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Single particle scattering measurement method based on microfluidic chip particle capturing

A microfluidic chip, scattering measurement technology, applied in the field of optics and measurement, can solve the problems of large-angle single-particle scattering field measurement, the problem of single-particle environment construction, etc., and achieve the effect of measurement

Active Publication Date: 2015-12-09
HUAZHONG UNIV OF SCI & TECH
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Problems solved by technology

[0006] Aiming at the defects of the prior art, the purpose of the present invention is to measure the scattering field distribution of a single particle in a large angle range in a plane, aiming to solve the problem of single particle environment construction in the original scheme and the defect that the single particle scattering field cannot be measured at a large angle

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  • Single particle scattering measurement method based on microfluidic chip particle capturing
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  • Single particle scattering measurement method based on microfluidic chip particle capturing

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Embodiment Construction

[0033] In order to make the objectives, technical solutions and advantages of the present invention clearer, the following further describes the present invention in detail with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the present invention, but not to limit the present invention.

[0034] The measurement method involved in the present invention includes five steps of microfluidic chip design, measurement environment configuration, alignment, single particle capture and single particle environment construction, and single particle scattering measurement, which are respectively introduced as follows.

[0035] Among them, the microfluidic chip design includes the following steps in this embodiment.

[0036] (1) A chip template is made on a single crystal silicon wafer by a photolithography process; the chip flow channel structure is an open circular flow channel, one end of th...

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Abstract

The present invention discloses a single particle scattering measurement method based on microfluidic chip particle capturing. The single particle scattering measurement method comprises microfluidic chip design production, measuring environment configuration, aligning, single particle capturing and single particle environment constructing, single particle large angle scattering distribution determining and other correlated methods. Compared with the method in the prior art, the method of the present invention has the following characteristics that: the microfluidic chip particle capturing technology is combined, such that the disadvantages of the single-particle large-angle scattering and the light scattering characteristic measurement method within the large dynamic range are overcome, and the single particle large angle scattering distribution measurement is achieved.

Description

Technical field [0001] The invention belongs to the field of optics and measurement, and more specifically, relates to a single particle scattering measurement method based on a microfluidic chip particle capture. Background technique [0002] As an important feature in photoelectric detection, light scattering has an important effect on the analysis of detection results, and is widely used in many fields of photodetection. There are a large number of related theories and experiments for the study of light scattering characteristics of particles, such as Mie scattering theory, T matrix method, and other related theoretical methods that can predict and analyze particle surface shape and scattering function distribution; the corresponding particle scattering function There are also many researches on measurement methods, such as dynamic light scattering, laser-induced visible light method, and extinction measurement method. In addition, many particle scattering measurement devices...

Claims

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Application Information

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IPC IPC(8): G01N21/49
Inventor 杨克成夏珉戴杰宫宝玉
Owner HUAZHONG UNIV OF SCI & TECH
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