time was 120min to obtain egg yolk oil.
Embodiment 2
[0038] Example 2 Preparation of egg yolk lecithin
[0039] (1) After breaking the eggs, use an egg white separator to separate the egg yolks, ripen at 100-105 °C, pulverize, continue drying at 70-80 °C until moisture ≤ 5%, pulverize, and pass through a No. 1 sieve to obtain egg yolk powder.
[0040] (2) Take 1000 g of egg yolk powder, measure its water content ≤ 5%, extract egg yolk oil by supercritical carbon dioxide extraction, the extraction temperature is 50 ° C, the extraction pressure is 35 Mpa, CO 2 The flow rate was 50L / h, the extraction time was 120min, the egg yolk oil was removed, and the remaining egg yolk residue was collected.
[0041] (3) Take 500g of the above-mentioned egg yolk residue, add 4 times the amount of 90% ethanol (that is, 2000ml ethanol), and extract at a fixed extraction temperature of 30°C for 4 times, each time for 1.5h (continuous stirring during the extraction process, the rotation speed is 150 rpm), The filtrates were combined, and ethanol w...
Embodiment 3
[0042] Example 3 Preparation of formulations for transdermal administration
[0043] Get 700g of egg yolk oil prepared in Example 1, 300g of egg yolk lecithin prepared in Example 2, mix, add 100g of glycerin, 0.1g of rosemary essential oil, 2.5g of carbomer to make a commonly used transdermal drug delivery preparation .
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