Medicine for treating infant damp-heat type diarrhea and preparation method thereof

A damp-heat technology for infants and young children, applied in the field of pharmaceutical preparations, can solve the problems of heavy gastrointestinal burden, drug influence, toxic and side effects, and achieve the effects of protecting gastrointestinal mucosa, enhancing resistance, and having no toxic and side effects.

Inactive Publication Date: 2015-11-25
JINAN SHUNHAO BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Causes of diarrhea in infants and young children: 1. Physical factors: This disease mainly occurs in infants and young children. heavy burden
(2) Nervous, endocrine, circulatory system, liver and kidney functions are immature in infancy, and the regulation function is poor
(3) The baby's immune function is not perfect
(4) The body fluid distribution of infants is different from that of adults. The propor

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0073] When the dosage form of described medicine is capsule, its preparation method comprises the following steps:

[0074] The first step is to mix the various raw materials of the drug in proportion, add ethanol with an alcohol concentration of 85-95% relative to the mass of the mixture, heat and reflux for 1-3 hours, extract, and filter to obtain the first extract ; The medicinal residue obtained by filtering is then added with ethanol with an alcohol concentration of 85-95% relative to the quality of the medicinal residue 1-2 times, heated and refluxed for 1-3 hours, extracted, and filtered to obtain the second extract; the first extracted The liquid and the second extract are combined, concentrated under reduced pressure to remove the ethanol solvent, and dried to obtain a dry paste;

[0075] In the second step, the dry paste obtained in the first step is placed in an ultrafine pulverizer for 1 to 2 hours, pulverized, and sieved to obtain an ultrafine powder of 300 mesh ...

Embodiment 1

[0087] Embodiment 1 capsule

[0088] The production process of the capsule of the present invention is as follows: take 150g of Peilan, 320g of red cohosh, 220g of salvia miltiorrhiza, 160g of Datouchen, 250g of Shenjincao, 180g of Shijianchuan, 330g of Vitex vitex, 30g of Jiulixiang, 200g of brassica seed, 210g Grass Fragrance, 330g Scutellaria Scutellariae, 210g Salsa Seed, 300g Spoonleaf Grass, 220g Polygonum Polygonum, 180g Pseudostellaria, 270g Licorice, 160g Scallop, 320g Green Arrow, 190g Eupatoria, 340g Aurora, Rubia 220g, Atractylodes macrocephala 180g, Geli juice 170g, Shixiang 150g, Asarum 220g, Mabi wood 310g, Myrrh 270g, Angelica dahurica 160g, Astragalus 320g, Wild berry 180g, Raisin 350g, Achyranthes bidentata 150g, Basil 210g, Celandine 20g and Smilax 200g:

[0089] The first step is to mix the raw materials of the drug in proportion, add ethanol with an alcohol concentration of 90% that is three times the mass of the mixture, heat and reflux for 2 hours, extr...

Embodiment 2

[0092] Embodiment 2 Granules

[0093] The preparation process of the granule of the present invention is as follows: take 140g of Peilan, 350g of red cohosh, 210g of salvia miltiorrhiza, 180g of Datouchen, 260g of Shenjincao, 150g of Shi Jianchuan, 330g of Vitex leaves, 40g of Jiulixiang, 270g of brassica seeds, 200g of Herbs, 330g of Scutellaria barbata, 210g of Salsa, 300g of Spoonleaf, 230g of Polygonum, 300g of Radix Pseudostellariae, 280g of Licorice, 170g of Scallops, 150g of Green Arrow, 200g of Eupatorium, 350g of Rhizoma, 220g of Rubia, Atractylodes macrocephala 150g, Geli juice 180g, Shixiang 150g, Asarum 220g, Mabi wood 300g, Myrrh 350g, Angelica dahurica 240g, Astragalus 320g, Wild berry 190g, Raisin 340g, Achyranthes bidentata 160g, Basil 250g, Celandine 30g and 220g of sarsaparilla;

[0094] The first step is to mix the raw materials of the medicine according to the stated ratio, add ethanol with an alcohol concentration 6 times that of the mixture and be 85% et...

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PUM

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Abstract

The invention discloses medicine for treating infant damp-heat type diarrhea and a preparation method thereof. The medicine comprises the following raw medicinal materials: eupatorium fortunei, astilbe chinensis, radix salviae miltiorrhizae, adenosma indianum, herba lycopodii, Chinese sage herb, folium viticis negundo, folium et cacumen murrayae, seeds of brassica campestris, lysimachia sikokiana, herba scutellariae barbatae, semen aesculi, latouchea fokiensis, persicaria hydropiper, radix pseudostellariae, radix glycyrrhizae, bulbus allii macrostemonis, aster ageratoides, herba lycopi, common origanum herb, radix rubiae, rhizoma atractylodis macrocephalae, vitis flexuosa juice, mosla Chinensis maxim, herba asari, pittosporumlike nothapodytes, myrrh, radix angelicae, radix astragali, elsholtzia rugulosa, semen raphani, achyranthes aspera, sweet basil herb, greater celandine herb and chinaroot greenbier rhizome. The medicine has the benefits of having the efficacies of relieving exterior syndrome, resolving dampness, regulating qi, regulating the middle warmer, and activating blood circulation to remove blood stasis, having the effects of protecting gastrointestinal mucous membrane, enhancing resistance and relieving pain, and having the advantages of taking effect quickly, and being high in efficiency, accurate in curative effect, short in treatment course, free of toxic and side effects, low in price, and the like.

Description

technical field [0001] The invention relates to the technical field of pharmaceutical preparations, in particular to a medicine for treating damp-heat diarrhea in infants and a preparation method thereof. Background technique [0002] Infant diarrhea, also known as infant dyspepsia, is a syndrome of acute gastrointestinal dysfunction in infants and young children, mainly characterized by diarrhea and vomiting, with the highest incidence in summer and autumn. The pathogenic factors of this disease are divided into three aspects: constitution, infection and digestive disorder. The main clinical manifestations are increased stool frequency, loose stools, and water and electrolyte disturbances. If the disease is not treated in time, severe water and electrolyte imbalance may endanger the life of children. [0003] Causes of diarrhea in infants and young children: 1. Physical factors: This disease mainly occurs in infants and young children. Heavy burden. (2) Nervous, endoc...

Claims

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Application Information

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IPC IPC(8): A61K36/8962A61K36/90A61P1/12A61P1/00
Inventor 张庆彪孔令禹
Owner JINAN SHUNHAO BIOTECH CO LTD
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